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Items: 1 to 20 of 97

1.
MiR-4465-modified mesenchymal stem cell-derived small extracellular vesicles inhibit liver fibrosis development via targeting LOXL2 expression
Yanjin WANG, Yifei CHEN, Fuji YANG, Xiaolong YU, Ying CHU, Jing ZHOU, Yongmin YAN, Jianbo XI
J Zhejiang Univ Sci B. 2024 Jul 16; 25(7): 594–604. Published online 2024 May 17. doi: 10.1631/jzus.B2300305
PMCID:
PMC11254680
AbstractArticlePDF–3.1M
2.
The role of LOXL2 induced by glucose metabolism-activated NF-κB in maintaining drug resistance through EMT and cancer stemness in gemcitabine-resistant PDAC
Yun Sun Lee, Hyung Sun Kim, Hyo Jung Kim, Hyeon Woong Kang, Da Eun Lee, Myeong Jin Kim, Woosol Chris Hong, Ju Hyun Kim, Minsoo Kim, Jae-Ho Cheong, Joon Seong Park
J Mol Med (Berl) 2023; 101(11): 1449–1464. Published online 2023 Sep 22. doi: 10.1007/s00109-023-02369-6
PMCID:
PMC10663195
AbstractArticlePDF–2.0M
3.
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival
Ezgi Ozyerli-Goknar, Ezgi Yagmur Kala, Ali Cenk Aksu, Ipek Bulut, Ahmet Cingöz, Sheikh Nizamuddin, Martin Biniossek, Fidan Seker-Polat, Tunc Morova, Can Aztekin, Sonia H. Y. Kung, Hamzah Syed, Nurcan Tuncbag, Mehmet Gönen, Martin Philpott, Adam P. Cribbs, Ceyda Acilan, Nathan A. Lack, Tamer T. Onder, H. T. Marc Timmers, Tugba Bagci-Onder
Cell Commun Signal. 2023; 21: 328. Published online 2023 Nov 16. doi: 10.1186/s12964-023-01335-6
PMCID:
PMC10652464
AbstractArticlePDF–8.0M
4.
Lysyl oxidase like-2 in fibrosis and cardiovascular disease
Alan Poe, Marta Martinez Yus, Huilei Wang, Lakshmi Santhanam
Am J Physiol Cell Physiol. 2023 Sep 1; 325(3): C694–C707. Published online 2023 Jun 17. doi: 10.1152/ajpcell.00176.2023
PMCID:
PMC10635644
AbstractArticle
5.
Lysyl oxidase‐like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3
Yi‐Jie Lu, Yi‐Ting Deng, Hui‐Hsin Ko, Hsin‐Hui Peng, Hsiang‐Chieh Lee, Mark Yen‐Ping Kuo, Shih‐Jung Cheng
Cancer Sci. 2023 Oct; 114(10): 3957–3971. Published online 2023 Jul 26. doi: 10.1111/cas.15912
PMCID:
PMC10551584
AbstractArticlePDF–48M
6.
The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4
Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang
Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5
PMCID:
PMC10460732
AbstractArticlePDF–5.6M
7.
Multiple Roles of LOXL2 in the Progression of Hepatocellular Carcinoma and Its Potential for Therapeutic Targeting
Jelena Radić, Bojana Kožik, Ivan Nikolić, Ivana Kolarov-Bjelobrk, Tijana Vasiljević, Bojana Vranjković, Sanja Despotović
Int J Mol Sci. 2023 Jul; 24(14): 11745. Published online 2023 Jul 21. doi: 10.3390/ijms241411745
PMCID:
PMC10380739
AbstractArticlePDF–1.1M
8.
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer
Zhize Qiu, Shiqi Qiu, Wenli Mao, Wu Lin, Qiqi Peng, Hao Chang
Exp Biol Med (Maywood) 2023 Mar; 248(6): 457–468. Published online 2022 Dec 27. doi: 10.1177/15353702221139203
PMCID:
PMC10281539
AbstractArticlePDF–5.4M
9.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
10.
Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma
Marta Alonso-Nocelo, Laura Ruiz-Cañas, Patricia Sancho, Kıvanç Görgülü, Sonia Alcalá, Coral Pedrero, Mireia Vallespinos, Juan Carlos López-Gil, Marina Ochando, Elena García-García, Sara Maria David Trabulo, Paola Martinelli, Patricia Sánchez-Tomero, Carmen Sánchez-Palomo, Patricia Gonzalez-Santamaría, Lourdes Yuste, Sonja Maria Wörmann, Derya Kabacaoğlu, Julie Earl, Alberto Martin, Fernando Salvador, Sandra Valle, Laura Martin-Hijano, Alfredo Carrato, Mert Erkan, Laura García-Bermejo, Patrick C Hermann, Hana Algül, Gema Moreno-Bueno, Christopher Heeschen, Francisco Portillo, Amparo Cano, Bruno Sainz, Jr
Gut. 2023 Feb; 72(2): 345–359. Published online 2022 Apr 15. doi: 10.1136/gutjnl-2021-325564
Correction in:
Gut. 2024 Oct; 73(10): e21.
PMCID:
PMC9872246
AbstractArticlePDF–11M
11.
Inhibition of lysyl oxidase‐like 2 overcomes adhesion‐dependent drug resistance in the collagen‐enriched liver cancer microenvironment
Lanqi Gong, Yu Zhang, Yuma Yang, Qian Yan, Jifeng Ren, Jie Luo, Yuen Chak Tiu, Xiaona Fang, Beilei Liu, Raymond Hiu Wai Lam, Ka‐On Lam, Anne Wing‐Mui Lee, Xin‐Yuan Guan
Hepatol Commun. 2022 Nov; 6(11): 3194–3211. Published online 2022 Jul 27. doi: 10.1002/hep4.1966
PMCID:
PMC9592791
AbstractArticlePDF–6.8M
12.
LncRNA CARMN Affects Hepatocellular Carcinoma Prognosis by Regulating the miR-192-5p/LOXL2 Axis
Xiaokang Wang, Shulong Wu, Yi Yang, Jingjing Zhao
Oxid Med Cell Longev. 2022; 2022: 9277360. Published online 2022 Oct 8. doi: 10.1155/2022/9277360
PMCID:
PMC9569233
AbstractArticlePDF–4.9M
13.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
14.
A protein interaction landscape of breast cancer
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
Science. Author manuscript; available in PMC 2022 Apr 26.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
PMCID:
PMC9040556
AbstractArticlePDF–2.2M
15.
Increased serum LOXL2 concentration in pelvic inflammatory disease with pelvic adhesion
Chan Xie, Bixin Tang, Kunlun Wu, Qingyi Meng, Fang Wang
BMC Womens Health. 2022; 22: 59. Published online 2022 Mar 4. doi: 10.1186/s12905-022-01640-1
PMCID:
PMC8896148
AbstractArticlePDF–1.0M
16.
Circular RNA circ_0000228 promotes the malignancy of cervical cancer via microRNA-195-5p/ lysyl oxidase-like protein 2 axis
Shimei Liu, Bingqing Li, Ying Li, Huaihua Song
Bioengineered. 2021; 12(1): 4397–4406. Published online 2021 Jul 24. doi: 10.1080/21655979.2021.1954846
PMCID:
PMC8806657
AbstractArticlePDF–1.6M
17.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
18.
Oligomeric States and Hydrodynamic Properties of Lysyl Oxidase-Like 2
Alex A. Meier, Hee-Jung Moon, Ronald Toth, IV, Ewa Folta-Stogniew, Krzysztof Kuczera, C. Russell Middaugh, Minae Mure
Biomolecules. 2021 Dec; 11(12): 1846. Published online 2021 Dec 8. doi: 10.3390/biom11121846
PMCID:
PMC8699698
AbstractArticlePDF–3.8M
19.
An activity‐based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti‐fibrotic therapeutic strategies
Alison Findlay, Craig Turner, Heidi Schilter, Mandar Deodhar, Wenbin Zhou, Lara Perryman, Jonathan Foot, Amna Zahoor, Yimin Yao, Ross Hamilton, Mary Brock, Christina Raso, Jessica Stolp, Marie Galati, Dieter Hamprecht, Brett Charlton, Wolfgang Jarolimek
Clin Transl Med. 2021 Nov; 11(11): e572. Published online 2021 Nov 6. doi: 10.1002/ctm2.572
PMCID:
PMC8571951
ArticlePDF–992K
20.
LOXL2-enriched small extracellular vesicles mediate hypoxia-induced premetastatic niche and indicates poor outcome of head and neck cancer
Guiquan Zhu, Linlin Wang, Wanrong Meng, Shun Lu, Bangrong Cao, Xinhua Liang, Chuanshi He, Yaying Hao, Xueyu Du, Xiaoyi Wang, Longjiang Li, Ling Li
Theranostics. 2021; 11(19): 9198–9216. Published online 2021 Sep 3. doi: 10.7150/thno.62455
PMCID:
PMC8490529
AbstractArticlePDF–3.3M

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