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Items: 1 to 20 of 80

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Deregulated protein homeostasis constrains fetal hematopoietic stem cell pool expansion in Fanconi anemia
Narasaiah Kovuru, Makiko Mochizuki-Kashio, Theresa Menna, Greer Jeffrey, Yuning Hong, Young me Yoon, Zhe Zhang, Peter Kurre
Nat Commun. 2024; 15: 1852. Published online 2024 Feb 29. doi: 10.1038/s41467-024-46159-1
PMCID:
PMC10904799
AbstractArticlePDF–2.5M
3.
Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development
Nazareno Bona, Gerry P. Crossan
Nat Struct Mol Biol. 2023; 30(10): 1434–1445. Published online 2023 Aug 14. doi: 10.1038/s41594-023-01067-8
PMCID:
PMC10584689
AbstractArticlePDF–9.2M
4.
FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells
Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin, Zi-Jiang Chen
BMC Biol. 2023; 21: 174. Published online 2023 Aug 15. doi: 10.1186/s12915-023-01676-1
PMCID:
PMC10426154
AbstractArticlePDF–6.6M
5.
Fance deficiency inhibits primordial germ cell proliferation associated with transcription–replication conflicts accumulate and DNA repair defects
Zhixian Zhou, Huan Yin, Suye Suye, Zhen Ren, Lei Yan, Liye Shi, Chun Fu
J Ovarian Res. 2023; 16: 160. Published online 2023 Aug 10. doi: 10.1186/s13048-023-01252-9
PMCID:
PMC10416540
AbstractArticlePDF–15M
6.
The Validation of a Precursor Lesion of Epithelial Ovarian Cancer in Fancd2-KO Mice
Sarah Sczelecki, Janet L. Pitman
Cancers (Basel) 2023 May; 15(9): 2595. Published online 2023 May 3. doi: 10.3390/cancers15092595
PMCID:
PMC10177028
AbstractArticlePDF–2.4M
7.
DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development
Simin Zhao, Chengzi Huang, Yajuan Yang, Weiwei Xu, Yongze Yu, Canxin Wen, Lili Cao, Fei Gao, Yingying Qin, Zi-Jiang Chen, Ting Guo, Shidou Zhao
J Biol Chem. 2023 Mar; 299(3): 102905. Published online 2023 Jan 13. doi: 10.1016/j.jbc.2023.102905
PMCID:
PMC9971320
AbstractArticlePDF–4.2M
8.
TGFβ pathway is required for viable gestation of Fanconi anemia embryos
Alfredo Rodríguez, Michael Epperly, Jessica Filiatrault, Martha Velázquez, Chunyu Yang, Kelsey McQueen, Larissa A. Sambel, Huy Nguyen, Divya Ramalingam Iyer, Ulises Juárez, Cecilia Ayala-Zambrano, David B. Martignetti, Sara Frías, Renee Fisher, Kalindi Parmar, Joel S. Greenberger, Alan D. D’Andrea
PLoS Genet. 2022 Nov; 18(11): e1010459. Published online 2022 Nov 28. doi: 10.1371/journal.pgen.1010459
PMCID:
PMC9731498
AbstractArticlePDF–3.4M
9.
Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability
Yajuan Yang, Weiwei Xu, Fei Gao, Canxin Wen, Simin Zhao, Yongze Yu, Wenlin Jiao, Xin Mi, Yingying Qin, Zi-Jiang Chen, Shidou Zhao
Proc Natl Acad Sci U S A. 2022 Aug 23; 119(34): e2203208119. Published online 2022 Aug 15. doi: 10.1073/pnas.2203208119
PMCID:
PMC9407672
AbstractArticlePDF–2.8M
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex
Pauline Antonie Ulmke, M. Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann, Huu Phuc Nguyen, Andre Fischer, Gregor Eichele, Jochen F. Staiger, Tran Tuoc
Stem Cell Reports. 2021 Apr 13; 16(4): 968–984. Published online 2021 Apr 1. doi: 10.1016/j.stemcr.2021.03.008
PMCID:
PMC8072132
AbstractArticlePDF–8.1M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin
Sonya Ruiz-Torres, Marion G. Brusadelli, David P. Witte, Kathryn A. Wikenheiser-Brokamp, Sharon Sauter, Adam S. Nelson, Mathieu Sertorio, Timothy M. Chlon, Adam Lane, Parinda A. Mehta, Kasiani C. Myers, Mary C. Bedard, Bidisha Pal, Dorothy M. Supp, Paul F. Lambert, Kakajan Komurov, Melinda Butsch Kovacic, Stella M. Davies, Susanne I. Wells
Cell Stem Cell. Author manuscript; available in PMC 2022 Mar 4.
