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    Items: 1 to 20 of 88

    1.
    Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure
    Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer
    Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y
    PMCID:
    PMC11447256
    AbstractArticlePDF–2.8M
    2.
    Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein
    Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo
    J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390
    PMCID:
    PMC11237930
    AbstractArticlePDF–3.8M
    3.
    Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
    Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
    Cell. Author manuscript; available in PMC 2024 Oct 26.
    Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
    PMCID:
    PMC11209935
    AbstractArticlePDF–3.0M
    4.
    ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis
    Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge
    Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335
    PMCID:
    PMC10627786
    AbstractArticlePDF–5.2M
    5.
    TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
    Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
    Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
    PMCID:
    PMC10237422
    AbstractArticlePDF–23M
    6.
    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
    Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
    Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
    PMCID:
    PMC10072906
    AbstractArticlePDF–4.2M
    7.
    CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
    Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
    Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
    PMCID:
    PMC9950183
    AbstractArticlePDF–2.4M
    8.
    FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia
    Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen
    J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0
    PMCID:
    PMC9922468
    AbstractArticlePDF–4.9M
    9.
    A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
    Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
    Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
    Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
    PMCID:
    PMC9769698
    AbstractArticlePDF–2.7M
    10.
    Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
    Zhuoyao Chen, Rafael M. Ioris, Stacey Richardson, Ava N. Van Ess, Iolanda Vendrell, Benedikt M. Kessler, Francesca M. Buffa, Luca Busino, Steven C. Clifford, Alex N. Bullock, Vincenzo D’Angiolella
    Cell Death Differ. 2022 Oct; 29(10): 1955–1969. Published online 2022 Apr 4. doi: 10.1038/s41418-022-00983-4
    PMCID:
    PMC9525703
    AbstractArticlePDF–4.4M
    11.
    ALS-linked loss of Cyclin-F function affects HSP90
    Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
    Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
    PMCID:
    PMC9481933
    AbstractArticlePDF–3.5M
    12.
    HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
    Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
    Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
    PMCID:
    PMC9338313
    AbstractArticlePDF–2.8M
    13.
    ARAF protein kinase activates RAS by antagonizing its binding to the RASGAP NF1
    Wenjing Su, Radha Mukherjee, Rona Yaeger, Jieun Son, Jianing Xu, Na Na, Neilawattie Merna Timaul, Jaclyn Hechtman, Viktoriya Paroder, Mika Lin, Marissa Mattar, Juan Qiu, Qing Chang, Huiyong Zhao, Jonathan Zhang, Megan Little, Yuta Adachi, Sae-Won Han, Barry S. Taylor, Hiromichi Ebi, Omar Abdel-Wahab, Elisa de Stanchina, Charles M. Rudin, Pasi A. Jänne, Frank McCormick, Zhan Yao, Neal Rosen
    Mol Cell. Author manuscript; available in PMC 2023 Jul 7.
    Published in final edited form as: Mol Cell. 2022 Jul 7; 82(13): 2443–2457.e7. Published online 2022 May 24. doi: 10.1016/j.molcel.2022.04.034
    PMCID:
    PMC9271631
    AbstractArticlePDF–2.8M
    14.
    ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia
    Linjiang Lao, Isabelle Bourdeau, Lucia Gagliardi, Xiao He, Wei Shi, Bingbing Hao, Minjia Tan, Yan Hu, Junzheng Peng, Benoit Coulombe, David J Torpy, Hamish S Scott, Andre Lacroix, Hongyu Luo, Jiangping Wu
    Nucleic Acids Res. 2022 Jun 24; 50(11): 6343–6367. Published online 2022 Jun 10. doi: 10.1093/nar/gkac483
    PMCID:
    PMC9226510
    AbstractArticlePDF–3.7M
    15.
    OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
    Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
    Science. Author manuscript; available in PMC 2022 Sep 11.
    Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
    PMCID:
    PMC9119736
    AbstractArticlePDF–3.3M
    16.
    Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
    Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
    Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
    PMCID:
    PMC9105235
    AbstractArticlePDF–5.8M
    17.
    The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
    Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
    J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
    PMCID:
    PMC9058836
    AbstractArticlePDF–2.9M
    18.
    A protein interaction landscape of breast cancer
    Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
    Science. Author manuscript; available in PMC 2022 Apr 26.
    Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
    PMCID:
    PMC9040556
    AbstractArticlePDF–2.2M
    19.
    A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity
    Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan
    Science. Author manuscript; available in PMC 2022 Apr 13.
    Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911
    PMCID:
    PMC9005332
    AbstractArticlePDF–2.0M
    20.
    ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers
    Juliane Mooz, Kristina Riegel, Hari PS, Anguraj Sadanandam, Federico Marini, Matthias Klein, Ulrike Werner, Wilfried Roth, Annett Wilken-Schmitz, Irmgard Tegeder, Krishnaraj Rajalingam
    Sci Adv. 2022 Mar; 8(11): eabk1538. Published online 2022 Mar 18. doi: 10.1126/sciadv.abk1538
    PMCID:
    PMC8932670
    AbstractArticlePDF–2.2M

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