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Select item 103631201.

LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis

Dan-Pei Li, Li Huang, Ran-Ran Kan, Xiao-Yu Meng, Shu-Yun Wang, Hua-Jie Zou, Ya-Ming Guo, Pei-Qiong Luo, Li-Meng Pan, Yu-Xi Xiang, Bei-Bei Mao, Yu-Yu Xie, Zhi-Han Wang, Min Yang, Rui He, Yan Yang, Zhe-Long Liu, Jun-Hui Xie, De-Lin Ma, Ben-Ping Zhang, Shi-Ying Shao, Xi Chen, Si-Miao Xu, Wen-Tao He, Wen-Jun Li, Yong Chen, Xue-Feng Yu

Nat Commun. 2023; 14: 4436. Published online 2023 Jul 22. doi: 10.1038/s41467-023-40183-3

PMCID:: PMC10363120

Abstract Article PDF–8.3M

Select item 93265092.

Placental Malaria is Associated with Higher LILRB2 Expression in Monocyte Subsets and Lower Anti-Malarial IgG Antibodies During Infancy

Celia Dechavanne, Odilon Nouatin, Rafiou Adamou, Sofie Edslev, Anita Hansen, Florian Meurisse, Ibrahim Sadissou, Erasme Gbaguidi, Jacqueline Milet, Gilles Cottrell, Laure Gineau, Audrey Sabbagh, Achille Massougbodji, Kabirou Moutairou, Eduardo A. Donadi, Edgardo D. Carosella, Philippe Moreau, Ed Remarque, Michael Theisen, Nathalie Rouas-Freiss, André Garcia, Benoit Favier, David Courtin

Front Immunol. 2022; 13: 909831. Published online 2022 Jul 12. doi: 10.3389/fimmu.2022.909831

PMCID:: PMC9326509

Abstract Article PDF–2.9M

Select item 92295933.

Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill Mycobacterium tuberculosis

Vipul K. Singh, Arshad Khan, Yitian Xu, Sunny Mai, Licheng Zhang, Abhishek Mishra, Blanca I. Restrepo, Ping-Ying Pan, Shu-Hsia Chen, Chinnaswamy Jagannath

Front Immunol. 2022; 13: 865503. Published online 2022 Jun 10. doi: 10.3389/fimmu.2022.865503

PMCID:: PMC9229593

Abstract Article PDF–5.5M

Select item 92063874.

LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu, Timothy Y. Huang, Yingjun Zhao, Chengcheng Zhang, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An

Mol Neurodegener. 2022; 17: 44. Published online 2022 Jun 18. doi: 10.1186/s13024-022-00550-y

PMCID:: PMC9206387

Abstract Article PDF–11M

Select item 86173735.

Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2

Yunqing Gu, Jun Cao, Xinyu Zhang, Hai Gao, Yuyan Wang, Jia Wang, Juan He, Xiaoyi Jiang, Jinlan Zhang, Guanghui Shen, Jie Yang, Xichen Zheng, Gaowei Hu, Yuanfei Zhu, Shujuan Du, Yunkai Zhu, Rong Zhang, Jianqing Xu, Fei Lan, Di Qu, Guoliang Xu, Yun Zhao, Dong Gao, Youhua Xie, Min Luo, Zhigang Lu

Cell Res. 2022 Jan; 32(1): 24–37. Published online 2021 Nov 26. doi: 10.1038/s41422-021-00595-6

Correction in:: Cell Res. 2022 Jun; 32(6): 600.

PMCID:: PMC8617373

Abstract Article PDF–5.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81556017.

Prognostic Significance of Immune Checkpoints HLA-G/ILT-2/4 and PD-L1 in Colorectal Cancer

Qiong-Yuan Chen, Yu-Xin Chen, Qiu-Yue Han, Jiang-Gang Zhang, Wen-Jun Zhou, Xia Zhang, Yao-Han Ye, Wei-Hua Yan, Aifen Lin

Front Immunol. 2021; 12: 679090. Published online 2021 May 13. doi: 10.3389/fimmu.2021.679090

PMCID:: PMC8155601

Abstract Article PDF–2.5M

Select item 79298058.

Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity

Aiqin Gao, Xia Liu, Wenli Lin, Jingnan Wang, Shuyun Wang, Fusheng Si, Lan Huang, Yangjing Zhao, Yuping Sun, Guangyong Peng

J Immunother Cancer. 2021; 9(3): e001536. Published online 2021 Mar 2. doi: 10.1136/jitc-2020-001536

PMCID:: PMC7929805

Abstract Article PDF–7.7M

Select item 78476669.

ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation

Xiaozheng Chen, Aiqin Gao, Fang Zhang, Zijiang Yang, Shuyun Wang, Yuying Fang, Juan Li, Jingnan Wang, Wenjing Shi, Linlin Wang, Yan Zheng, Yuping Sun

Theranostics. 2021; 11(7): 3392–3416. Published online 2021 Jan 19. doi: 10.7150/thno.52435

PMCID:: PMC7847666

Abstract Article PDF–5.1M

Select item 733341110.

