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Select item 113644181.

RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis

Zhenqiong Guan, Huiling Li, Chongtao Zhang, Ziyan Huang, Meidi Ye, Yulan Zhang, Shufen Li, Ke Peng

PLoS Pathog. 2024 Aug; 20(8): e1012387. Published online 2024 Aug 30. doi: 10.1371/journal.ppat.1012387

PMCID:: PMC11364418

Abstract Article PDF–3.7M

Select item 112969142.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 111470373.

Functional analysis of the human MCL-1 gene

C. Akgul, P. C. Turner, M. R. H. White, S. W. Edwards*

Cell Mol Life Sci. 2000 Apr; 57(4): 684–691. doi: 10.1007/PL00000728

PMCID:: PMC11147037

Abstract Article PDF–339K

Select item 111315504.

Mcl-1 is a potential therapeutic target in multiple types of cancer

C. Akgul

Cell Mol Life Sci. 2009 Apr; 66(8): 1326–1336. Published online 2008 Dec 16. doi: 10.1007/s00018-008-8637-6

PMCID:: PMC11131550

Abstract Article PDF–1.2M

Select item 110727485.

MCL1 alternative polyadenylation is essential for cell survival and mitochondria morphology

Isabel Pereira-Castro, Beatriz C. Garcia, Ana Curinha, Ana Neves-Costa, Eduardo Conde-Sousa, Luís F. Moita, Alexandra Moreira

Cell Mol Life Sci. 2022 Mar; 79(3): 164. Published online 2022 Mar 1. doi: 10.1007/s00018-022-04172-x

PMCID:: PMC11072748

Abstract Article PDF–9.0M

Select item 108995306.

Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization

Camille A. McAloney, Rawan Makkawi, Yogesh Budhathoki, Matthew V. Cannon, Emily M. Franz, Amy C. Gross, Maren Cam, Tatyana A. Vetter, Rebekka Duhen, Alexander E. Davies, Ryan D. Roberts

Cell Oncol (Dordr) 2024; 47(1): 259–282. Published online 2023 Sep 7. doi: 10.1007/s13402-023-00867-w

PMCID:: PMC10899530

Abstract Article PDF–3.9M

Select item 108160537.

Mcl-1 Protein and Viral Infections: A Narrative Review

Zbigniew Wyżewski, Justyna Stępkowska, Aleksandra Maria Kobylińska, Adriana Mielcarska, Matylda Barbara Mielcarska

Int J Mol Sci. 2024 Jan; 25(2): 1138. Published online 2024 Jan 17. doi: 10.3390/ijms25021138

PMCID:: PMC10816053

Abstract Article PDF–830K

Select item 105064198.

miR-181c regulates MCL1 and cell survival in GATA2 deficient cells

Weixin Wang, Rui Chen, Stephenie Droll, Emily Barber, Layla Saleh, Meghan Corrigan-Cummins, Megan Trick, Vollter Anastas, Nga Voong Hawk, Zhen Zhao, Donald C. Vinh, Amy Hsu, Dennis D. Hickstein, Steven M. Holland, Katherine R. Calvo

J Leukoc Biol. Author manuscript; available in PMC 2023 Sep 18.

Published in final edited form as: J Leukoc Biol. 2022 Apr; 111(4): 805–816. Published online 2021 Jul 16. doi: 10.1002/JLB.2A1220-824R

PMCID:: PMC10506419

Abstract Article PDF–1.4M

Select item 104607329.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 1039866010.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Abstract Article PDF–2.4M

Select item 1027947211.

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways

Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett

Cell Rep. Author manuscript; available in PMC 2023 Jun 19.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496

PMCID:: PMC10279472

Abstract Article PDF–2.9M

Select item 1024469812.

Polypyrimidine tract binding protein 1 (PTBP1) contains a novel regulatory sequence, the rBH3, that binds the prosurvival protein MCL1

Christine Carico, Jia Cui, Alexus Acton, William J. Placzek

J Biol Chem. 2023 Jun; 299(6): 104778. Published online 2023 May 3. doi: 10.1016/j.jbc.2023.104778

PMCID:: PMC10244698

Abstract Article PDF–1.5M

Select item 1023742213.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1016915014.

SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication

Pan Pan, Weiwei Ge, Zhiwei Lei, Wei luo, Yuqing Liu, Zhanwen Guan, Lumiao Chen, Zhenyang Yu, Miaomiao Shen, Dingwen Hu, Qi Xiang, Wenbiao Wang, Pin Wan, Mingfu Tian, Yang Yu, Zhen Luo, Xulin Chen, Heng Xiao, Qiwei Zhang, Xujing Liang, Xin Chen, Yongkui Li, Jianguo Wu

Signal Transduct Target Ther. 2023; 8: 194. Published online 2023 May 9. doi: 10.1038/s41392-023-01459-8

PMCID:: PMC10169150

Abstract Article PDF–6.6M

Select item 1014769715.

Dual targeting of BCL-2 and MCL-1 in the presence of BAX breaks venetoclax resistance in human small cell lung cancer

Zsuzsanna Valko, Zsolt Megyesfalvi, Anna Schwendenwein, Christian Lang, Sandor Paku, Nandor Barany, Bence Ferencz, Anita Horvath-Rozsas, Ildiko Kovacs, Erzsebet Schlegl, Veronika Pozonec, Kristiina Boettiger, Melinda Rezeli, Gyorgy Marko-Varga, Ferenc Renyi-Vamos, Mir Alireza Hoda, Thomas Klikovits, Konrad Hoetzenecker, Michael Grusch, Viktoria Laszlo, Balazs Dome, Karin Schelch

Br J Cancer. 2023 May 11; 128(10): 1850–1861. Published online 2023 Mar 14. doi: 10.1038/s41416-023-02219-9

PMCID:: PMC10147697

Abstract Article PDF–1.2M

Select item 997349616.

Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation

Yvonne J. Thus, Martin F.M. de Rooij, Nathalie Swier, Roderick L. Beijersbergen, Jeroen E.J. Guikema, Marie-José Kersten, Eric Eldering, Steven T. Pals, Arnon P. Kater, Marcel Spaargaren

Haematologica. 2023 Mar 1; 108(3): 797–810. Published online 2022 Oct 13. doi: 10.3324/haematol.2022.281668