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Items: 1 to 20 of 101

1.
Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7
Chuang Li, Jiaqi Fu, Shuai Shao, Zhao-Qing Luo
PLoS Pathog. 2024 May; 20(5): e1011783. Published online 2024 May 13. doi: 10.1371/journal.ppat.1011783
PMCID:
PMC11115209
AbstractArticlePDF–4.8M
2.
Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis
Preksha Gaur, Yesheswini Rajendran, Bhagyashree Srivastava, Manasvini Markandey, Vered Fishbain-Yoskovitz, Gayatree Mohapatra, Aamir Suhail, Shikha Chaudhary, Shaifali Tyagi, Subhash Chandra Yadav, Amit Kumar Pandey, Yifat Merbl, Avinash Bajaj, Vineet Ahuja, Chittur Srikanth
eLife. 2024; 12: RP89776. Published online 2024 Apr 9. doi: 10.7554/eLife.89776
PMCID:
PMC11003743
AbstractArticlePDF–11M
3.
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy
Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng
Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2
PMCID:
PMC10864363
AbstractArticlePDF–9.9M
4.
RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension
Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam C. Green, Geoffrey Newcomb, Nuo Sun, Jose A. Ovando-Ricardez, Jeffrey C. Horowitz, Aneel R. Bhagwani, Hu Yang, Tatiana V. Kudryashova, Mauricio Rojas, Ana L. Mora, Pearlly Yan, Rama K. Mallampalli, Elena A. Goncharova, David M. Eckmann, Laszlo Farkas
J Clin Invest. 2024 Feb 1; 134(3): e169441. Published online 2024 Feb 1. doi: 10.1172/JCI169441
PMCID:
PMC10836802
AbstractArticlePDF–3.4M
5.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
6.
Rab7 localized on zymogen granules is involved in maturation but not in autophagy or regulated exocytosis in pancreatic acinar cells
Kenichi Takahashi, Hirosato Mashima, Masanari Sekine, Takeshi Uehara, Takeharu Asano, Ge-Hong Sun-Wada, Yoh Wada, Hirohide Ohnishi
Sci Rep. 2023; 13: 22084. Published online 2023 Dec 12. doi: 10.1038/s41598-023-49520-4
PMCID:
PMC10716180
AbstractArticlePDF–4.3M
7.
Misregulation of mitochondria–lysosome contact dynamics in Charcot–Marie–Tooth Type 2B disease Rab7 mutant sensory peripheral neurons
Yvette C. Wong, Nirupa D. Jayaraj, Tayler B. Belton, George C. Shum, Hannah E. Ball, Dongjun Ren, Abigail L. D. Tadenev, Dimitri Krainc, Robert W. Burgess, Daniela M. Menichella
Proc Natl Acad Sci U S A. 2023 Oct 31; 120(44): e2313010120. Published online 2023 Oct 25. doi: 10.1073/pnas.2313010120
PMCID:
PMC10622892
AbstractArticlePDF–14M
8.
Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired
Wenjing Liang, Shakti Sagar, Rishith Ravindran, Rita H. Najor, Justin M. Quiles, Liguo Chi, Rachel Y. Diao, Benjamin P. Woodall, Leonardo J. Leon, Erika Zumaya, Jason Duran, David M. Cauvi, Antonio De Maio, Eric D. Adler, Åsa B. Gustafsson
Nat Commun. 2023; 14: 5031. Published online 2023 Aug 18. doi: 10.1038/s41467-023-40680-5
PMCID:
PMC10439183
AbstractArticlePDF–7.6M
9.
Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy
Kristin Vöing, Ulf Michgehl, Nils David Mertens, Cara Picciotto, Mee-Ling Maywald, Jonas Goretzko, Sofie Waimann, Kevin Gilhaus, Manuel Rogg, Christoph Schell, Jürgen Klingauf, Yaroslav Tsytsyura, Uwe Hansen, Veerle van Marck, Aimee L. Edinger, Beate Vollenbröker, Ursula Rescher, Daniela Anne Braun, Britta George, Thomas Weide, Hermann Pavenstädt
J Am Soc Nephrol. 2023 Jul; 34(7): 1191–1206. Published online 2023 Apr 5. doi: 10.1681/ASN.0000000000000126
PMCID:
PMC10356157
AbstractArticle
10.
