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Select item 112508431.

Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape

Lele Song, Qinglan Li, Lingbo Xia, Arushi Eesha Sahay, Qi Qiu, Yuanyuan Li, Haitao Li, Kotaro Sasaki, Katalin Susztak, Hao Wu, Liling Wan

Nat Commun. 2024; 15: 5937. Published online 2024 Jul 15. doi: 10.1038/s41467-024-50171-w

PMCID:: PMC11250843

Abstract Article PDF–12M

Select item 110765932.

Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster

Alicia Hurtado, Irene Mota-Gómez, Miguel Lao, Francisca M. Real, Johanna Jedamzick, Miguel Burgos, Darío G. Lupiáñez, Rafael Jiménez, Francisco J. Barrionuevo

Nat Commun. 2024; 15: 3809. Published online 2024 May 7. doi: 10.1038/s41467-024-47658-x

PMCID:: PMC11076593

Abstract Article PDF–4.4M

Select item 108971883.

Cep120 is essential for kidney stromal progenitor cell growth and differentiation

Ewa Langner, Tao Cheng, Eirini Kefaloyianni, Charles Gluck, Baolin Wang, Moe R Mahjoub

EMBO Rep. 2024 Jan; 25(1): 428–454. Published online 2023 Dec 20. doi: 10.1038/s44319-023-00019-z

PMCID:: PMC10897188

Abstract Article PDF–7.2M

Select item 108669854.

Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification

Yong-Wei Xiong, Hua-Long Zhu, Jin Zhang, Hao Geng, Lu-Lu Tan, Xin-Mei Zheng, Hao Li, Long-Long Fan, Xin-Run Wang, Xu-Dong Zhang, Kai-Wen Wang, Wei Chang, Yu-Feng Zhang, Zhi Yuan, Zong-Liu Duan, Yun-Xia Cao, Xiao-Jin He, De-Xiang Xu, Hua Wang

Nat Commun. 2024; 15: 1353. Published online 2024 Feb 14. doi: 10.1038/s41467-024-45675-4

PMCID:: PMC10866985

Abstract Article PDF–4.2M

Select item 107535875.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 106901096.

Netrin 1 directs vascular patterning and maturity in the developing kidney

Samuel E. Honeycutt, Pierre-Emmanuel Y. N'Guetta, Deanna M. Hardesty, Yubin Xiong, Shamus L. Cooper, Matthew J. Stevenson, Lori L. O'Brien

Development. 2023 Nov 15; 150(22): dev201886. Published online 2023 Nov 24. doi: 10.1242/dev.201886

PMCID:: PMC10690109

Abstract Article

Select item 106564277.

GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter

Jennifer Kurz, Anna-Carina Weiss, Timo H.-W. Lüdtke, Lena Deuper, Mark-Oliver Trowe, Hauke Thiesler, Herbert Hildebrandt, Joerg Heineke, Stephen A. Duncan, Andreas Kispert

Development. 2022 Aug 1; 149(15): dev200522. Published online 2022 Jul 29. doi: 10.1242/dev.200522

PMCID:: PMC10656427

Abstract Article

Select item 105649988.

Memory discrimination is promoted by the expression of the transcription repressor WT1 in the dentate gyrus

Leonardo Munari, Vishwendra Patel, Nicholas Johnson, Chiara Mariottini, Som Prabha, Robert D. Blitzer, Ravi Iyengar

Front Behav Neurosci. 2023; 17: 1130840. Published online 2023 Sep 27. doi: 10.3389/fnbeh.2023.1130840

PMCID:: PMC10564998

Abstract Article PDF–4.2M

Select item 105234809.

HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma

Joelle S. Suarez, Flavia Novelli, Keisuke Goto, Michiko Ehara, Mika Steele, Jin-Hee Kim, Alicia A. Zolondick, Jiaming Xue, Ronghui Xu, Mai Saito, Sandra Pastorino, Michael Minaai, Yasutaka Takanishi, Mitsuru Emi, Ian Pagano, Andrew Wakeham, Thorsten Berger, Harvey I. Pass, Giovanni Gaudino, Tak W. Mak, Michele Carbone, Haining Yang

Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2307999120. Published online 2023 Sep 20. doi: 10.1073/pnas.2307999120

PMCID:: PMC10523480

Abstract Article PDF–4.1M

Select item 1050641310.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 1049282811.

Cell diversity and plasticity during atrioventricular heart valve EMTs

Jeremy Lotto, Rebecca Cullum, Sibyl Drissler, Martin Arostegui, Victoria C. Garside, Bettina M. Fuglerud, Makenna Clement-Ranney, Avinash Thakur, T. Michael Underhill, Pamela A. Hoodless

Nat Commun. 2023; 14: 5567. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41279-6

PMCID:: PMC10492828

Abstract Article PDF–4.2M

Select item 1041187012.

Innervation of the developing kidney in vivo and in vitro

Julia Tarnick, Mona Elhendawi, Ian Holland, Ziyuan Chang, Jamie A. Davies

Biol Open. 2023 Aug 15; 12(8): bio060001. Published online 2023 Jul 31. doi: 10.1242/bio.060001

PMCID:: PMC10411870

Abstract Article PDF–5.7M

Select item 1037700313.

Targeted Disruption of the MORG1 Gene in Mice Causes Embryonic Resorption in Early Phase of Development

Sophie Wulf, Luisa Mizko, Karl-Heinz Herrmann, Marta Sánchez-Carbonell, Anja Urbach, Cornelius Lemke, Alexander Berndt, Ivonne Loeffler, Gunter Wolf

Biomolecules. 2023 Jul; 13(7): 1037. Published online 2023 Jun 24. doi: 10.3390/biom13071037

PMCID:: PMC10377003

Abstract Article PDF–2.0M

Select item 1012146814.

Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia

Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon

iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500

PMCID:: PMC10121468

Abstract Article PDF–12M

Select item 1011291415.

Endothelial deletion of Wt1 disrupts coronary angiogenesis and myocardium development

Marina Ramiro-Pareta, Claudia Müller-Sánchez, Rosa Portella-Fortuny, Carolina Soler-Botija, Alejo Torres-Cano, Anna Esteve-Codina, Antoni Bayés-Genís, Manuel Reina, Francesc X. Soriano, Eloi Montanez, Ofelia M. Martínez-Estrada

Development. 2023 Mar 15; 150(6): dev201147. Published online 2023 Mar 27. doi: 10.1242/dev.201147