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Select item 114674361.

Novel mechanisms of MITF regulation identified in a mouse suppressor screen

Hong Nhung Vu, Matti Már Valdimarsson, Sara Sigurbjörnsdóttir, Kristín Bergsteinsdóttir, Julien Debbache, Keren Bismuth, Deborah A Swing, Jón H Hallsson, Lionel Larue, Heinz Arnheiter, Neal G Copeland, Nancy A Jenkins, Petur O Heidarsson, Eiríkur Steingrímsson

EMBO Rep. 2024 Oct; 25(10): 4252–4280. Published online 2024 Aug 21. doi: 10.1038/s44319-024-00225-3

PMCID:: PMC11467436

Abstract Article PDF–6.1M

Select item 111591162.

Low expression of microphthalmia‐associated transcription factor, a potential molecular target for interferon‐alpha susceptibility, is associated with metastasis in renal cell carcinoma

Toru Shimazui, Takahiro Kojima, Kazuhiro Yoshikawa, Yoshihiro Ami, Takehiro Oikawa, Kazuhiko Uchida, Hideyuki Akaza

Cancer Sci. 2009 Sep; 100(9): 1714–1718. Published online 2009 May 12. doi: 10.1111/j.1349-7006.2009.01216.x

PMCID:: PMC11159116

Abstract Article PDF–504K

Select item 111585113.

Simultaneous suppression of MITF and BRAF^V600E enhanced inhibition of melanoma cell proliferation

Kenji Kido, Hidetoshi Sumimoto, Sakiyo Asada, Starlyn M. Okada, Tomonori Yaguchi, Naoshi Kawamura, Makoto Miyagishi, Toshiaki Saida, Yutaka Kawakami

Cancer Sci. 2009 Oct; 100(10): 1863–1869. Published online 2009 Jun 29. doi: 10.1111/j.1349-7006.2009.01266.x

PMCID:: PMC11158511

Abstract Article PDF–2.2M

Select item 109408754.

MITF regulates the subcellular location of HIF1α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells

Minying Zheng, Shifeng Tian, Xinyue Zhou, Man Yan, Mingming Zhou, Yongjun Yu, Yue Zhang, Xiaorui Wang, Na Li, Li Ren, Shiwu Zhang

Oncol Rep. 2024 May; 51(5): 63. Published online 2024 Mar 6. doi: 10.3892/or.2024.8722

PMCID:: PMC10940875

Abstract Article PDF–17M

Select item 109332675.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 109076646.

Emerging roles of MITF as a crucial regulator of immunity

Aram Lee, Jihyun Lim, Jong-Seok Lim

Exp Mol Med. 2024 Feb; 56(2): 311–318. Published online 2024 Feb 13. doi: 10.1038/s12276-024-01175-5

PMCID:: PMC10907664

Abstract Article PDF–890K

Select item 105757817.

GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation

Koei Shinzawa, Shinji Matsumoto, Ryota Sada, Akikazu Harada, Kaori Saitoh, Keiko Kato, Satsuki Ikeda, Akiyoshi Hirayama, Kazunori Yokoi, Atsushi Tanemura, Keisuke Nimura, Masahito Ikawa, Tomoyoshi Soga, Akira Kikuchi

Oncogene. 2023; 42(42): 3142–3156. Published online 2023 Sep 1. doi: 10.1038/s41388-023-02803-6

PMCID:: PMC10575781

Abstract Article PDF–5.0M

Select item 105658768.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105393089.

Acetylation reprograms MITF target selectivity and residence time

Pakavarin Louphrasitthiphol, Alessia Loffreda, Vivian Pogenberg, Sarah Picaud, Alexander Schepsky, Hans Friedrichsen, Zhiqiang Zeng, Anahita Lashgari, Benjamin Thomas, E. Elizabeth Patton, Matthias Wilmanns, Panagis Filippakopoulos, Jean-Philippe Lambert, Eiríkur Steingrímsson, Davide Mazza, Colin R. Goding

Nat Commun. 2023; 14: 6051. Published online 2023 Sep 28. doi: 10.1038/s41467-023-41793-7

PMCID:: PMC10539308

Abstract Article PDF–3.0M

Select item 996160010.

MITF Downregulation Induces Death in Human Mast Cell Leukemia Cells and Impairs IgE-Dependent Degranulation

Elizabeth Proaño-Pérez, Laia Ollé, Yanru Guo, Cristina Aparicio, Mario Guerrero, Rosa Muñoz-Cano, Margarita Martin

Int J Mol Sci. 2023 Feb; 24(4): 3515. Published online 2023 Feb 9. doi: 10.3390/ijms24043515

PMCID:: PMC9961600

Abstract Article PDF–1.8M

Select item 991497311.

