PMC Links for GEO Profiles (Select 108548155) - PMC

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76851734.

HIV and opiates dysregulate K⁺-Cl⁻ cotransporter 2 (KCC2) to cause GABAergic dysfunction in primary human neurons and Tat-transgenic mice

Aaron J. Barbour, Kurt F. Hauser, A. Rory McQuiston, Pamela E. Knapp

Neurobiol Dis. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Neurobiol Dis. 2020 Jul; 141: 104878. Published online 2020 Apr 25. doi: 10.1016/j.nbd.2020.104878

PMCID:: PMC7685173

Abstract Article PDF–2.3M

Select item 75627435.

Environmental regulation of the chloride transporter KCC2: switching inflammation off to switch the GABA on?

Davide Pozzi, Marco Rasile, Irene Corradini, Michela Matteoli

Transl Psychiatry. 2020; 10: 349. Published online 2020 Oct 15. doi: 10.1038/s41398-020-01027-6

PMCID:: PMC7562743

Abstract Article PDF–689K

Select item 71322016.

Loss of non‐canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons

Martina Mavrovic, Pavel Uvarov, Eric Delpire, Laszlo Vutskits, Kai Kaila, Martin Puskarjov

EMBO Rep. 2020 Apr 3; 21(4): e48880. Published online 2020 Feb 17. doi: 10.15252/embr.201948880

PMCID:: PMC7132201

Abstract Article PDF–5.7M

Select item 69175137.

Sequence Variation Associated with SLC12A5 Gene Expression Is Linked to Brain Structure and Function in Healthy Adults

Michael D Gregory, J Shane Kippenhan, Joseph H Callicott, Daniel Y Rubinstein, Venkata S Mattay, Richard Coppola, Karen F Berman

Cereb Cortex. 2019 Dec; 29(11): 4654–4661. Published online 2019 Jan 21. doi: 10.1093/cercor/bhy344

PMCID:: PMC6917513

Abstract Article PDF–647K

Select item 68922408.

KCC2 expression levels are reduced in post mortem brain tissue of Rett syndrome patients

Lisa Hinz, Joan Torrella Barrufet, Vivi M. Heine

Acta Neuropathol Commun. 2019; 7: 196. Published online 2019 Dec 3. doi: 10.1186/s40478-019-0852-x

PMCID:: PMC6892240

Abstract Article PDF–852K

Select item 62315449.

Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model

Anatoly Buchin, Anton Chizhov, Gilles Huberfeld, Richard Miles, Boris S. Gutkin

J Neurosci. 2016 Nov 16; 36(46): 11619–11633. doi: 10.1523/JNEUROSCI.4228-15.2016

PMCID:: PMC6231544

Abstract Article PDF–5.2M

Select item 622210310.

Phosphoregulation of the intracellular termini of K⁺-Cl⁻ cotransporter 2 (KCC2) enables flexible control of its activity

Antje Cordshagen, Wiebke Busch, Michael Winklhofer, Hans Gerd Nothwang, Anna-Maria Hartmann

J Biol Chem. 2018 Nov 2; 293(44): 16984–16993. Published online 2018 Sep 10. doi: 10.1074/jbc.RA118.004349

Correction in:: J Biol Chem. 2020 Aug 14; 295(33): 11948.

PMCID:: PMC6222103

Abstract Article PDF–1.2M

Select item 616668211.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 543176013.

The neuronal K⁺Cl⁻ co-transporter 2 (Slc12a5) modulates insulin secretion

Shams Kursan, Timothy S. McMillen, Pavani Beesetty, Eduardo Dias-Junior, Mohammed M. Almutairi, Abu A. Sajib, J. Ashot Kozak, Lydia Aguilar-Bryan, Mauricio Di Fulvio

Sci Rep. 2017; 7: 1732. Published online 2017 May 11. doi: 10.1038/s41598-017-01814-0

PMCID:: PMC5431760

Abstract Article PDF–4.9M

Select item 538652414.

Solute carrier family 12 member 5 promotes tumor invasion/metastasis of bladder urothelial carcinoma by enhancing NF-κB/MMP-7 signaling pathway

J Y Liu, Y B Dai, X Li, K Cao, D Xie, Z T Tong, Z Long, H Xiao, M K Chen, Y L Ye, B Liu, J Tan, J Tang, Z Z Xu, Y Gan, Y H Zhou, F Deng, L Y He

Cell Death Dis. 2017 Mar; 8(3): e2691. Published online 2017 Mar 23. doi: 10.1038/cddis.2017.118

PMCID:: PMC5386524

Abstract Article PDF–2.4M

Select item 537173015.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 522492416.

APP modulates KCC2 expression and function in hippocampal GABAergic inhibition

Ming Chen, Jinzhao Wang, Jinxiang Jiang, Xingzhi Zheng, Nicholas J Justice, Kun Wang, Xiangqian Ran, Yi Li, Qingwei Huo, Jiajia Zhang, Hongmei Li, Nannan Lu, Ying Wang, Hui Zheng, Cheng Long, Li Yang

eLife. 2017; 6: e20142. Published online 2017 Jan 5. doi: 10.7554/eLife.20142

PMCID:: PMC5224924

Abstract Article PDF–6.3M

Select item 495181217.

Impaired neuronal KCC2 function by biallelic SLC12A5 mutations in migrating focal seizures and severe developmental delay

Hirotomo Saitsu, Miho Watanabe, Tenpei Akita, Chihiro Ohba, Kenji Sugai, Winnie Peitee Ong, Hideaki Shiraishi, Shota Yuasa, Hiroshi Matsumoto, Khoo Teik Beng, Shinji Saitoh, Satoko Miyatake, Mitsuko Nakashima, Noriko Miyake, Mitsuhiro Kato, Atsuo Fukuda, Naomichi Matsumoto

Sci Rep. 2016; 6: 30072. Published online 2016 Jul 20. doi: 10.1038/srep30072

PMCID:: PMC4951812

Abstract Article PDF–1.9M

Select item 481960918.

Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer

Lixia Xu, Xiaoxing Li, Muyan Cai, Jinna Chen, Xiangchun Li, William K K Wu, Wei Kang, Joanna Tong, Ka-Fai To, Xin-Yuan Guan, Joseph J Y Sung, Francis K L Chan, Jun Yu

Gut. 2016 Apr; 65(4): 635–646. Published online 2015 May 6. doi: 10.1136/gutjnl-2014-308257

PMCID:: PMC4819609

Abstract Article PDF–7.3M

Select item 472552319.

KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome

Xin Tang, Julie Kim, Li Zhou, Eric Wengert, Lei Zhang, Zheng Wu, Cassiano Carromeu, Alysson R. Muotri, Maria C. N. Marchetto, Fred H. Gage, Gong Chen

Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3): 751–756. Published online 2016 Jan 5. doi: 10.1073/pnas.1524013113

PMCID:: PMC4725523

Abstract Article PDF–1.4M

Select item 461721120.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

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