The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma

Marcela García, Maria Belen Palma, Jerome Verine, Santiago Miriuka, Ana M. Inda, Ana L. Errecalde, François Desgrandchamps, Edgardo D. Carosella, Diana Tronik-Le Roux

BMC Cancer. 2020; 20: 624. Published online 2020 Jul 3. doi: 10.1186/s12885-020-07113-8

PMCID:: PMC7333411

Abstract Article PDF–2.4M

Select item 724793811.

The Interaction of LILRB2 with HLA-B is Associated with Psoriasis Susceptibility

Rebecca L. Yanovsky, Haoyan Chen, Stephen Leslie, Mary Carrington, Wilson Liao

J Invest Dermatol. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: J Invest Dermatol. 2020 Jun; 140(6): 1292–1295.e3. Published online 2019 Dec 24. doi: 10.1016/j.jid.2019.12.006

PMCID:: PMC7247938

Article PDF–57K

Select item 652194012.

Immunoglobulin-like transcript 4 and human leukocyte antigen-G interaction promotes the progression of human colorectal cancer

Zhaoyang Cai, Lu Wang, Yali Han, Wenwen Gao, Xiaojuan Wei, Rumei Gong, Mingliang Zhu, Yuping Sun, Shuwen Yu

Int J Oncol. 2019 Jun; 54(6): 1943–1954. Published online 2019 Mar 22. doi: 10.3892/ijo.2019.4761

PMCID:: PMC6521940

Abstract Article PDF–2.0M

Select item 594826613.

The impact of HLA-G, LILRB1 and LILRB2 gene polymorphisms on susceptibility to and severity of endometriosis

Aleksandra Bylińska, Karolina Wilczyńska, Jacek Malejczyk, Łukasz Milewski, Marta Wagner, Monika Jasek, Wanda Niepiekło-Miniewska, Andrzej Wiśniewski, Rafał Płoski, Ewa Barcz, Piotr Roszkowski, Paweł Kamiński, Andrzej Malinowski, Jacek R. Wilczyński, Paweł Radwan, Michał Radwan, Piotr Kuśnierczyk, Izabela Nowak

Mol Genet Genomics. 2018; 293(3): 601–613. Published online 2017 Dec 12. doi: 10.1007/s00438-017-1404-3

PMCID:: PMC5948266

Abstract Article PDF–978K

Select item 582186814.

Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4

Ning Lu, Ying Li, Zhiqiang Zhang, Junji Xing, Ying Sun, Sheng Yao, Lieping Chen

Nat Commun. 2018; 9: 742. Published online 2018 Feb 21. doi: 10.1038/s41467-018-03128-9

PMCID:: PMC5821868

Abstract Article PDF–1.9M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 502989516.

HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1

Aura Burian, Kevin L. Wang, Kathryn A. K. Finton, Ni Lee, Akiko Ishitani, Roland K. Strong, Daniel E. Geraghty

PLoS One. 2016; 11(9): e0163297. Published online 2016 Sep 20. doi: 10.1371/journal.pone.0163297

PMCID:: PMC5029895

Abstract Article PDF–2.1M

Select item 487543417.

Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding

Gol Nam, Yi Shi, Myongchol Ryu, Qihui Wang, Hao Song, Jun Liu, Jinghua Yan, Jianxun Qi, George F. Gao

Protein Cell. 2013 Oct; 4(10): 761–770. Published online 2013 Aug 17. doi: 10.1007/s13238-013-3908-x

PMCID:: PMC4875434

Abstract Article PDF–4.0M

Select item 477982018.

Analysis of the Expression and Function of Immunoglobulin-Like Transcript 4 (ILT4, LILRB2) in Dendritic Cells from Patients with Systemic Lupus Erythematosus

Paola del Carmen Guerra-de Blas, Yael Sebastián Villaseñor-Talavera, Daniela de Jesús Cruz-González, Lourdes Baranda, Lesly Doníz-Padilla, Carlos Abud-Mendoza, Roberto González-Amaro, Adriana Elizabeth Monsiváis-Urenda

J Immunol Res. 2016; 2016: 4163094. Published online 2016 Feb 22. doi: 10.1155/2016/4163094

PMCID:: PMC4779820

Abstract Article PDF–1.7M

Select item 467324619.

ANGPTL2/LILRB2 signaling promotes the propagation of lung cancer cells

Xiaoye Liu, Xiaoting Yu, Jingjing Xie, Mengna Zhan, Zhuo Yu, Li Xie, Hongxiang Zeng, Feifei Zhang, Guoqiang Chen, Xianghua Yi, Junke Zheng

Oncotarget. 2015 Aug 28; 6(25): 21004–21015. Published online 2015 May 20. doi: 10.18632/oncotarget.4217

PMCID:: PMC4673246

Abstract Article PDF–10M

Select item 461721120.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

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