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Items: 1 to 20 of 69

1.
Tyrosine-phosphorylated DNER sensitizes insulin signaling in hepatic gluconeogenesis by inducing proteasomal degradation of TRB3
Junfeng Li, Yan Huang, Xinyu Yang, Yuli Cai, Ye Wang, Wenling Dai, Liu Jiang, Changhua Wang, Zhongyuan Wen
Mol Metab. 2024 May; 83: 101927. Published online 2024 Mar 27. doi: 10.1016/j.molmet.2024.101927
PMCID:
PMC10999696
AbstractArticlePDF–3.9M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Tribbles pseudokinase 3 promotes enterovirus A71 infection via dual mechanisms
Huiqiang Wang, Ke Li, Boming Cui, Haiyan Yan, Shuo Wu, Kun Wang, Ge Yang, Jiandong Jiang, Yuhuan Li
Emerg Microbes Infect. 2024; 13(1): 2307514. Published online 2024 Jan 19. doi: 10.1080/22221751.2024.2307514
PMCID:
PMC10829831
AbstractArticlePDF–4.2M
4.
The pseudokinase TRIB3 controls adipocyte lipid homeostasis and proliferation in vitro and in vivo
Miguel Hernández-Quiles, Laura Martinez Campesino, Imogen Morris, Zabran Ilyas, Steve Reynolds, Nguan Soon Tan, Paula Sobrevals Alcaraz, Edwin C.A. Stigter, Ákos Varga, János Varga, Robert van Es, Harmjan Vos, Heather L. Wilson, Endre Kiss-Toth, Eric Kalkhoven
Mol Metab. 2023 Dec; 78: 101829. Published online 2023 Oct 30. doi: 10.1016/j.molmet.2023.101829
PMCID:
PMC10663684
AbstractArticlePDF–3.5M
5.
Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1
Sumati Gonuguntla, Rohan K. Humphrey, Akshita Gorantla, Ergeng Hao, Ulupi S. Jhala
J Biol Chem. 2023 Aug; 299(8): 104803. Published online 2023 May 11. doi: 10.1016/j.jbc.2023.104803
PMCID:
PMC10432976
AbstractArticlePDF–2.0M
6.
DELE1 is protective for mitochondrial cardiomyopathy
Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu, Chao Chen, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jul 30.
Published in final edited form as: J Mol Cell Cardiol. 2023 Feb; 175: 44–48. Published online 2022 Dec 17. doi: 10.1016/j.yjmcc.2022.12.003
PMCID:
PMC10387237
AbstractArticlePDF–661K
7.
Mitochondrial stress induces an HRI-eIF2α pathway protective for cardiomyopathy
Siting Zhu, Anh Nguyen, Jing Pang, Jun Zhao, Ze’e Chen, Zhengyu Liang, Yusu Gu, Helen Huynh, Yutong Bao, Sharon Lee, Yuval Kluger, Kunfu Ouyang, Sylvia M Evans, Xi Fang
Circulation. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Circulation. 2022 Sep 27; 146(13): 1028–1031. Published online 2022 Sep 26. doi: 10.1161/CIRCULATIONAHA.122.059594
PMCID:
PMC9523491
ArticlePDF–1016K
8.
Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses
Jiani Li, Xuhua Tan, Qihang Sun, Xuri Li, Rongyuan Chen, Lixia Luo
Invest Ophthalmol Vis Sci. 2022 Sep; 63(10): 1. Published online 2022 Sep 1. doi: 10.1167/iovs.63.10.1
PMCID:
PMC9440611
AbstractArticlePDF–10M
9.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
10.
Tribbles Homolog 3 Mediates the Development and Progression of Diabetic Retinopathy
Priyamvada M. Pitale, Irina V. Saltykova, Yvonne Adu-Agyeiwaah, Sergio Li Calzi, Takashi Satoh, Shizuo Akira, Oleg Gorbatyuk, Michael E. Boulton, Machelle T. Pardue, W. Timothy Garvey, Mohammad Athar, Maria B. Grant, Marina S. Gorbatyuk
Diabetes. 2021 Aug; 70(8): 1738–1753. Published online 2021 May 11. doi: 10.2337/db20-1268
PMCID:
PMC8385618
AbstractArticlePDF–4.7M
11.
