PMC Links for GEO Profiles (Select 109963232) - PMC

Select item 101652731.

Itch receptor MRGPRX4 interacts with the receptor activity–modifying proteins

Ilana B. Kotliar, Emilie Ceraudo, Kevin Kemelmakher-Liben, Deena A. Oren, Emily Lorenzen, Tea Dodig-Crnković, Mizuho Horioka-Duplix, Thomas Huber, Jochen M. Schwenk, Thomas P. Sakmar

J Biol Chem. 2023 May; 299(5): 104664. Published online 2023 Mar 30. doi: 10.1016/j.jbc.2023.104664

PMCID:: PMC10165273

Abstract Article PDF–3.6M

Select item 91504352.

STRUCTURE, FUNCTION AND PHARMACOLOGY OF HUMAN ITCH GPCRs

Can Cao, Hye Jin Kang, Isha Singh, He Chen, Chengwei Zhang, Wenlei Ye, Byron W. Hayes, Jing Liu, Ryan H. Gumpper, Brian J. Bender, Samuel T. Slocum, Brian E. Krumm, Katherine Lansu, John D. McCorvy, Wesley K. Kroeze, Justin G. English, Jeffrey F. DiBerto, Reid H. J. Olsen, Xi-Ping. Huang, Shicheng Zhang, Yongfeng Liu, Kuglae Kim, Joel Karpiak, Lily Y. Jan, Soman N. Abraham, Jian Jin, Brian K. Shoichet, Jonathan F. Fay, Bryan L. Roth

Nature. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Nature. 2021 Dec; 600(7887): 170–175. Published online 2021 Nov 17. doi: 10.1038/s41586-021-04126-6

PMCID:: PMC9150435

Abstract Article PDF–2.5M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67734404.

MRGPRX4 is a bile acid receptor for human cholestatic itch

Huasheng Yu, Tianjun Zhao, Simin Liu, Qinxue Wu, Omar Johnson, Zhaofa Wu, Zihao Zhuang, Yaocheng Shi, Luxin Peng, Renxi He, Yong Yang, Jianjun Sun, Xiaoqun Wang, Haifeng Xu, Zheng Zeng, Peng Zou, Xiaoguang Lei, Wenqin Luo, Yulong Li

eLife. 2019; 8: e48431. Published online 2019 Sep 10. doi: 10.7554/eLife.48431

PMCID:: PMC6773440

Abstract Article PDF–5.7M

Select item 65350095.

MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus

James Meixiong, Chirag Vasavda, Solomon H. Snyder, Xinzhong Dong

Proc Natl Acad Sci U S A. 2019 May 21; 116(21): 10525–10530. Published online 2019 May 8. doi: 10.1073/pnas.1903316116

PMCID:: PMC6535009

Abstract Article PDF–1.0M

Select item 63771146.

An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking

Julia Kozlitina, Davide Risso, Katherine Lansu, Reid Hans Johnson Olsen, Eduardo Sainz, Donata Luiselli, Arnab Barik, Carlos Frigerio-Domingues, Luca Pagani, Stephen Wooding, Thomas Kirchner, Ray Niaura, Bryan Roth, Dennis Drayna

PLoS Genet. 2019 Feb; 15(2): e1007916. Published online 2019 Feb 15. doi: 10.1371/journal.pgen.1007916