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Select item 111083861.

β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells

Icía Santos-Zas, Uxía Gurriarán-Rodríguez, Tania Cid-Díaz, Gabriela Figueroa, Jessica González-Sánchez, Mónica Bouzo-Lorenzo, Carlos S. Mosteiro, José Señarís, Felipe F. Casanueva, Xesús Casabiell, Rosalía Gallego, Yolanda Pazos, Vincent Mouly, Jesús P. Camiña

Cell Mol Life Sci. 2016 Feb; 73(3): 617–635. Published online 2015 Jul 27. doi: 10.1007/s00018-015-1994-z

PMCID:: PMC11108386

Abstract Article PDF–7.1M

Select item 108367212.

GPR39 regulated spinal glycinergic inhibition and mechanical inflammatory pain

Hu-Hu Bai, Kang-Li Wang, Xiang-Ru Zeng, Jing Li, Yuan Li, Jia-Yu Xu, Yue Zhang, Hai-Feng Jiang, Xian Yang, Zhan-Wei Suo, Xiao-Dong Hu

Sci Adv. 2024 Feb 2; 10(5): eadj3808. Published online 2024 Feb 2. doi: 10.1126/sciadv.adj3808

PMCID:: PMC10836721

Abstract Article PDF–8.3M

Select item 101737103.

Signaling pathway mechanisms of neurological diseases induced by G protein‐coupled receptor 39

Bin Cao, Jue Wang, Juan Feng

CNS Neurosci Ther. 2023 Jun; 29(6): 1470–1483. Published online 2023 Mar 21. doi: 10.1111/cns.14174

PMCID:: PMC10173710

Abstract Article PDF–4.9M

Select item 99106114.

Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis

Sai Pranathi Meda Venkata, Hainan Li, Liping Xu, Jia Yi Koh, Huong Nguyen, Morgan Minjares, Chunying Li, Anjaneyulu Kowluru, Graeme Milligan, Jie-Mei Wang

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2208541120. Published online 2022 Dec 27. doi: 10.1073/pnas.2208541120

PMCID:: PMC9910611

Abstract Article PDF–8.3M

Select item 91857955.

Interaction between Zinc, GPR39, BDNF and Neuropeptides in Depression

Katarzyna Mlyniec

Curr Neuropharmacol. 2021 Nov 15; 19(11): 2012–2019. Published online 2021 Nov 15. doi: 10.2174/1570159X19666210225153404

PMCID:: PMC9185795

Abstract Article PDF–1.3M

Select item 80424036.

Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

Kaare V. Grunddal, Thi A. Diep, Natalia Petersen, Iain R. Tough, Louise J. Skov, Lingzhi Liu, Jesse A. Buijink, Franziska Mende, Chunyu Jin, Sara L. Jepsen, Louis M.E. Sørensen, Michael P. Achiam, Rune B. Strandby, Anders Bach, Bolette Hartmann, Thomas M. Frimurer, Siv A. Hjorth, Michel Bouvier, Helen Cox, Birgitte Holst

Mol Metab. 2021 Jul; 49: 101207. Published online 2021 Mar 9. doi: 10.1016/j.molmet.2021.101207

PMCID:: PMC8042403

Abstract Article PDF–1.8M

Select item 74608327.

Orchestration of Intracellular Circuits by G Protein-Coupled Receptor 39 for Hepatitis B Virus Proliferation

Kaku Goto, Hironori Nishitsuji, Masaya Sugiyama, Nao Nishida, Masashi Mizokami, Kunitada Shimotohno

Int J Mol Sci. 2020 Aug; 21(16): 5661. Published online 2020 Aug 7. doi: 10.3390/ijms21165661

PMCID:: PMC7460832

Abstract Article PDF–1.3M

Select item 68814338.

Zn²⁺ stimulates salivary secretions via metabotropic zinc receptor ZnR/GPR39 in human salivary gland cells

Yoon-Jung Kim, Youhwa Jo, Yeon-Hee Lee, Kyungpyo Park, Hee-Kyung Park, Se-Young Choi

Sci Rep. 2019; 9: 17648. Published online 2019 Nov 27. doi: 10.1038/s41598-019-54173-3

PMCID:: PMC6881433

Abstract Article PDF–2.5M

Select item 68509569.

microRNA‐1914, which is regulated by lncRNA DUXAP10, inhibits cell proliferation by targeting the GPR39‐mediated PI3K/AKT/mTOR pathway in HCC

Liankang Sun, Liang Wang, Tianxiang Chen, Bowen Yao, Yufeng Wang, Qing Li, Wei Yang, Zhikui Liu

J Cell Mol Med. 2019 Dec; 23(12): 8292–8304. Published online 2019 Oct 1. doi: 10.1111/jcmm.14705

PMCID:: PMC6850956

Abstract Article PDF–2.8M

Select item 597016710.

Enhanced ZnR/GPR39 Activity in Breast Cancer, an Alternative Trigger of Signaling Leading to Cell Growth

Hila Ventura-Bixenshpaner, Hila Asraf, Moumita Chakraborty, Moshe Elkabets, Israel Sekler, Kathryn M. Taylor, Michal Hershfinkel

Sci Rep. 2018; 8: 8119. Published online 2018 May 25. doi: 10.1038/s41598-018-26459-5

PMCID:: PMC5970167

Abstract Article PDF–5.6M

Select item 585566111.

The Zinc Sensing Receptor, ZnR/GPR39, in Health and Disease

Michal Hershfinkel

Int J Mol Sci. 2018 Feb; 19(2): 439. Published online 2018 Feb 1. doi: 10.3390/ijms19020439

PMCID:: PMC5855661

Abstract Article PDF–524K

Select item 555741712.

The Zn²⁺-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl⁻ absorption, via basolateral KCC1, and reduces fluid loss

Laxmi Sunuwar, Hila Asraf, Mark Donowitz, Israel Sekler, Michal Hershfinkel

Biochim Biophys Acta. Author manuscript; available in PMC 2017 Aug 15.

Published in final edited form as: Biochim Biophys Acta. 2017 Apr; 1863(4): 947–960. Published online 2017 Jan 16. doi: 10.1016/j.bbadis.2017.01.009

PMCID:: PMC5557417

Abstract Article PDF–2.8M

Select item 486873313.

The role of the obestatin/GPR39 system in human gastric adenocarcinomas

Begoña O. Alén, Saúl Leal-López, María Otero Alén, Patricia Viaño, Victoria García-Castro, Carlos S. Mosteiro, Andrés Beiras, Felipe F. Casanueva, Rosalía Gallego, Tomás García-Caballero, Jesús P. Camiña, Yolanda Pazos

Oncotarget. 2016 Feb 2; 7(5): 5957–5971. Published online 2015 Dec 22. doi: 10.18632/oncotarget.6718