Loss of small GTPase Rab7 activation in prion infection negatively affects a feedback loop regulating neuronal cholesterol metabolism
Pearl Cherry, Li Lu, Su Yeon Shim, Vincent Ebacher, Waqas Tahir, Hermann M. Schatzl, Samia Hannaoui, Sabine Gilch
J Biol Chem. 2023 Feb; 299(2): 102883. Published online 2023 Jan 7. doi: 10.1016/j.jbc.2023.102883
PMCID:
PMC9926124
AbstractArticlePDF–5.7M
11.
PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination
Xinfang Yu, Wei Li, Haidan Liu, Xu Wang, Cristian Coarfa, Chao Cheng, Xinlian Yu, Zhaoyang Zeng, Ya Cao, Ken H. Young, Yong Li
J Clin Invest. 2023 Feb 1; 133(3): e160456. Published online 2023 Feb 1. doi: 10.1172/JCI160456
PMCID:
PMC9888393
AbstractArticlePDF–5.0M
12.
Borcs6 is required for endo-lysosomal degradation during early development
Charlotte J. Bell, Neha Gupta, Kimberly D. Tremblay, Jesse Mager
Mol Reprod Dev. Author manuscript; available in PMC 2023 Aug 1.
Published in final edited form as: Mol Reprod Dev. 2022 Aug; 89(8): 337–350. Published online 2022 Jun 21. doi: 10.1002/mrd.23626
PMCID:
PMC9391301
AbstractArticlePDF–2.8M
13.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
14.
TMED2 binding restricts SMO to the ER and Golgi compartments
Giulio Di Minin, Markus Holzner, Alice Grison, Charles E. Dumeau, Wesley Chan, Asun Monfort, Loydie A. Jerome-Majewska, Henk Roelink, Anton Wutz
PLoS Biol. 2022 Mar; 20(3): e3001596. Published online 2022 Mar 30. doi: 10.1371/journal.pbio.3001596
PMCID:
PMC9000059
AbstractArticlePDF–4.1M
15.
CREG1 promotes lysosomal biogenesis and function
Jie Liu, Yanmei Qi, Joshua Chao, Pranav Sathuvalli, Leonard Y. Lee, Shaohua Li
Autophagy. 2021; 17(12): 4249–4265. Published online 2021 May 8. doi: 10.1080/15548627.2021.1909997
PMCID:
PMC8726608
AbstractArticlePDF–9.2M
16.
Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm
Ge-Hong Sun-Wada, Hiroyuki Tabata, Yoh Wada
Sci Rep. 2021; 11: 19355. Published online 2021 Sep 29. doi: 10.1038/s41598-021-98952-3
PMCID:
PMC8481250
AbstractArticlePDF–3.5M
17.
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH
Hanhai Zeng, Huaijun Chen, Min Li, Jianfeng Zhuang, Yucong Peng, Hang Zhou, Chaoran Xu, Qian Yu, Xiongjie Fu, Shenglong Cao, Jing Cai, Feng Yan, Gao Chen
J Neuroinflammation. 2021; 18: 210. Published online 2021 Sep 16. doi: 10.1186/s12974-021-02270-4
PMCID:
PMC8447596
AbstractArticlePDF–5.1M
18.
ATF3 induces RAB7 to govern autodegradation in paligenosis, a conserved cell plasticity program
Megan D Radyk, Lillian B Spatz, Bianca L Peña, Jeffrey W Brown, Joseph Burclaff, Charles J Cho, Yan Kefalov, Chien‐Cheng Shih, James AJ Fitzpatrick, Jason C Mills
EMBO Rep. 2021 Sep 6; 22(9): e51806. Published online 2021 Jul 26. doi: 10.15252/embr.202051806
PMCID:
PMC8419698
AbstractArticlePDF–4.2M
19.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
20.
Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of INCL
Chinmoy Sarkar, Tamal Sadhukhan, Maria B. Bagh, Abhilash P. Appu, Goutam Chandra, Avisek Mondal, Arjun Saha, Anil B. Mukherjee
J Inherit Metab Dis. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: J Inherit Metab Dis. 2020 Sep; 43(5): 1082–1101. Published online 2020 Apr 27. doi: 10.1002/jimd.12242
PMCID:
PMC8261861
AbstractArticlePDF–2.6M

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