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Items: 1 to 20 of 98

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Retinal Dysfunction in a Mouse Model of HCN1 Genetic Epilepsy
Da Zhao, Paulo Pinares-Garcia, Chaseley E. McKenzie, Lauren E. Bleakley, Ian C. Forster, Vickie H.Y. Wong, Christine T.O. Nguyen, Ingrid E. Scheffer, Christopher A. Reid, Bang V. Bui
J Neurosci. 2023 Mar 22; 43(12): 2199–2209. doi: 10.1523/JNEUROSCI.1615-22.2022
PMCID:
PMC10039744
AbstractArticlePDF–2.6M
4.
Glucocorticoid-glucocorticoid receptor-HCN1 channels reduce neuronal excitability in dorsal hippocampal CA1 neurons
Jiwon Kim, Yun Lei, Xin-Yun Lu, Chung Sub Kim
Mol Psychiatry. 2022; 27(10): 4035–4049. Published online 2022 Jul 15. doi: 10.1038/s41380-022-01682-9
PMCID:
PMC9718682
AbstractArticlePDF–10M
5.
Seizures, behavioral deficits, and adverse drug responses in two new genetic mouse models of HCN1 epileptic encephalopathy
Andrea Merseburg, Jacquelin Kasemir, Eric W Buss, Felix Leroy, Tobias Bock, Alessandro Porro, Anastasia Barnett, Simon E Tröder, Birgit Engeland, Malte Stockebrand, Anna Moroni, Steven A Siegelbaum, Dirk Isbrandt, Bina Santoro
eLife. 2022; 11: e70826. Published online 2022 Aug 16. doi: 10.7554/eLife.70826
PMCID:
PMC9481245
AbstractArticlePDF–17M
6.
Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions
Miguel Ramirez, Yuliya Badayeva, Joanna Yeung, Joshua Wu, Ayasha Abdalla-Wyse, Erin Yang, FANTOM 5 Consortium, Brett Trost, Stephen W Scherer, Daniel Goldowitz
eLife. 2022; 11: e74207. Published online 2022 Aug 9. doi: 10.7554/eLife.74207
PMCID:
PMC9398453
AbstractArticlePDF–5.5M
7.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
8.
Cone-Driven Retinal Responses Are Shaped by Rod But Not Cone HCN1
Colten K. Lankford, Yumiko Umino, Deepak Poria, Vladimir Kefalov, Eduardo Solessio, Sheila A. Baker
J Neurosci. 2022 May 25; 42(21): 4231–4249. doi: 10.1523/JNEUROSCI.2271-21.2022
PMCID:
PMC9145265
AbstractArticlePDF–6.9M
9.
Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice
Anna Katharina Schlusche, Sabine Ulrike Vay, Niklas Kleinenkuhnen, Steffi Sandke, Rafael Campos-Martín, Marta Florio, Wieland Huttner, Achim Tresch, Jochen Roeper, Maria Adele Rueger, Igor Jakovcevski, Malte Stockebrand, Dirk Isbrandt
Proc Natl Acad Sci U S A. 2021 Aug 31; 118(35): e2009393118. Published online 2021 Aug 24. doi: 10.1073/pnas.2009393118
PMCID:
PMC8536352
AbstractArticlePDF–2.2M
10.
Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy
Lauren E Bleakley, Chaseley E McKenzie, Ming S Soh, Ian C Forster, Paulo Pinares-Garcia, Alicia Sedo, Anirudh Kathirvel, Leonid Churilov, Nikola Jancovski, Snezana Maljevic, Samuel F Berkovic, Ingrid E Scheffer, Steven Petrou, Bina Santoro, Christopher A Reid
Brain. 2021 Jul; 144(7): 2060–2073. Published online 2021 Apr 1. doi: 10.1093/brain/awab145
PMCID:
PMC8370418
AbstractArticlePDF–1.7M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age‐dependent changes
Maria Luque, Anneliese Schrott‐Fischer, Jozsef Dudas, Elisabeth Pechriggl, Erich Brenner, Helge Rask‐Andersen, Wei Liu, Rudolf Glueckert
J Neurosci Res. 2021 Feb; 99(2): 699–728. Published online 2020 Nov 12. doi: 10.1002/jnr.24754
PMCID:
PMC7839784
AbstractArticlePDF–5.2M
13.
