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Items: 1 to 20 of 32

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
Ablation of SMUG1 Reduces Cell Viability and Increases UVC-Mediated Apoptosis in Hepatocarcinoma HepG2 Cells
Mi-Jin An, Geun-Seup Shin, Hyun-Min Lee, Jung-Woong Kim
Genes (Basel) 2021 Feb; 12(2): 201. Published online 2021 Jan 30. doi: 10.3390/genes12020201
PMCID:
PMC7911780
AbstractArticlePDF–5.4M
3.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
4.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
5.
The Role of Active-Site Residues Phe98, His239, and Arg243 in DNA Binding and in the Catalysis of Human Uracil–DNA Glycosylase SMUG1
Danila A. Iakovlev, Irina V. Alekseeva, Yury N. Vorobjev, Nikita A. Kuznetsov, Olga S. Fedorova
Molecules. 2019 Sep; 24(17): 3133. Published online 2019 Aug 28. doi: 10.3390/molecules24173133
PMCID:
PMC6749576
AbstractArticlePDF–3.1M
6.
Excision of uracil from DNA by hSMUG1 includes strand incision and processing
Marina Alexeeva, Marivi N Moen, Kristin Grøsvik, Almaz N Tesfahun, Xiang Ming Xu, Izaskun Muruzábal-Lecumberri, Kristine M Olsen, Anette Rasmussen, Peter Ruoff, Finn Kirpekar, Arne Klungland, Svein Bjelland
Nucleic Acids Res. 2019 Jan 25; 47(2): 779–793. Published online 2018 Nov 28. doi: 10.1093/nar/gky1184
PMCID:
PMC6344882
AbstractArticlePDF–3.1M
7.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
8.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
9.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M
10.
Widespread expansion of protein interaction capabilities by alternative splicing
Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal
Cell. Author manuscript; available in PMC 2017 Feb 11.
Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029
PMCID:
PMC4882190
AbstractArticlePDF–1.9M
11.
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect
Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva
RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030
PMCID:
PMC4841607
AbstractArticlePDF–1.6M
12.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
13.
Single nucleotide polymorphisms in uracil-processing genes, intake of one-carbon nutrients and breast cancer risk
Catalin Marian, Meng Hua Tao, Joel B Mason, David S Goerlitz, Jing Nie, Aurelie Chanson, Jo L Freudenheim, Peter G Shields
Eur J Clin Nutr. Author manuscript; available in PMC 2014 Jan 27.
Published in final edited form as: Eur J Clin Nutr. 2011 Jun; 65(6): 683–689. Published online 2011 Mar 23. doi: 10.1038/ejcn.2011.29
PMCID:
PMC3902360
AbstractArticlePDF–94K
14.
Variation Within DNA Repair Pathway Genes and Risk of Multiple Sclerosis
Farren B. S. Briggs, Benjamin A. Goldstein, Jacob L. McCauley, Rebecca L. Zuvich, Philip L. De Jager, John D. Rioux, Adrian J. Ivinson, Alastair Compston, David A. Hafler, Stephen L. Hauser, Jorge R. Oksenberg, Stephen J. Sawcer, Margaret A. Pericak-Vance, Jonathan L. Haines, Lisa F. Barcellos, for the International Multiple Sclerosis Genetics Consortium
Am J Epidemiol. 2010 Jul 15; 172(2): 217–224. Published online 2010 Jun 3. doi: 10.1093/aje/kwq086
PMCID:
PMC3658128
AbstractArticlePDF–129K
15.
SMUG1 BUT NOT UNG DNA GLYCOSYLASE CONTRIBUTES TO THE CELLULAR RESPONSE TO RECOVERY FROM 5-FLUOROURACIL INDUCED REPLICATION STRESS
Pratik Nagaria, David Svilar, Ashley R. Brown, Xiao-hong Wang, Robert W. Sobol, Michael D. Wyatt
Mutat Res. Author manuscript; available in PMC 2014 Mar 1.
Published in final edited form as: Mutat Res. 2013 Mar-Apr; 0: 26–32. Published online 2012 Dec 17. doi: 10.1016/j.mrfmmm.2012.12.001
PMCID:
PMC3616158
AbstractArticlePDF–981K
16.
A Census of Human Soluble Protein Complexes
Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili
Cell. Author manuscript; available in PMC 2013 Aug 31.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011
PMCID:
PMC3477804
AbstractArticlePDF–7.7M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity: SPECIES DIFFERENCES BETWEEN MAN AND MOUSE
Berit Doseth, Torkild Visnes, Anders Wallenius, Ida Ericsson, Antonio Sarno, Henrik Sahlin Pettersen, Arnar Flatberg, Tara Catterall, Geir Slupphaug, Hans E. Krokan, Bodil Kavli
J Biol Chem. 2011 May 13; 286(19): 16669–16680. Published online 2011 Mar 23. doi: 10.1074/jbc.M111.230052
PMCID:
PMC3089509
AbstractArticlePDF–1.3M
19.
Polymorphisms in the Base Excision Repair Pathway and Graft-versus-Host Disease
Mukta Arora, Bruce Lindgren, Saonli Basu, Sriharsha Nagaraj, Myron Gross, Daniel Weisdorf, Bharat Thyagarajan
Leukemia. Author manuscript; available in PMC 2011 Feb 1.
Published in final edited form as: Leukemia. 2010 Aug; 24(8): 1470–1475. Published online 2010 Jun 24. doi: 10.1038/leu.2010.139
PMCID:
PMC2921004
AbstractArticlePDF–415K
20.
Association Between Genetic Variants in the Base Excision Repair Pathway and Outcomes After Hematopoietic Cell Transplants
Bharat Thyagarajan, Bruce Lindgren, Saonli Basu, Sriharsha Nagaraj, Myron D. Gross, Daniel J. Weisdorf, Mukta Arora
Biol Blood Marrow Transplant. Author manuscript; available in PMC 2011 Aug 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2010 Aug; 16(8): 1084–1089. Published online 2010 Mar 11. doi: 10.1016/j.bbmt.2010.03.001
PMCID:
PMC2905878
AbstractArticlePDF–222K

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