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Items: 1 to 20 of 21

1.
Functional AGXT2 SNP rs180749 variant and depressive symptoms: Baseline data from the Aidai Cohort Study in Japan
Hiroshi Kumon, Yoshihiro Miyake, Yuta Yoshino, Jun-ichi Iga, Keiko Tanaka, Hidenori Senba, Eizen Kimura, Takashi Higaki, Bunzo Matsuura, Ryuichi Kawamoto, Shu-ichi Ueno
J Neural Transm (Vienna) 2024; 131(3): 267–274. Published online 2024 Jan 23. doi: 10.1007/s00702-024-02742-w
PMCID:
PMC10874328
AbstractArticlePDF–666K
2.
Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment
Einat Granot-Hershkovitz, Brian Spitzer, Yunju Yang, Wassim Tarraf, Bing Yu, Eric Boerwinkle, Myriam Fornage, Thomas H. Mosley, Charles DeCarli, Bruce S. Kristal, Hector M. González, Tamar Sofer
Transl Psychiatry. 2023; 13: 140. Published online 2023 Apr 29. doi: 10.1038/s41398-023-02437-y
PMCID:
PMC10148805
AbstractArticlePDF–1.1M
3.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001
PMCID:
PMC8664129
AbstractArticle
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Effects of AGXT2 variants on blood pressure and blood sugar among 750 older Japanese subjects recruited by the complete enumeration survey method
Yuta Yoshino, Hiroshi Kumon, Takaaki Mori, Taku Yoshida, Ayumi Tachibana, Hideaki Shimizu, Jun-ichi Iga, Shu-ichi Ueno
BMC Genomics. 2021; 22: 287. Published online 2021 Apr 20. doi: 10.1186/s12864-021-07612-3
PMCID:
PMC8059213
AbstractArticlePDF–716K
6.
The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex
Wentao Zhang, Ning Duan, Qian Zhang, Tao Song, Zhong Li, Xun Chen, Kunzheng Wang
Int J Biol Sci. 2018; 14(14): 2023–2036. Published online 2018 Nov 3. doi: 10.7150/ijbs.28302
PMCID:
PMC6299368
AbstractArticlePDF–2.0M
7.
A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2
Roman N. Rodionov, Elisa Oppici, Jens Martens-Lobenhoffer, Natalia Jarzebska, Silke Brilloff, Dmitrii Burdin, Anton Demyanov, Anne Kolouschek, James Leiper, Renke Maas, Barbara Cellini, Norbert Weiss, Stefanie M. Bode-Böger
Sci Rep. 2016; 6: 35277. Published online 2016 Oct 18. doi: 10.1038/srep35277
PMCID:
PMC5082758
AbstractArticlePDF–1.1M
8.
Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine
Nicole Lüneburg, Wolfgang Lieb, Tanja Zeller, Ming-Huei Chen, Renke Maas, Angela M. Carter, Vanessa Xanthakis, Nicole L Glazer, Edzard Schwedhelm, Sudha Seshadri, M. Arfan Ikram, W.T. Longstreth, Jr, Myriam Fornage, Inke R. König, Christina Loley, Francisco M. Ojeda, Arne Schillert, Thomas J. Wang, Heinrich Sticht, Anja Kittel, Jörg König, Emelia J. Benjamin, Lisa M. Sullivan, Isabel Bernges, Maike Anderssohn, Andreas Ziegler, Christian Gieger, Thomas Illig, Christa Meisinger, H.-Erich Wichmann, Philipp S. Wild, Heribert Schunkert, Bruce M. Psaty, Kerri L. Wiggins, Susan R. Heckbert, Nicholas Smith, Karl Lackner, Kathryn L. Lunetta, Stefan Blankenberg, Jeanette Erdmann, Thomas Munzel, Peter J. Grant, Ramachandran S. Vasan, Rainer H. Böger
Circ Cardiovasc Genet. Author manuscript; available in PMC 2016 Mar 18.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Dec; 7(6): 864–872. Published online 2014 Sep 21. doi: 10.1161/CIRCGENETICS.113.000264
PMCID:
PMC4797637
AbstractArticlePDF–2.2M
9.
Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke
Ilkka Seppälä, Marcus E. Kleber, Steve Bevan, Leo-Pekka Lyytikäinen, Niku Oksala, Jussi A. Hernesniemi, Kari-Matti Mäkelä, Peter M. Rothwell, Cathie Sudlow, Martin Dichgans, Nina Mononen, Efthymia Vlachopoulou, Juha Sinisalo, Graciela E. Delgado, Reijo Laaksonen, Tuomas Koskinen, Hubert Scharnagl, Mika Kähönen, Hugh S. Markus, Winfried März, Terho Lehtimäki
Sci Rep. 2016; 6: 23207. Published online 2016 Mar 17. doi: 10.1038/srep23207
PMCID:
PMC4794714
AbstractArticlePDF–781K
10.