MiR-182 Is Upregulated in Prostate Cancer and Contributes to Tumor Progression by Targeting MITF

M. Y. Cynthia Stafford, Declan J. McKenna

Int J Mol Sci. 2023 Feb; 24(3): 1824. Published online 2023 Jan 17. doi: 10.3390/ijms24031824

PMCID:: PMC9914973

Abstract Article PDF–2.7M

Select item 990801112.

A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

Christopher Nardone, Brad A. Palanski, Daniel C. Scott, Richard T. Timms, Karl W. Barber, Xin Gu, Aoyue Mao, Yumei Leng, Emma V. Watson, Brenda A. Schulman, Philip A. Cole, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2023 Feb 14.

Published in final edited form as: Mol Cell. 2023 Jan 5; 83(1): 57–73.e9. doi: 10.1016/j.molcel.2022.12.013

PMCID:: PMC9908011

Abstract Article PDF–2.9M

Select item 983595413.

Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells

Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Yoon Kyung Jeon, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

J Immunother Cancer. 2023; 11(1): e005699. Published online 2023 Jan 10. doi: 10.1136/jitc-2022-005699

Correction in:: J Immunother Cancer. 2023; 11(3): e005699corr1.

PMCID:: PMC9835954

Abstract Article PDF–5.0M

Select item 974756014.

Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next‐generation sequencing

Chen‐Yu Lee, Ming‐Yu Lo, You‐Mei Chen, Pei‐Hsuan Lin, Chuan‐Jen Hsu, Pei‐Lung Chen, Chen‐Chi Wu, Jacob Shujui Hsu

Mol Genet Genomic Med. 2022 Dec; 10(12): e2082. Published online 2022 Nov 4. doi: 10.1002/mgg3.2082

PMCID:: PMC9747560

Abstract Article PDF–1009K

Select item 973892515.

SMILE Downregulation during Melanogenesis Induces MITF Transcription in B16F10 Cells

Xuan T. Truong, Young-Seung Lee, Thuy T. P. Nguyen, Hyun-Jin Kim, Sung-Hak Kim, Changjong Moon, Don-Kyu Kim, Hueng-Sik Choi, Tae-Il Jeon

Int J Mol Sci. 2022 Dec; 23(23): 15094. Published online 2022 Dec 1. doi: 10.3390/ijms232315094

PMCID:: PMC9738925

Abstract Article PDF–2.2M

Select item 968394816.

Study on the Mechanism of miR-125b-5p Affecting Melanocyte Biological Behavior and Melanogenesis in Vitiligo through Regulation of MITF

Xiaochuan Wang, Yifei Wu, Peng Du, Liangheng Xu, Yuan Chen, Jingzi Li, Xuying Pan, Zhiqiong Wang

Dis Markers. 2022; 2022: 6832680. Published online 2022 Nov 16. doi: 10.1155/2022/6832680

PMCID:: PMC9683948

Abstract Article PDF–2.1M

Select item 954504117.

The MITF regulatory network in melanoma

Jagat S. Chauhan, Michael Hölzel, Jean‐Philippe Lambert, Francesca M. Buffa, Colin R. Goding

Pigment Cell Melanoma Res. 2022 Sep; 35(5): 517–533. Published online 2022 Jul 9. doi: 10.1111/pcmr.13053

PMCID:: PMC9545041

Abstract Article PDF–15M

Select item 932430718.

MiTF/TFE Translocation Renal Cell Carcinomas: From Clinical Entities to Molecular Insights

Audrey Simonaggio, Damien Ambrosetti, Virginie Verkarre, Marie Auvray, Stéphane Oudard, Yann-Alexandre Vano

Int J Mol Sci. 2022 Jul; 23(14): 7649. Published online 2022 Jul 11. doi: 10.3390/ijms23147649

PMCID:: PMC9324307

Abstract Article PDF–1.7M

Select item 882889519.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 880048220.

Methionine oxidation of CLK4 promotes the metabolic switch and redox homeostasis in esophageal carcinoma via inhibiting MITF selective autophagy

Yaxing Shen, Heng Zhang, Shihua Yao, Feng Su, Hao Wang, Jun Yin, Yong Fang, Lijie Tan, Kaiguang Zhang, Xiangshan Fan, Ming Zhong, Qingxin Zhou, Jie He, Zhiyong Zhang

Clin Transl Med. 2022 Jan; 12(1): e719. Published online 2022 Jan 29. doi: 10.1002/ctm2.719