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Items: 1 to 20 of 40

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Sphingomyelin synthase–related protein SMSr is a phosphatidylethanolamine phospholipase C that promotes nonalcoholic fatty liver disease
Yeun-po Chiang, Zhiqiang Li, Mulin He, Quiana Jones, Meixia Pan, Xianlin Han, Xian-Cheng Jiang
J Biol Chem. 2023 Sep; 299(9): 105162. Published online 2023 Aug 14. doi: 10.1016/j.jbc.2023.105162
Correction in:
J Biol Chem. 2024 Apr; 300(4): 107204.
PMCID:
PMC10494463
AbstractArticlePDF–3.6M
3.
A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency
Yoritaka Fujii, Makoto Taniguchi, Shingo Nagaya, Yoshibumi Ueda, Chieko Hashizume, Ken Watanabe, Hiroyuki Takeya, Takeo Kosaka, Toshiro Okazaki
Blood Adv. 2021 Oct 26; 5(20): 4265–4277. Published online 2021 Oct 26. doi: 10.1182/bloodadvances.2020002922
PMCID:
PMC8945624
AbstractArticlePDF–1.7M
4.
Sphingomyelin synthases 1 and 2 exhibit phosphatidylcholine phospholipase C activity
Yeun-po Chiang, Zhiqiang Li, Yang Chen, Yu Cao, Xian-Cheng Jiang
J Biol Chem. 2021 Dec; 297(6): 101398. Published online 2021 Nov 10. doi: 10.1016/j.jbc.2021.101398
PMCID:
PMC8648842
AbstractArticlePDF–1.8M
5.
Effect of liver total sphingomyelin synthase deficiency on plasma lipid metabolism
Zhiqiang Li, Yeun-Po Chiang, Mulin He, Ke Zhang, Jiao Zheng, Weihua Wu, Jiajia Cai, Yong Chen, Guangzhi Chen, Yunqin Chen, Jibin Dong, Tilla S. Worgall, Xian-Cheng Jiang
Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2021 May; 1866(5): 158898. Published online 2021 Feb 2. doi: 10.1016/j.bbalip.2021.158898
PMCID:
PMC8022321
AbstractArticlePDF–1.8M
6.
Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry
Patrick Niekamp, Gaelen Guzman, Hans C. Leier, Ali Rashidfarrokhi, Veronica Richina, Fabian Pott, Caroline Barisch, Joost C. M. Holthuis, Fikadu G. Tafesse
mBio. 2021 Jan-Feb; 12(1): e03141-20. Published online 2021 Jan 26. doi: 10.1128/mBio.03141-20
PMCID:
PMC7858061
AbstractArticlePDF–4.5M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation
Goichi Matsumoto, Chieko Hashizume, Ken Watanabe, Makoto Taniguchi, Toshiro Okazaki
Mol Med. 2019; 25: 56. Published online 2019 Dec 17. doi: 10.1186/s10020-019-0123-0
PMCID:
PMC6918654
AbstractArticlePDF–2.2M
9.
Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response
Chenqiong Wang, Bingxia Ming, Xuefen Wu, Tong Wu, Shaozhe Cai, Peng Hu, Jungen Tang, Zheng Tan, Chaohong Liu, Jixin Zhong, Fang Zheng, Lingli Dong
EBioMedicine. 2019 Jul; 45: 578–587. Published online 2019 Jun 28. doi: 10.1016/j.ebiom.2019.06.038
PMCID:
PMC6642282
AbstractArticlePDF–3.5M
10.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
11.
A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis
Matthew R. Jones, Salma Dilai, Arun Lingampally, Cho-Ming Chao, Soula Danopoulos, Gianni Carraro, Regina Mukhametshina, Jochen Wilhelm, Eveline Baumgart-Vogt, Denise Al Alam, Chengshui Chen, Parviz Minoo, Jin San Zhang, Saverio Bellusci
Front Genet. 2018; 9: 746. Published online 2019 Jan 23. doi: 10.3389/fgene.2018.00746
PMCID:
PMC6351499
AbstractArticlePDF–5.6M
12.