Deep posteromedial cortical rhythm in dissociation
Sam Vesuna, Isaac V. Kauvar, Ethan Richman, Felicity Gore, Tomiko Oskotsky, Clara Sava-Segal, Liqun Luo, Robert C. Malenka, Jaimie M. Henderson, Paul Nuyujukian, Josef Parvizi, Karl Deisseroth
Nature. Author manuscript; available in PMC 2020 Oct 13.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 87–94. Published online 2020 Sep 16. doi: 10.1038/s41586-020-2731-9
PMCID:
PMC7553818
AbstractArticlePDF–6.6M
14.
HCN2 and HCN1 Channels Govern the Regularity of Autonomous Pacemaking and Synaptic Resetting in Globus Pallidus Neurons
C. Savio Chan, Ryuichi Shigemoto, Jeff N. Mercer, D. James Surmeier
J Neurosci. 2004 Nov 3; 24(44): 9921–9932. doi: 10.1523/JNEUROSCI.2162-04.2004
PMCID:
PMC6730257
AbstractArticlePDF–679K
15.
Regulation of HCN Channel Surface Expression by a Novel C-Terminal Protein-Protein Interaction
Bina Santoro, Brian J. Wainger, Steven A. Siegelbaum
J Neurosci. 2004 Nov 24; 24(47): 10750–10762. doi: 10.1523/JNEUROSCI.3300-04.2004
PMCID:
PMC6730122
AbstractArticlePDF–747K
16.
Dendritic Excitability of Mouse Frontal Cortex Pyramidal Neurons Is Shaped by the Interaction among HCN, Kir2, and Kleak Channels
Michelle Day, David B. Carr, Sasha Ulrich, Ema Ilijic, Tatiana Tkatch, D. James Surmeier
J Neurosci. 2005 Sep 21; 25(38): 8776–8787. doi: 10.1523/JNEUROSCI.2650-05.2005
PMCID:
PMC6725503
AbstractArticlePDF–18M
17.
Targeting peripheral somatosensory neurons to improve tactile-related phenotypes in ASD models
Lauren L. Orefice, Jacqueline R. Mosko, Danielle T. Morency, Michael F. Wells, Aniqa Tasnim, Shawn M. Mozeika, Mengchen Ye, Anda M. Chirila, Alan J. Emanuel, Genelle Rankin, Ryann M. Fame, Maria K. Lehtinen, Guoping Feng, David D. Ginty
Cell. Author manuscript; available in PMC 2020 Aug 8.
Published in final edited form as: Cell. 2019 Aug 8; 178(4): 867–886.e24. doi: 10.1016/j.cell.2019.07.024
PMCID:
PMC6704376
AbstractArticlePDF–3.2M
18.
HCN1 Channels Control Resting and Active Integrative Properties of Stellate Cells from Layer II of the Entorhinal Cortex
Matthew F. Nolan, Joshua T. Dudman, Paul D. Dodson, Bina Santoro
J Neurosci. 2007 Nov 14; 27(46): 12440–12451. doi: 10.1523/JNEUROSCI.2358-07.2007
PMCID:
PMC6673323
AbstractArticlePDF–709K
19.
Estrous Cycle Plasticity in the Hyperpolarization-Activated Current Ih Is Mediated by Circulating 17β-Estradiol in Preoptic Area Kisspeptin Neurons
Richard Piet, Ulrich Boehm, Allan E. Herbison
J Neurosci. 2013 Jun 26; 33(26): 10828–10839. doi: 10.1523/JNEUROSCI.1021-13.2013
PMCID:
PMC6618493
AbstractArticlePDF–3.7M
20.
Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis
Yossi Buskila, Orsolya Kékesi, Alba Bellot-Saez, Winston Seah, Tracey Berg, Michael Trpceski, Justin J. Yerbury, Lezanne Ooi
Cell Death Dis. 2019 Apr; 10(4): 310. Published online 2019 Apr 5. doi: 10.1038/s41419-019-1538-9
PMCID:
PMC6450866
AbstractArticlePDF–1.5M

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