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Items: 1 to 20 of 31

1.
Tyrosine phosphatase STEP61 in human dementia and in animal models with amyloid and tau pathology
Deonne Taylor, Andrew Kneynsberg, Marloes van Roijen, Jürgen Götz
Mol Brain. 2023; 16: 6. Published online 2023 Jan 13. doi: 10.1186/s13041-023-00994-3
PMCID:
PMC9840288
AbstractArticlePDF–1.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan
Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura
Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186
PMCID:
PMC7657179
AbstractArticlePDF–225K
4.
Inhibition of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Activity Reverses Behavioral Deficits in a Rodent Model of Autism
Manavi Chatterjee, Priya Singh, Jian Xu, Paul J. Lombroso, Pradeep K. Kurup
Behav Brain Res. Author manuscript; available in PMC 2021 Aug 5.
Published in final edited form as: Behav Brain Res. 2020 Aug 5; 391: 112713. Published online 2020 May 24. doi: 10.1016/j.bbr.2020.112713
PMCID:
PMC7346720
AbstractArticlePDF–703K
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
7.
A Critical Role for Protein Tyrosine Phosphatase Nonreceptor Type 5 in Determining Individual Susceptibility to Develop Stress-Related Cognitive and Morphological Changes
Chih-Hao Yang, Chiung-Chun Huang, Kuei-Sen Hsu
J Neurosci. 2012 May 30; 32(22): 7550–7562. doi: 10.1523/JNEUROSCI.5902-11.2012
PMCID:
PMC6703597
AbstractArticlePDF–3.2M
8.
Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing
Annemarie Dedek, Jian Xu, Chaya M Kandegedara, Louis-Étienne Lorenzo, Antoine G Godin, Yves De Koninck, Paul J Lombroso, Eve C Tsai, Michael E Hildebrand
Brain. 2019 Jun; 142(6): 1535–1546. Published online 2019 May 28. doi: 10.1093/brain/awz105
PMCID:
PMC6536915
AbstractArticlePDF–5.9M
9.
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling
Parveen Kumar, Prathyusha Munnangi, KVS Rammohan Chowdary, Varun J. Shah, Swapnil R. Shinde, Nanci R. Kolli, Rachita R. Halehalli, Hampapathalu A. Nagarajaram, Subbareddy Maddika
J Proteome Res. 2017 Aug 4; 16(8): 2789–2801. Published online 2017 Jul 4. doi: 10.1021/acs.jproteome.7b00065
PMCID:
PMC5548413
AbstractArticlePDF–5.2M
10.
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family
Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang
Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277
PMCID:
PMC5013315
AbstractArticlePDF–3.2M
11.
PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61
Sehoon Won, Salvatore Incontro, Roger A. Nicoll, Katherine W. Roche
Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32): E4736–E4744. Published online 2016 Jul 25. doi: 10.1073/pnas.1609702113
PMCID:
PMC4987792
AbstractArticlePDF–1.5M
12.
Missense Variant in MAPK Inactivator PTPN5 Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring
Ravi F. Sood, Saman Arbabi, Shari Honari, Nicole S. Gibran
PLoS One. 2016; 11(2): e0149206. Published online 2016 Feb 12. doi: 10.1371/journal.pone.0149206
PMCID:
PMC4752497
AbstractArticlePDF–434K
13.
STEP Levels Are Unchanged in Pre-Frontal Cortex and Associative Striatum in Post-Mortem Human Brain Samples from Subjects with Schizophrenia, Bipolar Disorder and Major Depressive Disorder
Thomas A. Lanz, J. Julie Joshi, Veronica Reinhart, Kjell Johnson, Lonnie E. Grantham II, Dmitri Volfson
PLoS One. 2015; 10(3): e0121744. Published online 2015 Mar 18. doi: 10.1371/journal.pone.0121744
PMCID:
PMC4364624
AbstractArticlePDF–352K
14.
STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease
Pradeep K. Kurup, Jian Xu, Rita Alexandra Videira, Chimezie Ononenyi, Graça Baltazar, Paul J. Lombroso, Angus C. Nairn
Proc Natl Acad Sci U S A. 2015 Jan 27; 112(4): 1202–1207. Published online 2015 Jan 12. doi: 10.1073/pnas.1417423112
PMCID:
PMC4313846
AbstractArticlePDF–1.1M
15.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
16.
Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disorders
Takatoshi Karasawa, Paul J. Lombroso
Neurosci Res. Author manuscript; available in PMC 2015 Dec 1.
Published in final edited form as: Neurosci Res. 2014 Dec; 0: 1–9. Published online 2014 Sep 10. doi: 10.1016/j.neures.2014.08.018
PMCID:
PMC4259835
AbstractArticlePDF–475K
17.
Alterations in Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Expression, Activation and Downstream Signaling in Early and Late Stages of the YAC128 Huntington’s Disease Mouse Model
Clare M. Gladding, Jing Fan, Lily Y. J. Zhang, Liang Wang, Jian Xu, Edward H. Y. Li, Paul J. Lombroso, Lynn A. Raymond
J Neurochem. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: J Neurochem. 2014 Jul; 130(1): 145–159. Published online 2014 Apr 2. doi: 10.1111/jnc.12700
PMCID:
PMC4065618
AbstractArticlePDF–1.2M
18.
Involvement of PTPN5, the gene encoding the STriatal-Enriched protein tyrosine Phosphatase (STEP), in schizophrenia and cognition
Ilana Pelov, Omri Teltsh, Lior Greenbaum, Amihai Rigbi, Kyra Kanyas-Sarner, Bernard Lerer, Paul Lombroso, Yoav Kohn
Psychiatr Genet. Author manuscript; available in PMC 2013 Sep 3.
Published in final edited form as: Psychiatr Genet. 2012 Aug; 22(4): 168–176. doi: 10.1097/YPG.0b013e3283518586
PMCID:
PMC3760343
AbstractArticlePDF–401K
19.
THE TYROSINE PHOSPHATASE STEP CONSTRAINS AMYGDALA-DEPENDENT MEMORY FORMATION AND NEUROPLASTICITY
P. OLAUSSON, D. V. VENKITARAMANI, T. D. MORAN, M. W. SALTER, J. R. TAYLOR, P. J. LOMBROSO
Neuroscience. Author manuscript; available in PMC 2013 Jul 29.
Published in final edited form as: Neuroscience. 2012 Dec 6; 225: 1–8. Published online 2012 Aug 9. doi: 10.1016/j.neuroscience.2012.07.069
PMCID:
PMC3725644
AbstractArticlePDF–1.0M
20.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M

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