2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity
Bin Lou, Qi Liu, Jiahui Hou, Inamul Kabir, Peipei Liu, Tingbo Ding, Jibin Dong, Mingguang Mo, Deyong Ye, Yang Chen, Hai H. Bui, Kenneth Roth, Yu Cao, Xian-Cheng Jiang
J Biol Chem. 2018 Nov 23; 293(47): 18328–18336. Published online 2018 Oct 10. doi: 10.1074/jbc.RA118.005904
Correction in:
J Biol Chem. 2019 May 31; 294(22): 8716.
PMCID:
PMC6254338
AbstractArticlePDF–1.0M
13.
Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development
Shan Li, Amy Teegarden, Emily M. Bauer, Jaewoo Choi, Nadia Messaddeq, David A. Hendrix, Gitali Ganguli-Indra, Mark Leid, Arup K. Indra
Sci Rep. 2017; 7: 13427. Published online 2017 Oct 18. doi: 10.1038/s41598-017-13347-7
PMCID:
PMC5647389
AbstractArticlePDF–5.2M
14.
Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus
Makoto Taniguchi, Takafumi Tasaki, Hideaki Ninomiya, Yoshibumi Ueda, Koh-ichi Kuremoto, Susumu Mitsutake, Yasuyuki Igarashi, Toshiro Okazaki, Tsutomu Takegami
Sci Rep. 2016; 6: 37829. Published online 2016 Nov 28. doi: 10.1038/srep37829
PMCID:
PMC5124946
AbstractArticlePDF–1.6M
15.
Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice
Anke Wittmann, Marcus O. W. Grimm, Harry Scherthan, Marion Horsch, Johannes Beckers, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Steven J. Ford, Neal C. Burton, Daniel Razansky, Dietrich Trümbach, Michaela Aichler, Axel Karl Walch, Julia Calzada-Wack, Frauke Neff, Wolfgang Wurst, Tobias Hartmann, Thomas Floss
PLoS One. 2016; 11(10): e0164298. Published online 2016 Oct 27. doi: 10.1371/journal.pone.0164298
PMCID:
PMC5082796
AbstractArticlePDF–5.6M
16.
Circular RNA of the human sphingomyelin synthase 1 gene: Multiple splice variants, evolutionary conservatism and expression in different tissues
Ivan B Filippenkov, Olga Yu Sudarkina, Svetlana A Limborska, Lyudmila V Dergunova
RNA Biol. 2015 Sep; 12(9): 1030–1042. Published online 2015 Aug 14. doi: 10.1080/15476286.2015.1076611
PMCID:
PMC4615658
AbstractArticlePDF–836K
17.
Sphingomyelin synthase 1 regulates Neuro-2a cell proliferation and cell cycle progression through modulation of p27 expression and Akt signaling
Umadevi V. Wesley, James Hatcher, Robert J. Dempsey
Mol Neurobiol. Author manuscript; available in PMC 2015 Jun 5.
Published in final edited form as: Mol Neurobiol. 2015 Jun; 51(3): 1530–1541. Published online 2014 Aug 2. doi: 10.1007/s12035-014-8829-z
PMCID:
PMC4457447
AbstractArticlePDF–1.8M
18.
All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity
Tingbo Ding, Inamul Kabir, Yue Li, Caixia Lou, Amirfarbod Yazdanyar, Jiachen Xu, Jibin Dong, Hongwen Zhou, Taesik Park, Mohamed Boutjdir, Zhiqiang Li, Xian-Cheng Jiang
J Lipid Res. 2015 Mar; 56(3): 537–545. doi: 10.1194/jlr.M054627
PMCID:
PMC4340302
AbstractArticlePDF–1.2M
19.
Increased Oxidative Stress Impairs Adipose Tissue Function in Sphingomyelin Synthase 1 Null Mice
Masato Yano, Tadashi Yamamoto, Naotaka Nishimura, Tomomi Gotoh, Ken Watanabe, Kazutaka Ikeda, Yohei Garan, Ryo Taguchi, Koichi Node, Toshiro Okazaki, Yuichi Oike
PLoS One. 2013; 8(4): e61380. Published online 2013 Apr 12. doi: 10.1371/journal.pone.0061380
PMCID:
PMC3625169
AbstractArticlePDF–1.2M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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