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Select item 114835611.

FGFR3 alterations in bladder cancer: Sensitivity and resistance to targeted therapies

Maxim Noeraparast, Katarina Krajina, Renate Pichler, Dora Niedersüß‐Beke, Shahrokh F Shariat, Viktor Grünwald, Sascha Ahyai, Martin Pichler

Cancer Commun (Lond) 2024 Oct; 44(10): 1189–1208. Published online 2024 Aug 19. doi: 10.1002/cac2.12602

PMCID:: PMC11483561

Abstract Article PDF–894K

Select item 113082982.

Genome-wide open reading frame profiling identifies fibroblast growth factor signaling as a driver of PD-L1 expression in head and neck squamous cell carcinoma

Jacqueline E Mann, Joshua D. Smith, Aditi Kulkarni, Susan K. Foltin, Erin B. Scheftz, Isabel R. Murray, Elizabeth Genterblum-Miller, Collin V. Brummel, Apurva Bhangale, Rebecca C. Holesli, J. Chad Brenner

Oral Oncol. Author manuscript; available in PMC 2024 Aug 8.

Published in final edited form as: Oral Oncol. 2023 Nov; 146: 106562. Published online 2023 Sep 2. doi: 10.1016/j.oraloncology.2023.106562

PMCID:: PMC11308298

Abstract Article PDF–2.1M

Select item 111593283.

Fibroblast growth factor receptor 3 mutation in voided urine is a useful diagnostic marker and significant indicator of tumor recurrence in non‐muscle invasive bladder cancer

Makito Miyake, Kokichi Sugano, Hitomi Sugino, Kazuho Imai, Eri Matsumoto, Koshi Maeda, Shinich Fukuzono, Hiroki Ichikawa, Kiyotaka Kawashima, Kaoru Hirabayashi, Tetsuro Kodama, Hiroyuki Fujimoto, Tadao Kakizoe, Yae Kanai, Kiyohide Fujimoto, Yoshihiko Hirao

Cancer Sci. 2010 Jan; 101(1): 250–258. Published online 2009 Sep 1. doi: 10.1111/j.1349-7006.2009.01334.x

PMCID:: PMC11159328

Abstract Article PDF–631K

Select item 108983384.

Exploring FGFR3 Mutations in the Male Germline: Implications for Clonal Germline Expansions and Paternal Age-Related Dysplasias

Sofia Moura, Ingrid Hartl, Veronika Brumovska, Peter P Calabrese, Atena Yasari, Yasmin Striedner, Marina Bishara, Theresa Mair, Thomas Ebner, Gerhard J Schütz, Eva Sevcsik, Irene Tiemann-Boege

Genome Biol Evol. 2024 Feb; 16(2): evae015. Published online 2024 Feb 27. doi: 10.1093/gbe/evae015

PMCID:: PMC10898338

Abstract Article PDF–3.3M

Select item 108348755.

伴FGFR3基因突变初诊多发性骨髓瘤患者临床特征和预后分析

沈娜, 张珏, 夏园, 沈旭星, 王静, 金媛媛, 张闰, 李建勇, 陈丽娟

Zhonghua Xue Ye Xue Za Zhi. 2023 Dec; 44(12): 989–994. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2023.12.004

PMCID:: PMC10834875

Abstract Article PDF–3.7M

Select item 107627716.

The Association of P53, CK29, and FGFR3 Overexpression with the Characteristics of Urothelial Cell Carcinoma of the Bladder

Mojgan Asgari, Faezeh Firouzi, Maryam Abolhasani, Mohammad Bahadoram, Maedeh Barahman, Zahra Madjd, Mitra Mehrazma, Shakiba Hassanzadeh, Esma’il Akade

Asian Pac J Cancer Prev. 2023; 24(9): 3125–3131. doi: 10.31557/APJCP.2023.24.9.3125

PMCID:: PMC10762771

Abstract Article PDF–1.0M

Select item 107221367.

FGFR3 Alterations in Bladder Cancer Stimulate Serine Synthesis to Induce Immune-Inert Macrophages That Suppress T-cell Recruitment and Activation

Yi Ouyang, Ziwei Ou, Wenlong Zhong, Jin Yang, Sha Fu, Nengtai Ouyang, Junyu Chen, Longhao Xu, Daqin Wu, Junan Qian, Yi Lin, Tianxin Lin, Jian Huang

Cancer Res. 2023 Dec 15; 83(24): 4030–4046. Published online 2023 Sep 28. doi: 10.1158/0008-5472.CAN-23-1065

PMCID:: PMC10722136

Abstract Article PDF–38M

Select item 105461208.

Fibroblast growth factor receptor 3 mutation attenuates response to immune checkpoint blockade in metastatic urothelial carcinoma by driving immunosuppressive microenvironment

Yuxuan Song, Yun Peng, Caipeng Qin, Yulong Wang, Wenbo Yang, Yiqing Du, Tao Xu

J Immunother Cancer. 2023; 11(9): e006643. Published online 2023 Sep 30. doi: 10.1136/jitc-2022-006643

PMCID:: PMC10546120

Abstract Article PDF–4.6M

Select item 104607329.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 1027869510.

Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway

Hongqi Zhang, Gang Xiang, Jiong Li, Sihan He, Yunjia Wang, Ang Deng, Yuxiang Wang, Chaofeng Guo

Chin Med J (Engl) 2023 Jun 20; 136(12): 1468–1477. Published online 2023 May 16. doi: 10.1097/CM9.0000000000002690

PMCID:: PMC10278695

Abstract Article PDF–10M

Select item 1020381811.

Emergence of FGFR3-TACC3 fusions as a potential by-pass resistance mechanism to EGFR tyrosine kinase inhibitors in EGFR mutated NSCLC patients

Sai-Hong Ignatius Ou, Leora Horn, Marcelo Cruz, Davood Vafai, Christine M. Lovly, Allison Spradlin, Michael J. Williamson, Ibiayi Dagogo-Jack, Adrienne Johnson, Vincent A. Miller, Shirish Gadgeel, Siraj M. Ali, Alexa B. Schrock

Lung Cancer. Author manuscript; available in PMC 2023 May 23.

Published in final edited form as: Lung Cancer. 2017 Sep; 111: 61–64. Published online 2017 Jul 11. doi: 10.1016/j.lungcan.2017.07.006

PMCID:: PMC10203818

Abstract Article PDF–374K

Select item 1010652212.

Auto-Antibodies against Trisulfated Heparin Disaccharide and Fibroblast Growth Factor Receptor-3 May Play a Role in the Pathogenesis of Neuropathic Corneal Pain

Betul N. Bayraktutar, Vanessa Atocha, Khosro Farhad, Oscar Soto, Pedram Hamrah

Cornea. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Cornea. 2023 Jul 1; 42(7): 821–828. Published online 2022 Oct 17. doi: 10.1097/ICO.0000000000003142

PMCID:: PMC10106522

Abstract Article PDF–941K

Select item 1007290613.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 1002611114.

PRMT5/FGFR3/AKT Signaling Axis Facilitates Lung Cancer Cell Metastasis

Yonghua Zheng, Jingjing Lu, Xiaoyan Hu, Xiaobiao Hu, Xiwen Gao, Jie Zhou

Technol Cancer Res Treat. 2023; 22: 15330338231161139. Published online 2023 Mar 17. doi: 10.1177/15330338231161139

PMCID:: PMC10026111

Abstract Article PDF–2.5M

Select item 992482515.

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability

Clark G. Wang, Malalage N. Peiris, April N. Meyer, Katelyn N. Nelson, Daniel J. Donoghue

Oncotarget. 2023; 14: 133–145. Published online 2023 Feb 11. doi: 10.18632/oncotarget.28359

PMCID:: PMC9924825

Abstract Article PDF–3.5M

Select item 986335316.

Genetic Interference of FGFR3 Impedes Invasion of Upper Tract Urothelial Carcinoma Cells by Alleviating RAS/MAPK Signal Activity

Gong-Kai Huang, Chao-Cheng Huang, Chih-Hsiung Kang, Yuan-Tso Cheng, Po-Ching Tsai, Ying-Hsien Kao, Yueh-Hua Chung

Int J Mol Sci. 2023 Jan; 24(2): 1776. Published online 2023 Jan 16. doi: 10.3390/ijms24021776

PMCID:: PMC9863353

Abstract Article PDF–8.4M

Select item 963331417.

Fibroblast growth factor receptor 3 overexpression mediates ALK inhibitor resistance in ALK‐rearranged non–small cell lung cancer

Takuya Sakashita, Noriko Yanagitani, Sumie Koike, Siew‐Kee Low, Satoshi Takagi, Satoko Baba, Kengo Takeuchi, Makoto Nishio, Naoya Fujita, Ryohei Katayama

Cancer Sci. 2022 Nov; 113(11): 3888–3900. Published online 2022 Sep 11. doi: 10.1111/cas.15529

PMCID:: PMC9633314

Abstract Article PDF–12M

Select item 954501518.

PD‐L1 expression and FGFR‐mutations among Danish patients diagnosed with metastatic urothelial carcinoma: A retrospective and descriptive study

Trine Grantzau, Birgitte Grønkær Toft, Linea Cecilie Melchior, Johanna Elversang, Dag Rune Stormoen, Lise Høj Omland, Helle Pappot

APMIS. 2022 Aug; 130(8): 498–506. Published online 2022 Jun 15. doi: 10.1111/apm.13249

PMCID:: PMC9545015

Abstract Article PDF–153K

Select item 950500219.

FGFR1–4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer

Joanna Moes-Sosnowska, Monika Skupinska, Urszula Lechowicz, Ewa Szczepulska-Wojcik, Paulina Skronska, Adriana Rozy, Aneta Stepniewska, Renata Langfort, Piotr Rudzinski, Tadeusz Orlowski, Delfina Popiel, Aleksandra Stanczak, Maciej Wieczorek, Joanna Chorostowska-Wynimko

Int J Mol Sci. 2022 Sep; 23(18): 10506. Published online 2022 Sep 10. doi: 10.3390/ijms231810506

PMCID:: PMC9505002

Abstract Article PDF–4.2M

Select item 939116320.

The Role of the Key Differentially Mutated Gene FGFR3 in the Immune Microenvironment of Bladder Cancer

Jun Jiang, Yan Zhan, Jun Li

J Immunol Res. 2022; 2022: 7952706. Published online 2022 Aug 12. doi: 10.1155/2022/7952706

PMCID:: PMC9391163

Abstract Article PDF–3.6M

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