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Items: 1 to 20 of 57

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis
Takenobu Ishii, Montserrat Ruiz‐Torruella, Jae Young Kim, Hiroyuki Kanzaki, Abdullah Albassam, Wichaya Wisitrasameewong, Satoru Shindo, Roodelyne Pierrelus, Alireza Heidari, Umadevi Kandalam, Shin Nakamura, Alexandru Movila, Dmitriy Minond, Toshihisa Kawai
J Cell Mol Med. 2023 Jun; 27(12): 1750–1756. Published online 2023 May 11. doi: 10.1111/jcmm.17416
PMCID:
PMC10273054
AbstractArticlePDF–1.5M
3.
Sema4D silencing increases the sensitivity of nivolumab to B16-F10 resistant melanoma via inhibiting the PI3K/AKT signaling pathway
Zhuo Zhang, Duoli Zhang, Fang Wang, Jiao Liu, Yuhong Sun, Songyot Anuchapreeda, Singkome Tima, Zhangang Xiao, Suwit Duangmano
PeerJ. 2023; 11: e15172. Published online 2023 Apr 19. doi: 10.7717/peerj.15172
PMCID:
PMC10122458
AbstractArticlePDF–11M
4.
Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity
Elizabeth E. Evans, Vikas Mishra, Crystal Mallow, Elaine M. Gersz, Leslie Balch, Alan Howell, Christine Reilly, Ernest S. Smith, Terrence L. Fisher, Maurice Zauderer
J Neuroinflammation. 2022; 19: 200. Published online 2022 Aug 6. doi: 10.1186/s12974-022-02509-8
PMCID:
PMC9356477
AbstractArticlePDF–2.1M
5.
Anti-Semaphorin 4D Rescues Motor, Cognitive, and Respiratory Phenotypes in a Rett Syndrome Mouse Model
Yilin Mao, Elizabeth E. Evans, Vikas Mishra, Leslie Balch, Allison Eberhardt, Maurice Zauderer, Wendy A. Gold
Int J Mol Sci. 2021 Sep; 22(17): 9465. Published online 2021 Aug 31. doi: 10.3390/ijms22179465
PMCID:
PMC8431088
AbstractArticlePDF–2.5M
6.
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects
Hélène Choquet, Ronald B. Melles, Deepti Anand, Jie Yin, Gabriel Cuellar-Partida, Wei Wang, 23andMe Research Team, Thomas J. Hoffmann, K. Saidas Nair, Pirro G. Hysi, Salil A. Lachke, Eric Jorgenson
Nat Commun. 2021; 12: 3595. Published online 2021 Jun 14. doi: 10.1038/s41467-021-23873-8
PMCID:
PMC8203611
AbstractArticlePDF–1.9M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy
Jie‐hong Wu, Ya‐nan Li, An‐qi Chen, Can‐dong Hong, Chun‐lin Zhang, Hai‐ling Wang, Yi‐fan Zhou, Peng‐Cheng Li, Yong Wang, Ling Mao, Yuan‐peng Xia, Quan‐wei He, Hui‐juan Jin, Zhen‐yu Yue, Bo Hu
EMBO Mol Med. 2020 Feb 7; 12(2): e10154. Published online 2020 Jan 13. doi: 10.15252/emmm.201810154
PMCID:
PMC7005627
AbstractArticlePDF–5.2M
9.
Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D
Jianguo Huang, Mark Chen, Eric S. Xu, Lixia Luo, Yan Ma, Wesley Huang, Warren Floyd, Tyler S. Klann, So Young Kim, Charles A. Gersbach, Diana M. Cardona, David G. Kirsch
Sci Rep. 2019; 9: 17220. Published online 2019 Nov 20. doi: 10.1038/s41598-019-53572-w
PMCID:
PMC6868134
AbstractArticlePDF–2.9M
10.
The Transmembrane Semaphorin Sema4D/CD100, an Inhibitor of Axonal Growth, Is Expressed on Oligodendrocytes and Upregulated after CNS Lesion
Caroline Moreau-Fauvarque, Atsushi Kumanogoh, Emeline Camand, Céline Jaillard, Gilles Barbin, Isabelle Boquet, Christopher Love, E. Yvonne Jones, Hitoshi Kikutani, Catherine Lubetzki, Isabelle Dusart, Alain Chédotal
J Neurosci. 2003 Oct 8; 23(27): 9229–9239. doi: 10.1523/JNEUROSCI.23-27-09229.2003
PMCID:
PMC6740837
AbstractArticlePDF–1.0M
11.