AGXT2: a promiscuous aminotransferase
Roman N. Rodionov, Natalia Jarzebska, Norbert Weiss, Steven R. Lentz
Trends Pharmacol Sci. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Trends Pharmacol Sci. 2014 Nov; 35(11): 575–582. Published online 2014 Oct 13. doi: 10.1016/j.tips.2014.09.005
PMCID:
PMC4254113
AbstractArticlePDF–1.0M
11.
A Genome-Wide Association Study of the Human Metabolome in a Community-Based Cohort
Eugene P. Rhee, Jennifer E. Ho, Ming-Huei Chen, Dongxiao Shen, Susan Cheng, Martin G. Larson, Anahita Ghorbani, Xu Shi, Iiro T. Helenius, Christopher J. O’Donnell, Amanda L. Souza, Amy Deik, Kerry A. Pierce, Kevin Bullock, Geoffrey A. Walford, Ramachandran S. Vasan, Jose C. Florez, Clary Clish, J.-R. Joanna Yeh, Thomas J. Wang, Robert E. Gerszten
Cell Metab. Author manuscript; available in PMC 2014 Apr 2.
Published in final edited form as: Cell Metab. 2013 Jul 2; 18(1): 130–143. doi: 10.1016/j.cmet.2013.06.013
PMCID:
PMC3973158
AbstractArticlePDF–3.5M
12.
Alanine-glyoxylate aminotransferase 2 (AGXT2) Polymorphisms Have Considerable Impact on Methylarginine and β-aminoisobutyrate Metabolism in Healthy Volunteers
Anja Kittel, Fabian Müller, Jörg König, Maren Mieth, Heinrich Sticht, Oliver Zolk, Ana Kralj, Markus R. Heinrich, Martin F. Fromm, Renke Maas
PLoS One. 2014; 9(2): e88544. Published online 2014 Feb 24. doi: 10.1371/journal.pone.0088544
PMCID:
PMC3933329
AbstractArticlePDF–3.4M
13.
Genome-Wide Association Study of Metabolic Traits Reveals Novel Gene-Metabolite-Disease Links
Rico Rueedi, Mirko Ledda, Andrew W. Nicholls, Reza M. Salek, Pedro Marques-Vidal, Edgard Morya, Koichi Sameshima, Ivan Montoliu, Laeticia Da Silva, Sebastiano Collino, François-Pierre Martin, Serge Rezzi, Christoph Steinbeck, Dawn M. Waterworth, Gérard Waeber, Peter Vollenweider, Jacques S. Beckmann, Johannes Le Coutre, Vincent Mooser, Sven Bergmann, Ulrich K. Genick, Zoltán Kutalik
PLoS Genet. 2014 Feb; 10(2): e1004132. Published online 2014 Feb 20. doi: 10.1371/journal.pgen.1004132
PMCID:
PMC3930510
AbstractArticlePDF–491K
14.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection
George Nicholson, Mattias Rantalainen, Jia V. Li, Anthony D. Maher, Daniel Malmodin, Kourosh R. Ahmadi, Johan H. Faber, Amy Barrett, Josine L. Min, N. William Rayner, Henrik Toft, Maria Krestyaninova, Juris Viksna, Sudeshna Guha Neogi, Marc-Emmanuel Dumas, Ugis Sarkans, The MolPAGE Consortium, Peter Donnelly, Thomas Illig, Jerzy Adamski, Karsten Suhre, Maxine Allen, Krina T. Zondervan, Tim D. Spector, Jeremy K. Nicholson, John C. Lindon, Dorrit Baunsgaard, Elaine Holmes, Mark I. McCarthy, Chris C. Holmes
PLoS Genet. 2011 Sep; 7(9): e1002270. Published online 2011 Sep 8. doi: 10.1371/journal.pgen.1002270
PMCID:
PMC3169529
AbstractArticlePDF–1016K
17.
Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression
Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien
PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862
PMCID:
PMC2943476
AbstractArticlePDF–461K
18.
Human Alanine-Glyoxylate Aminotransferase 2 Lowers Asymmetric Dimethylarginine and Protects from Inhibition of Nitric Oxide Production
Roman N. Rodionov, Daryl J. Murry, Sarah F. Vaulman, Jeff W. Stevens, Steven R. Lentz
J Biol Chem. 2010 Feb 19; 285(8): 5385–5391. Published online 2009 Dec 14. doi: 10.1074/jbc.M109.091280
PMCID:
PMC2820767
AbstractArticlePDF–1.9M
19.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
20.
Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions
Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano
Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604
PMCID:
PMC515316
AbstractArticlePDF–181K

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