PMC Links for GEO Profiles (Select 109973561) - PMC

Select item 86256321.

Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage

Radim Vrzal

Int J Mol Sci. 2021 Nov; 22(22): 12306. Published online 2021 Nov 14. doi: 10.3390/ijms222212306

PMCID:: PMC8625632

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77381123.

Association between CYP2A13 polymorphisms and lung cancer: A protocol for systematic review and meta-analysis

Long Ma, Gang Jin, Yi Yang, Yao Pang, Wenhao Wang, Hongyi Zhang, Jiawei Liu, Peng Wu, Zequan Wang, Kui Wang, Ruitong Chang, Jialong Li, Zijiang Zhu

Medicine (Baltimore) 2020 Dec 11; 99(50): e23289. Published online 2020 Dec 11. doi: 10.1097/MD.0000000000023289

PMCID:: PMC7738112

Abstract Article PDF–184K

Select item 64492634.

HapMap‐based study: CYP2A13 may be a potential key metabolic enzyme gene in the carcinogenesis of lung cancer in non‐smokers

Feng Hua, Yonglu Guo, Qiang Sun, Leizhou Yang, Fang Gao

Thorac Cancer. 2019 Apr; 10(4): 601–606. Published online 2019 Feb 26. doi: 10.1111/1759-7714.12954

PMCID:: PMC6449263

Abstract Article PDF–104K

Select item 57802635.

Oxidation of 1-Chloropyrene by Human CYP1 Family and CYP2A Subfamily Cytochrome P450 Enzymes: Catalytic Roles of Two CYP1B1 and Five CYP2A13 Allelic Variants

Tsutomu Shimada, Norie Murayama, Kensaku Kakimoto, Shigeo Takenaka, Young-Ran Lim, Sora Yeom, Donghak Kim, Hiroshi Yamazaki, F. Peter Guengerich, Masayuki Komori

Xenobiotica. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Xenobiotica. 2018 Jun; 48(6): 565–575. Published online 2017 Jul 21. doi: 10.1080/00498254.2017.1347306

PMCID:: PMC5780263

Abstract Article PDF–3.7M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 44077047.

Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model

Zhihua Liu, Vandana Megaraj, Lei Li, Stewart Sell, Jing Hu, Xinxin Ding

Drug Metab Dispos. 2015 May; 43(5): 698–702. Published online 2015 May. doi: 10.1124/dmd.115.063305

PMCID:: PMC4407704

Abstract Article PDF–637K

Select item 41092098.

Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model

Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang, Xinxin Ding

Drug Metab Dispos. 2014 Aug; 42(8): 1341–1348. Published online 2014 Aug. doi: 10.1124/dmd.114.059188

PMCID:: PMC4109209

Abstract Article PDF–1.2M

Select item 38719359.

Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model

Vandana Megaraj, Xin Zhou, Fang Xie, Zhihua Liu, Weizhu Yang, Xinxin Ding

Carcinogenesis. 2014 Jan; 35(1): 131–137. Published online 2013 Aug 28. doi: 10.1093/carcin/bgt269

PMCID:: PMC3871935

Abstract Article PDF–759K

Select item 346382710.

Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells

Yu Guo, Liang-Ru Zhu, Gang Lu, Hui Wang, Jun-Yan Hong

Drug Metab Dispos. 2012 Oct; 40(10): 1878–1882. doi: 10.1124/dmd.112.046359

PMCID:: PMC3463827

Abstract Article PDF–1.1M

Select item 342254711.

Evaluation of Inhibition Selectivity for Human Cytochrome P450 2A Enzymes

Eva S. Stephens, Agnes A. Walsh, Emily E. Scott

Drug Metab Dispos. 2012 Sep; 40(9): 1797–1802. doi: 10.1124/dmd.112.045161

PMCID:: PMC3422547

Abstract Article PDF–790K

Select item 341099812.

Nicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Binding and Access Channel in Human Cytochrome P450 2A6 and 2A13 Enzymes

Natasha M. DeVore, Emily E. Scott

J Biol Chem. 2012 Aug 3; 287(32): 26576–26585. Published online 2012 Jun 14. doi: 10.1074/jbc.M112.372813

PMCID:: PMC3410998

Abstract Article PDF–2.9M

Select item 336279113.

Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model

Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao, Xinxin Ding

Drug Metab Dispos. 2012 Jun; 40(6): 1144–1150. doi: 10.1124/dmd.112.044826

PMCID:: PMC3362791

Abstract Article PDF–229K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 287525915.

Mechanisms of Differential Expression of the CYP2A13 7520C and 7520G Alleles in Human Lung: Allelic Expression Analysis for CYP2A13 Heterogeneous Nuclear RNA, and Evidence for the Involvement of Multiple Cis-Regulatory Single Nucleotide Polymorphisms

Hong Wu, Xiuling Zhang, Guoyu Ling, Jaime D’Agostino, Xinxin Ding

Pharmacogenet Genomics. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Pharmacogenet Genomics. 2009 Nov; 19(11): 852–863. doi: 10.1097/FPC.0b013e3283313aa5

PMCID:: PMC2875259

Abstract Article PDF–2.0M

Select item 259763516.

Characterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokers

Jaime D’Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu, Xinxin Ding

Drug Metab Dispos. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: Drug Metab Dispos. 2008 Nov; 36(11): 2316–2323. Published online 2008 Jul 31. doi: 10.1124/dmd.108.022822

PMCID:: PMC2597635

Abstract Article PDF–570K

Select item 180126117.

A Genetic Polymorphism in Coumarin 7-Hydroxylation: Sequence of the Human CYP2A Gnes and Identification of Variant CYP2A6 Alleles

Pedro Fernandez-Salguero, Susan M. G. Hoffman, Suzanne Cholerton, Harvey Mohrenweiser, Hannu Raunio, Arja Rautio, Olavi Pelkonen, Jin-ding Huang, William E. Evans, Jeffrey R. Idle, Frank J. Gonzalez

Am J Hum Genet. 1995 Sep; 57(3): 651–660.

PMCID:: PMC1801261

Summary Page Browse PDF–1.6M

Select item 45569618.

Genetic polymorphisms of CYP2A13 and its relationship to nasopharyngeal carcinoma in the Cantonese population

Ju-Hong Jiang, Wei-Hua Jia, Han-Kui Chen, Bing-Jian Feng, Hai-De Qin, Zhi-Gang Pan, Guo-Ping Shen, Li-Xi Huang, Qi-Sheng Feng, Li-Zhen Chen, Dong-Xin Lin, Yi-Xin Zeng

J Transl Med. 2004; 2: 24. Published online 2004 Jun 29. doi: 10.1186/1479-5876-2-24

PMCID:: PMC455696

Abstract Article PDF–310K

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