Plexin-B2 Controls the Development of Cerebellar Granule Cells
Roland H. Friedel, Géraldine Kerjan, Helen Rayburn, Ulrich Schüller, Constantino Sotelo, Marc Tessier-Lavigne, Alain Chédotal
J Neurosci. 2007 Apr 4; 27(14): 3921–3932. doi: 10.1523/JNEUROSCI.4710-06.2007
PMCID:
PMC6672405
AbstractArticlePDF–911K
12.
Plexin-B2, But Not Plexin-B1, Critically Modulates Neuronal Migration and Patterning of the Developing Nervous System In Vivo
Suhua Deng, Alexandra Hirschberg, Thomas Worzfeld, Junia Y. Penachioni, Alexander Korostylev, Jakub M. Swiercz, Peter Vodrazka, Olivier Mauti, Esther T. Stoeckli, Luca Tamagnone, Stefan Offermanns, Rohini Kuner
J Neurosci. 2007 Jun 6; 27(23): 6333–6347. doi: 10.1523/JNEUROSCI.5381-06.2007
PMCID:
PMC6672150
AbstractArticlePDF–1.1M
13.
Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation
Stephanie LaHaye, Uddalak Majumdar, Jun Yasuhara, Sara N. Koenig, Adrianna Matos-Nieves, Rahul Kumar, Vidu Garg
Dis Model Mech. 2019 Jun 1; 12(6): dmm036764. Published online 2019 Jun 24. doi: 10.1242/dmm.036764
PMCID:
PMC6602309
AbstractArticle
14.
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System
Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund
Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005
PMCID:
PMC6381388
AbstractArticle
15.
Class 4 Semaphorins and Plexin-B receptors regulate GABAergic and glutamatergic synapse development in the mammalian hippocampus
Jacqueline E. McDermott, Dena Goldblatt, Suzanne Paradis
Mol Cell Neurosci. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Mol Cell Neurosci. 2018 Oct; 92: 50–66. Published online 2018 Jul 4. doi: 10.1016/j.mcn.2018.06.008
PMCID:
PMC6191356
AbstractArticlePDF–1.5M
16.
Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D
Kou Motani, Hidetaka Kosako
J Biol Chem. 2018 May 18; 293(20): 7717–7726. Published online 2018 Apr 4. doi: 10.1074/jbc.RA118.002175
PMCID:
PMC5961039
AbstractArticlePDF–1.4M
17.
Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis
Masayuki Nishide, Satoshi Nojima, Daisuke Ito, Hyota Takamatsu, Shohei Koyama, Sujin Kang, Tetsuya Kimura, Keiko Morimoto, Takashi Hosokawa, Yoshitomo Hayama, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Yoshimitsu Nakanishi, Takeshi Tsuda, Jeong Hoon Park, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Eiichi Morii, Atsushi Kumanogoh
Ann Rheum Dis. 2017 Aug; 76(8): 1440–1448. Published online 2017 Apr 17. doi: 10.1136/annrheumdis-2016-210706
PMCID:
PMC5738596
AbstractArticlePDF–3.0M
18.
Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells
Ayelen Bulloj, Arvydas Maminishkis, Masayuki Mizui, Silvia C. Finnemann
Mol Neurobiol. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Mol Neurobiol. 2018 May; 55(5): 4320–4332. Published online 2017 Jun 17. doi: 10.1007/s12035-017-0649-5
PMCID:
PMC5733634
AbstractArticlePDF–3.0M
19.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
20.
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina
Jasper J Visser, Yolanda Cheng, Steven C Perry, Andrew Benjamin Chastain, Bayan Parsa, Shatha S Masri, Thomas A Ray, Jeremy N Kay, Woj M Wojtowicz
eLife. 2015; 4: e08149. Published online 2015 Dec 2. doi: 10.7554/eLife.08149
PMCID:
PMC4737655
AbstractArticlePDF–4.2M

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