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Items: 1 to 20 of 221

1.
PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin
Ritwik Datta, Dibyanti Mukherjee, Michael J. Podolsky, Christopher D. Yang, Diana L. Alba, Sukhmani Singh, Thomas D. Arnold, Suneil Koliwad, Carlos O. Lizama, Kamran Atabai
J Biol Chem. 2024 Feb; 300(2): 105631. Published online 2024 Jan 8. doi: 10.1016/j.jbc.2024.105631
PMCID:
PMC10850974
AbstractArticlePDF–2.9M
2.
High-resolution double vision of the allosteric phosphatase PTP1B
Shivani Sharma, Tamar Skaist Mehlman, Reddy Sudheer Sagabala, Benoit Boivin, Daniel A. Keedy
Acta Crystallogr F Struct Biol Commun. 2024 Jan 1; 80(Pt 1): 1–12. Published online 2024 Jan 1. doi: 10.1107/S2053230X23010749
PMCID:
PMC10833341
AbstractArticlePDF–2.8M
3.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
4.
ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis
Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge
Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335
PMCID:
PMC10627786
AbstractArticlePDF–5.2M
5.
A Conserved Local Structural Motif Controls the Kinetics of PTP1B Catalysis
Christine Y. Yeh, Jesus A. Izaguirre, Jack B. Greisman, Lindsay Willmore, Paul Maragakis, David E. Shaw
J Chem Inf Model. 2023 Jul 10; 63(13): 4115–4124. Published online 2023 Jun 28. doi: 10.1021/acs.jcim.3c00286
PMCID:
PMC10336961
AbstractArticlePDF–5.9M
6.
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell
J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468
PMCID:
PMC10323252
AbstractArticle
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li
Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x
PMCID:
PMC9950447
AbstractArticlePDF–8.4M
9.
Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis
Sheela Nagarkoti, Young-Mee Kim, Dipankar Ash, Archita Das, Eric Vitriol, Tracy-Ann Read, Seock-Won Youn, Varadarajan Sudhahar, Malgorzata McMenamin, Yali Hou, Harriet Boatwright, Ruth Caldwell, David W. Essex, Jaehyung Cho, Tohru Fukai, Masuko Ushio-Fukai
Angiogenesis. Author manuscript; available in PMC 2023 Feb 11.
Published in final edited form as: Angiogenesis. 2023 Feb; 26(1): 77–96. Published online 2022 Aug 19. doi: 10.1007/s10456-022-09852-7
PMCID:
PMC9918675
AbstractArticlePDF–1.7M
10.
PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension
Md Khadem Ali, Xuefei Tian, Lan Zhao, Katharina Schimmel, Christopher J. Rhodes, Martin R. Wilkins, Mark R. Nicolls, Edda F. Spiekerkoetter
Cells. 2023 Jan; 12(2): 316. Published online 2023 Jan 14. doi: 10.3390/cells12020316
PMCID:
PMC9857213
AbstractArticlePDF–2.3M
11.
ETS proto-oncogene 1 modulates PTP1B expression to participate in high glucose-mediated endothelial inflammation: Ets1 modulates PTP1B expression to participate in inflammation
Lili Jiang, Jincai Liang, Tianhai Wang, Fufen Meng, Wenming Duan
Acta Biochim Biophys Sin (Shanghai) 2022 Apr; 54(4): 565–573. Published online 2022 Mar 2. doi: 10.3724/abbs.2022021
PMCID:
PMC9827757
AbstractArticlePDF–9.9M
12.
Targeting the PTP1B‐Bcr‐Abl1 interaction for the degradation of T315I mutant Bcr‐Abl1 in chronic myeloid leukemia
Ahmed Elgehama, Yixuan Wang, Ying Yu, Lin Zhou, Zhixiu Chen, Liwei Wang, Lijun Sun, Jian Gao, Biao Yu, Yan Shen, Qiang Xu
Cancer Sci. 2023 Jan; 114(1): 247–258. Published online 2022 Sep 26. doi: 10.1111/cas.15580
PMCID:
PMC9807508
AbstractArticlePDF–4.3M
13.
The role of PTP1B (PTPN1) in the prognosis of solid tumors: A meta-analysis
Jiupeng Zhou, Hui Guo, Yongfeng Zhang, Heng Liu, Quanli Dou
Medicine (Baltimore) 2022 Oct 7; 101(40): e30826. Published online 2022 Oct 7. doi: 10.1097/MD.0000000000030826
PMCID:
PMC9543024
AbstractArticlePDF–1.9M
14.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
15.
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB
Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan
EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698
PMCID:
PMC9433938
AbstractArticlePDF–9.3M
16.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
17.
Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma
Rongxing Liu, Yujie Sun, Jérémy Berthelet, Linh-Chi Bui, Ximing Xu, Mireille Viguier, Jean-Marie Dupret, Frédérique Deshayes, Fernando Rodrigues Lima
Int J Mol Sci. 2022 Jul; 23(13): 7060. Published online 2022 Jun 24. doi: 10.3390/ijms23137060
PMCID:
PMC9266312
AbstractArticlePDF–2.0M
18.
Rapid degradation of protein tyrosine phosphatase 1B in sickle cells: Possible contribution to sickle cell membrane weakening
Panae Noomuna, John M. Hausman, Ruhani Sansoya, Theodosia Kalfa, Mary Risinger, Philip S. Low
FASEB J. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: FASEB J. 2022 Jun; 36(6): e22360. doi: 10.1096/fj.202100809RR
PMCID:
PMC9215175
AbstractArticlePDF–1.0M
19.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
20.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M

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