Tribbles homolog 3-mediated targeting the AKT/mTOR axis in mice with retinal degeneration
Irina V. Saltykova, Asif Elahi, Priyam M. Pitale, Oleg S. Gorbatyuk, Mohammad Athar, Marina S. Gorbatyuk
Cell Death Dis. 2021 Jul; 12(7): 664. Published online 2021 Jul 2. doi: 10.1038/s41419-021-03944-w
PMCID:
PMC8253859
AbstractArticlePDF–4.1M
12.
Obesity-induced TRB3 Negatively Regulates Brown Adipose Tissue Function in Mice
Ha-Won Jeong, Ran Hee Choi, Ho-Jin Koh
Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Apr 2.
Published in final edited form as: Biochem Biophys Res Commun. 2021 Apr 2; 547: 29–35. Published online 2021 Feb 13. doi: 10.1016/j.bbrc.2021.01.103
PMCID:
PMC7982054
AbstractArticlePDF–966K
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation
Xiao-Wei Zhang, Ji-Chao Zhou, Dian Peng, Fang Hua, Ke Li, Jiao-Jiao Yu, Xiao-Xi Lv, Bing Cui, Shan-Shan Liu, Jin-Mei Yu, Feng Wang, Cai-Cai Jin, Zhao-Na Yang, Chen-Xi Zhao, Xue-Ying Hou, Bo Huang, Zhuo-Wei Hu
Autophagy. 2020; 16(5): 782–796. Published online 2019 Jul 9. doi: 10.1080/15548627.2019.1635383
PMCID:
PMC7144866
AbstractArticlePDF–6.5M
15.
Effect of the alteration of Tribbles homologue 3 expression on epithelial-mesenchymal transition of transforming growth factor β1-induced mouse alveolar epithelial cells through the Wnt/β-catenin signaling pathway
Wencheng Yu, Liyun Mi, Feifei Wang
Mol Med Rep. 2020 Feb; 21(2): 615–622. Published online 2019 Dec 5. doi: 10.3892/mmr.2019.10863
PMCID:
PMC6947854
AbstractArticlePDF–752K
16.
Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos
Nadège Poncet, Pamela A Halley, Christopher Lipina, Marek Gierliński, Alwyn Dady, Gail A Singer, Melanie Febrer, Yun‐Bo Shi, Terry P Yamaguchi, Peter M Taylor, Kate G Storey
EMBO Rep. 2020 Jan 7; 21(1): e48469. Published online 2019 Dec 2. doi: 10.15252/embr.201948469
PMCID:
PMC6944906
AbstractArticlePDF–3.5M
17.
TRB3 regulates skeletal muscle mass in food deprivation–induced atrophy
Ran Hee Choi, Abigail McConahay, João G. Silvestre, Anselmo S. Moriscot, James A. Carson, Ho-Jin Koh
FASEB J. 2019 Apr; 33(4): 5654–5666. Published online 2019 Jan 25. doi: 10.1096/fj.201802145RR
PMCID:
PMC6436654
AbstractArticle
18.
Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts
Junlian Gu, Xiaoqing Yan, Xiaozhen Dai, Yuehui Wang, Qian Lin, Jian Xiao, Shanshan Zhou, Jian Zhang, Kai Wang, Jun Zeng, Ying Xin, Michelle T. Barati, Chi Zhang, Yang Bai, Yan Li, Paul N. Epstein, Kupper A. Wintergerst, Xiaokun Li, Yi Tan, Lu Cai
Diabetes. 2018 Mar; 67(3): 507–517. Published online 2017 Oct 27. doi: 10.2337/db17-0219
Correction in:
Diabetes. 2020 Feb; 69(2): 267.
PMCID:
PMC5828458
AbstractArticlePDF–2.0M
19.
The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival
Stefan Norlin, Vishal Parekh, Helena Edlund
Development. 2018 Jan 1; 145(1): dev154468. doi: 10.1242/dev.154468
PMCID:
PMC5825870
AbstractArticle
20.
Developmental nonlinearity drives phenotypic robustness
Rebecca M. Green, Jennifer L. Fish, Nathan M. Young, Francis J. Smith, Benjamin Roberts, Katie Dolan, Irene Choi, Courtney L. Leach, Paul Gordon, James M. Cheverud, Charles C. Roseman, Trevor J. Williams, Ralph S. Marcucio, Benedikt Hallgrímsson
Nat Commun. 2017; 8: 1970. Published online 2017 Dec 6. doi: 10.1038/s41467-017-02037-7
PMCID:
PMC5719035
AbstractArticlePDF–1.4M

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