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Select item 114932001.

TLR2/NF-κB signaling in macrophage/microglia mediated COVID-pain induced by SARS-CoV-2 envelope protein

Huan Cui, Fengrun Sun, Ning Yu, Yan Cao, Xue Wang, Di Zhang, Zhen Chen, Naili Wang, Bo Yuan, Penghao Liu, Wanru Duan, Wenying Qiu, Xiangsha Yin, Chao Ma

iScience. 2024 Oct 18; 27(10): 111027. Published online 2024 Sep 24. doi: 10.1016/j.isci.2024.111027

PMCID:: PMC11493200

Abstract Article PDF–8.5M

Select item 113736162.

Activation of Toll-like receptor 2 promotes mesenchymal stem/stromal cell-mediated immunoregulation and angiostasis through AKR1C1

Jung Hwa Ko, Hyun Ju Lee, Chang Ho Yoon, Yoo Rim Choi, Jin Suk Ryu, Joo Youn Oh

Theranostics. 2024; 14(12): 4713–4729. Published online 2024 Aug 6. doi: 10.7150/thno.100327

PMCID:: PMC11373616

Abstract Article PDF–10M

Select item 112965463.

LGG promotes activation of intestinal ILC3 through TLR2 receptor and inhibits salmonella typhimurium infection in mice

Junhong Wang, Ming Gao, Jiarui Wang, Yan Zeng, Chunfeng Wang, Xin Cao

Virulence. 2024; 15(1): 2384553. Published online 2024 Jul 30. doi: 10.1080/21505594.2024.2384553

PMCID:: PMC11296546

Abstract Article PDF–6.8M

Select item 110783964.

Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease

Kristen L. Lokken-Toyli, Surya D. Aggarwal, Gavyn Chern Wei Bee, Wouter A. A. de Steenhuijsen Piters, Cindy Wu, Kenny Zhi Ming Chen, Cynthia Loomis, Debby Bogaert, Jeffrey N. Weiser

PLoS Pathog. 2024 May; 20(5): e1012111. Published online 2024 May 8. doi: 10.1371/journal.ppat.1012111

PMCID:: PMC11078396

Abstract Article PDF–3.6M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108971706.

DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection

Jian Xu, Li-Yuan Liu, Fei-Jie Zhi, Yin-Juan Song, Zi-Hui Zhang, Bin Li, Fu-Ying Zheng, Peng-Cheng Gao, Su-Zi Zhang, Yu-Yu Zhang, Ying Zhang, Ying Qiu, Bo Jiang, Yong-Qing Li, Chen Peng, Yue-Feng Chu

EMBO Rep. 2024 Feb; 25(2): 770–795. Published online 2024 Jan 5. doi: 10.1038/s44319-023-00047-9

PMCID:: PMC10897170

Abstract Article PDF–7.5M

Select item 107908237.

Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Bibiana Petri da Silveira, Rola Barhoumi, Jocelyne M. Bray, Hannah M. Cole-Pfeiffer, Cory J. Mabry, Robert C. Burghardt, Noah D. Cohen, Angela I. Bordin

Infect Immun. 2024 Jan; 92(1): e00383-23. Published online 2023 Nov 29. doi: 10.1128/iai.00383-23

PMCID:: PMC10790823

Abstract Article PDF–4.6M

Select item 107729378.

TLR2 regulates Moraxella catarrhalis adhesion to and invasion into alveolar epithelial cells and mediates inflammatory responses

Rui Ding, Jinhan Yu, Weixin Ke, Lijun Du, Guixue Cheng, Siqi Hu, Yingchun Xu, Yali Liu

Virulence. 2024; 15(1): 2298548. Published online 2024 Jan 3. doi: 10.1080/21505594.2023.2298548

PMCID:: PMC10772937

Abstract Article PDF–3.6M

Select item 107433679.

Genetic and immune determinants of E. coli liver abscess formation

Karthik Hullahalli, Katherine G. Dailey, Yuko Hasegawa, Encarnacion Torres, Masataka Suzuki, Hailong Zhang, David W. Threadgill, Victor M. Navarro, Matthew K. Waldor

Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51): e2310053120. Published online 2023 Dec 14. doi: 10.1073/pnas.2310053120

PMCID:: PMC10743367

Abstract Article PDF–4.4M

Select item 1071647010.

Aging exacerbates cardiac dysfunction and mortality in sepsis through enhancing TLR2 activity

Yufeng Zhai, Qingzhou Yao, Erlinda The, Lihua Ao, David A. Fullerton, Xianzhong Meng

Front Cardiovasc Med. 2023; 10: 1293866. Published online 2023 Nov 29. doi: 10.3389/fcvm.2023.1293866

PMCID:: PMC10716470

Abstract Article PDF–2.8M

Select item 1071625611.

Commensal bacteria promote type I interferon signaling to maintain immune tolerance in mice

Adriana Vasquez Ayala, Chia-Yun Hsu, Renee E. Oles, Kazuhiko Matsuo, Luke R. Loomis, Ekaterina Buzun, Marvic Carrillo Terrazas, Romana R. Gerner, Hsueh-Han Lu, Sohee Kim, Ziyue Zhang, Jong Hwee Park, Paul Rivaud, Matt Thomson, Li-Fan Lu, Booki Min, Hiutung Chu

J Exp Med. 2024 Jan 1; 221(1): e20230063. Published online 2023 Dec 12. doi: 10.1084/jem.20230063

PMCID:: PMC10716256

Abstract Article PDF–5.2M

Select item 1070283812.

Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals

Yuxin Wang, Tatsuya Morishima, Maiko Sezaki, Ryo Sato, Gaku Nakato, Shinji Fukuda, Kouji Kobiyama, Ken J Ishii, Yuhua Li, Hitoshi Takizawa

EMBO Rep. 2023 Dec; 24(12): e57485. Published online 2023 Oct 23. doi: 10.15252/embr.202357485

PMCID:: PMC10702838

Abstract Article PDF–4.4M

Select item 1068407313.

TLR2 mediates renal apoptosis in neonatal mice subjected experimentally to obstructive nephropathy

Maja Wyczanska, Jana Rohling, Ursula Keller, Marcus R. Benz, Carsten Kirschning, Bärbel Lange-Sperandio

PLoS One. 2023; 18(11): e0294142. Published online 2023 Nov 28. doi: 10.1371/journal.pone.0294142

PMCID:: PMC10684073

Abstract Article PDF–4.2M

Select item 1059381814.

C-type lectin receptor 2d forms homodimers and heterodimers with TLR2 to negatively regulate IRF5-mediated antifungal immunity

Fan Li, Hui Wang, Yan-Qi Li, Yebo Gu, Xin-Ming Jia

Nat Commun. 2023; 14: 6718. Published online 2023 Oct 23. doi: 10.1038/s41467-023-42216-3

PMCID:: PMC10593818

Abstract Article PDF–3.3M

Select item 1054716915.

Akkermansia muciniphila participates in the host protection against helminth-induced cardiac fibrosis via TLR2

Jiaqi Wang, Xiaolei Liu, Ruohang Sun, Hanhai Mao, Mingyuan Liu, Xuemin Jin

PLoS Pathog. 2023 Oct; 19(10): e1011683. Published online 2023 Oct 3. doi: 10.1371/journal.ppat.1011683

PMCID:: PMC10547169

Abstract Article PDF–4.1M

Select item 1050647416.

TLR2 is non-redundant in the population and subpopulation responses to Mycobacterium tuberculosis in macrophages and in vivo

Charul Jani, Sydney L. Solomon, Joshua M. Peters, Stephanie C. Pringle, Amelia E. Hinman, Julie Boucau, Bryan D. Bryson, Amy K. Barczak

mSystems. 2023 Jul-Aug; 8(4): e00052-23. Published online 2023 Jul 13. doi: 10.1128/msystems.00052-23

PMCID:: PMC10506474

Abstract Article PDF–2.5M

Select item 1050381117.

Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer’s disease–related mouse models

Debashis Dutta, Malabendu Jana, Ramesh Kumar Paidi, Moumita Majumder, Sumita Raha, Sridevi Dasarathy, Kalipada Pahan

J Clin Invest. 2023 Sep 15; 133(18): e161987. Published online 2023 Sep 15. doi: 10.1172/JCI161987

PMCID:: PMC10503811

Abstract Article PDF–29M

Select item 1050272618.

Co-infection of mice with SARS-CoV-2 and Mycobacterium tuberculosis limits early viral replication but does not affect mycobacterial loads

Paul J. Baker, Eduardo P. Amaral, Ehydel Castro, Andrea C. Bohrer, Flor Torres-Juárez, Cassandra M. Jordan, Christine E. Nelson, Daniel L. Barber, Reed F. Johnson, Kerry L. Hilligan, Katrin D. Mayer-Barber

Front Immunol. 2023; 14: 1240419. Published online 2023 Sep 1. doi: 10.3389/fimmu.2023.1240419

PMCID:: PMC10502726

Abstract Article PDF–9.6M

Select item 1049147919.

MyD88-dependent Toll-like receptor 2 signaling modulates macrophage activation on lysate-adsorbed Teflon™ AF surfaces in an in vitro biomaterial host response model

Laura A. McKiel, Laurel L. Ballantyne, Gian Luca Negri, Kimberly A. Woodhouse, Lindsay E. Fitzpatrick

Front Immunol. 2023; 14: 1232586. Published online 2023 Aug 24. doi: 10.3389/fimmu.2023.1232586

PMCID:: PMC10491479

Abstract Article PDF–5.6M

Select item 1024039220.

Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway epithelium

Walter V. Velasco, Nasim Khosravi, Susana Castro-Pando, Nelly Torres-Garza, Maria T. Grimaldo, Avantika Krishna, Michael J. Clowers, Misha Umer, Sabah Tariq Amir, Diana Del Bosque, Soudabeh Daliri, Maria Miguelina De La Garza, Marco Ramos-Castaneda, Scott E. Evans, Seyed Javad Moghaddam

Front Immunol. 2023; 14: 1118721. Published online 2023 May 22. doi: 10.3389/fimmu.2023.1118721

PMCID:: PMC10240392

Abstract Article PDF–3.5M

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