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Items: 1 to 20 of 402

1.
Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models
Dino Šisl, Pavao Planinić, Sanja Novak, Maša Filipović, Darja Flegar, Alan Šućur, Petra Turčić, Nataša Kovačić, Ivo Kalajzić, Danka Grčević, Tomislav Kelava
Front Pharmacol. 2024; 15: 1440236. Published online 2024 Oct 28. doi: 10.3389/fphar.2024.1440236
PMCID:
PMC11551037
AbstractArticlePDF–4.4M
2.
Robust reprogramming of glia into neurons by inhibition of Notch signaling and nuclear factor I (NFI) factors in adult mammalian retina
Nguyet Le, Trieu-Duc Vu, Isabella Palazzo, Ritvik Pulya, Yehna Kim, Seth Blackshaw, Thanh Hoang
Sci Adv. 2024 Jul 12; 10(28): eadn2091. Published online 2024 Jul 12. doi: 10.1126/sciadv.adn2091
PMCID:
PMC11244444
AbstractArticlePDF–7.9M
3.
Dual Deletion of Keap1 and Rbpjκ Genes in Liver Leads to Hepatomegaly and Hypercholesterolemia
Nobunao Wakabayashi, Yoko Yagishita, Tanvi Joshi, Thomas W. Kensler
Int J Mol Sci. 2024 May; 25(9): 4712. Published online 2024 Apr 26. doi: 10.3390/ijms25094712
PMCID:
PMC11083431
AbstractArticlePDF–5.2M
4.
RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes
Tiantian Kou, Lan Kang, Bin Zhang, Jiaqi Li, Baohong Zhao, Wenwen Zeng, Xiaoyu Hu
eLife. 2024; 12: RP88135. Published online 2024 Feb 26. doi: 10.7554/eLife.88135
PMCID:
PMC10942619
AbstractArticlePDF–3.7M
5.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
6.
DNA methylation–mediated Rbpjk suppression protects against fracture nonunion caused by systemic inflammation
Ding Xiao, Liang Fang, Zhongting Liu, Yonghua He, Jun Ying, Haocheng Qin, Aiwu Lu, Meng Shi, Tiandao Li, Bo Zhang, Jianjun Guan, Cuicui Wang, Yousef Abu-Amer, Jie Shen
J Clin Invest. 2024 Feb 1; 134(3): e168558. Published online 2024 Feb 1. doi: 10.1172/JCI168558
PMCID:
PMC10849763
AbstractArticlePDF–33M
7.
Jagged1 acts as an RBP-J target and feedback suppresses TNF-mediated inflammatory osteoclastogenesis
Courtney Ng, Yongli Qin, Yuhan Xia, Xiaoyu Hu, Baohong Zhao
J Immunol. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: J Immunol. 2023 Nov 1; 211(9): 1340–1347. doi: 10.4049/jimmunol.2300317
PMCID:
PMC10693321
AbstractArticlePDF–2.5M
8.
NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor α
Ernesto Canalis, Jungeun Yu, Vijender Singh, Magda Mocarska, Lauren Schilling
J Biol Chem. 2023 Dec; 299(12): 105372. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105372
PMCID:
PMC10692730
AbstractArticlePDF–2.1M
9.
SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling
Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Junhong Li, Yi Ye, Zhangjian Lai, Zhe Li, Haitao Huang, Jiaxin Li, Jinhuan Li, Mengyu Cheng, Cheng Nian, Na Wu, Zhien Zhou, Yunzhi Xing, Yu Zhao, He Liu, Jiayu Tang, Qinghua Chen, Lixin Hong, Wengang Li, Zhihai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wanjin Hong, Lanfen Chen, Dawang Zhou
J Clin Invest. 2023 Oct 16; 133(20): e168888. Published online 2023 Oct 16. doi: 10.1172/JCI168888
PMCID:
PMC10575737
AbstractArticlePDF–11M
10.
Specific Temporal Requirement of Prox1 Activity During Pancreatic Acinar Cell Development
Angelica S. Martinez-Ramirez, Thomas L. Borders, Leena Paul, Matthew Schipma, Xinkun Wang, Farida Korobova, Christopher V. Wright, Beatriz Sosa-Pineda
Gastro Hep Adv. 2022; 1(5): 807–823. Published online 2022 May 26. doi: 10.1016/j.gastha.2022.05.013
PMCID:
PMC10569262
AbstractArticlePDF–6.7M
11.
Notch pathway mutants do not equivalently perturb mouse embryonic retinal development
Bernadett Bosze, Julissa Suarez-Navarro, Illiana Cajias, Joseph A. Brzezinski IV, Nadean L. Brown
PLoS Genet. 2023 Sep; 19(9): e1010928. Published online 2023 Sep 26. doi: 10.1371/journal.pgen.1010928
PMCID:
PMC10522021
AbstractArticlePDF–5.9M
12.
RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation
Leiling Pan, Medhanie A. Mulaw, Johann Gout, Min Guo, Hina Zarrin, Peggy Schwarz, Bernd Baumann, Thomas Seufferlein, Martin Wagner, Franz Oswald
Cell Mol Gastroenterol Hepatol. 2023; 16(5): 783–807. Published online 2023 Aug 4. doi: 10.1016/j.jcmgh.2023.07.013
PMCID:
PMC10520364
AbstractArticlePDF–12M
13.
Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson’s disease by dominantly regulating resident microglia activation through NF-κB signaling
Shi-Qian Liang, Peng-Hui Li, Yi-Yang Hu, Jun-Long Zhao, Fang-Ze Shao, Fang Kuang, Kai-Xi Ren, Tiao-Xia Wei, Fan Fan, Lei Feng, Hua Han, Hong-Yan Qin
Front Immunol. 2023; 14: 1193081. Published online 2023 Aug 23. doi: 10.3389/fimmu.2023.1193081
PMCID:
PMC10481959
AbstractArticlePDF–4.2M
14.
Rbpj deficiency disrupts vascular remodeling via abnormal Apelin and Cdc42 activity in brain arteriovenous malformation
Subhodip Adhicary, Kayleigh Fanelli, Sera Nakisli, Brittney Ward, Isaac Pearce, Corinne M. Nielsen
Stroke. Author manuscript; available in PMC 2024 Jun 1.
Published in final edited form as: Stroke. 2023 Jun; 54(6): 1593–1605. Published online 2023 Apr 13. doi: 10.1161/STROKEAHA.122.041853
PMCID:
PMC10213117
AbstractArticlePDF–1.4M
15.
Notch Blockade Specifically in Bone Marrow-Derived FSP-1-Positive Cells Ameliorates Renal Fibrosis
Yongdong Wu, Ming Liang, Fengzhang Huang, Owen H. Cheng, Xiaoguang Xiao, Tae Hoon Lee, Luan Truong, Jizhong Cheng
Cells. 2023 Jan; 12(2): 214. Published online 2023 Jan 4. doi: 10.3390/cells12020214
PMCID:
PMC9856686
AbstractArticlePDF–4.8M
16.
A Tamoxifen-inducible Cre Knock-in Mouse for Lens-specific Gene Manipulation
Zongbo Wei, Caili Hao, Jian-Kang Chen, Lin Gan, Xingjun Fan
Exp Eye Res. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Exp Eye Res. 2023 Jan; 226: 109306. Published online 2022 Nov 11. doi: 10.1016/j.exer.2022.109306
PMCID:
PMC9839650
AbstractArticlePDF–1.3M
17.
Endothelial Rbpj deletion normalizes Notch4-induced brain arteriovenous malformation in mice
Corinne M. Nielsen, Xuetao Zhang, Kunal Raygor, Shaoxun Wang, Andrew W. Bollen, Rong A. Wang
J Exp Med. 2023 Feb 6; 220(2): e20211390. Published online 2022 Nov 28. doi: 10.1084/jem.20211390
PMCID:
PMC9700524
AbstractArticlePDF–6.2M
18.
Brain milieu induces early microglial maturation through the BAX-Notch axis
Fangying Zhao, Jiangyong He, Jun Tang, Nianfei Cui, Yanyan Shi, Zhifan Li, Shengnan Liu, Yazhou Wang, Ming Ma, Congjian Zhao, Lingfei Luo, Li Li
Nat Commun. 2022; 13: 6117. Published online 2022 Oct 17. doi: 10.1038/s41467-022-33836-2
PMCID:
PMC9576735
AbstractArticlePDF–8.8M
19.
Perivascular cells support folliculogenesis in the developing ovary
Shu-Yun Li, Bidur Bhandary, Xiaowei Gu, Tony DeFalco
Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2213026119. Published online 2022 Oct 4. doi: 10.1073/pnas.2213026119
PMCID:
PMC9564831
AbstractArticlePDF–4.2M
20.
Notch effector recombination signal binding protein for immunoglobulin kappa J signaling is required for the initiation of endometrial stromal cell decidualization
Genna E Moldovan, Yong Song, Tae Hoon Kim, Ren-Wei Su, Jae-Wook Jeong, Artiom Gruzdev, Thomas E Spencer, Asgerally T Fazleabas
Biol Reprod. 2022 Oct; 107(4): 977–983. Published online 2022 Jul 14. doi: 10.1093/biolre/ioac140
PMCID:
PMC9562121
AbstractArticlePDF–1.0M

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