Published in final edited form as: Cell Stem Cell. 2021 Mar 4; 28(3): 424–435.e6. Published online 2020 Nov 23. doi: 10.1016/j.stem.2020.10.012
PMCID:
PMC7935766
AbstractArticlePDF–1.3M
14.
FANCD2 and HES1 suppress inflammation-induced PPARɣ to prevent haematopoietic stem cell exhaustion
Limei Wu, Xue Li, Qiqi Lin, Fabliha Chowdhury, Md H. Mazumder, Wei Du
Br J Haematol. Author manuscript; available in PMC 2021 Feb 3.
Published in final edited form as: Br J Haematol. 2021 Feb; 192(3): 652–663. Published online 2020 Nov 22. doi: 10.1111/bjh.17230
PMCID:
PMC7856217
AbstractArticlePDF–1.6M
15.
SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis
Alisa Atkins, Michelle J Xu, Maggie Li, Nathaniel P Rogers, Marina V Pryzhkova, Philip W Jordan
eLife. 2020; 9: e61171. Published online 2020 Nov 17. doi: 10.7554/eLife.61171
PMCID:
PMC7723410
AbstractArticlePDF–3.2M
16.
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner
Meng Wang, Laura T.L. Brandt, Xiaonan Wang, Holly Russell, Emily Mitchell, Ashley N. Kamimae-Lanning, Jill M. Brown, Felix A. Dingler, Juan I. Garaycoechea, Tomoya Isobe, Sarah J. Kinston, Muxin Gu, George S. Vassiliou, Nicola K. Wilson, Berthold Göttgens, Ketan J. Patel
Mol Cell. Author manuscript; available in PMC 2023 Aug 4.
Published in final edited form as: Mol Cell. 2023 Jul 20; 83(14): 2417–2433.e7. Published online 2023 Jun 21. doi: 10.1016/j.molcel.2023.05.035
PMCID:
PMC7614878
AbstractArticlePDF–7.0M
17.
Fancd2 is required for the repression of germline transposable elements
Yan Nie, Andrew F. Wilson, Tony DeFalco, Amom Ruhikanta Meetei, Satoshi H Namekawa, Qishen Pang
Reproduction. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Reproduction. 2020 Jun; 159(6): 659–668. doi: 10.1530/REP-19-0436
PMCID:
PMC7193181
AbstractArticlePDF–1.4M
18.
Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation
Srinivas Chatla, Wei Du, Andrew F. Wilson, Amom Ruhikanta Meetei, Qishen Pang
Stem Cell Res. Author manuscript; available in PMC 2019 Dec 12.
Published in final edited form as: Stem Cell Res. 2019 Oct; 40: 101550. Published online 2019 Aug 23. doi: 10.1016/j.scr.2019.101550
PMCID:
PMC6907690
AbstractArticlePDF–1.2M
19.
Sex-specific hepatic lipid and bile acid metabolism alterations in Fancd2-deficient mice following dietary challenge
Elizabeth S. Moore, Erin K. Daugherity, David I. Karambizi, Bethany P. Cummings, Erica Behling-Kelly, Deanna M. W. Schaefer, Teresa L. Southard, Joseph W. McFadden, Robert S. Weiss
J Biol Chem. 2019 Oct 25; 294(43): 15623–15637. Published online 2019 Aug 21. doi: 10.1074/jbc.RA118.005729
PMCID:
PMC6816084
AbstractArticlePDF–3.7M
20.
A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2
Emilie L Dubois, Laure Guitton-Sert, Mariline Béliveau, Kalindi Parmar, Jalila Chagraoui, Julien Vignard, Joris Pauty, Marie-Christine Caron, Yan Coulombe, Rémi Buisson, Karine Jacquet, Clémence Gamblin, Yuandi Gao, Patrick Laprise, Michel Lebel, Guy Sauvageau, Alan D. d’Andrea, Jean-Yves Masson
Nucleic Acids Res. 2019 Aug 22; 47(14): 7532–7547. Published online 2019 Jun 20. doi: 10.1093/nar/gkz514
PMCID:
PMC6698648
AbstractArticlePDF–6.0M

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