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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
IL-13Rα1-Mediated Signaling Regulates Age-Associated/Autoimmune B-Cell Expansion and Lupus Pathogenesis
Zhu Chen, Danny Flores Castro, Sanjay Gupta, Swati Phalke, Michela Manni, Juan Rivera-Correa, Rolf Jessberger, Habib Zaghouani, Evgenia Giannopoulou, Tania Pannellini, Alessandra B. Pernis
Arthritis Rheumatol. Author manuscript; available in PMC 2023 Sep 1.
Published in final edited form as: Arthritis Rheumatol. 2022 Sep; 74(9): 1544–1555. Published online 2022 Aug 22. doi: 10.1002/art.42146
PMCID:
PMC9427689
AbstractArticlePDF–1.2M
3.
Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice
Edd Ricker, Michela Manni, Danny Flores-Castro, Daniel Jenkins, Sanjay Gupta, Juan Rivera-Correa, Wenzhao Meng, Aaron M. Rosenfeld, Tania Pannellini, Mahesh Bachu, Yurii Chinenov, Peter K. Sculco, Rolf Jessberger, Eline T. Luning Prak, Alessandra B. Pernis
Nat Commun. 2021; 12: 4813. Published online 2021 Aug 10. doi: 10.1038/s41467-021-25102-8
PMCID:
PMC8355159
AbstractArticlePDF–7.5M
4.
Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
Zhonghao Deng, Courtney Ng, Kazuki Inoue, Ziyu Chen, Yuhan Xia, Xiaoyu Hu, Matthew Greenblatt, Alessandra Pernis, Baohong Zhao
eLife. 2020; 9: e59659. Published online 2020 Dec 29. doi: 10.7554/eLife.59659
PMCID:
PMC7771961
AbstractArticlePDF–1.2M
5.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
6.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
7.
Regulation of Age-associated B cells by IRF5 in systemic autoimmunity
Michela Manni, Sanjay Gupta, Edd Ricker, Yurii Chinenov, Sung Ho Park, Man Shi, Tania Pannellini, Rolf Jessberger, Lionel Ivashkiv, Alessandra B. Pernis
Nat Immunol. Author manuscript; available in PMC 2018 Aug 26.
Published in final edited form as: Nat Immunol. 2018 Apr; 19(4): 407–419. Published online 2018 Feb 26. doi: 10.1038/s41590-018-0056-8
PMCID:
PMC6095139
AbstractArticlePDF–1.1M
8.
Regulation of systemic autoimmunity and CD11c+ Tbet+ B cells by SWEF proteins
Michela Manni, Edd Ricker, Alessandra B. Pernis
Cell Immunol. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: Cell Immunol. 2017 Nov; 321: 46–51. Published online 2017 Jul 11. doi: 10.1016/j.cellimm.2017.05.010
PMCID:
PMC5877469
AbstractArticlePDF–519K
9.
Def-6, a Novel Regulator of Small GTPases in Podocytes, Acts Downstream of Atypical Protein Kinase C (aPKC) λ/ι
Kirstin Worthmann, Michael Leitges, Beina Teng, Marcello Sestu, Irini Tossidou, Thomas Samson, Hermann Haller, Tobias B. Huber, Mario Schiffer
Am J Pathol. 2013 Dec; 183(6): 1945–1959. doi: 10.1016/j.ajpath.2013.08.026
PMCID:
PMC5707189
AbstractArticlePDF–2.4M
10.
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity
Woelsung Yi, Sanjay Gupta, Edd Ricker, Michela Manni, Rolf Jessberger, Yurii Chinenov, Henrik Molina, Alessandra B. Pernis
Nat Commun. 2017; 8: 254. Published online 2017 Aug 15. doi: 10.1038/s41467-017-00348-3
PMCID:
PMC5557982
AbstractArticlePDF–3.5M
11.
Def6 restrains osteoclastogenesis and inflammatory bone resorption1
Nikolaus Binder, Christine Miller, Masaki Yoshida, Kazuki Inoue, Shinichi Nakano, Xiaoyu Hu, Lionel B. Ivashkiv, Georg Schett, Alessandra Pernis, Steven R. Goldring, F. Patrick Ross, Baohong Zhao
J Immunol. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: J Immunol. 2017 May 1; 198(9): 3436–3447. Published online 2017 Mar 17. doi: 10.4049/jimmunol.1601716
PMCID:
PMC5425156
AbstractArticlePDF–2.3M
12.
SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells
Tatsiana Ripich, Carlos Andrés Chacón-Martínez, Luise Fischer, Alessandra Pernis, Nadine Kiessling, Annette I. Garbe, Rolf Jessberger
PLoS One. 2016; 11(8): e0161060. Published online 2016 Aug 25. doi: 10.1371/journal.pone.0161060
PMCID:
PMC4999197
AbstractArticlePDF–2.6M
13.
SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1
Marjorie Côte, Camille Fos, Ann J. Canonigo-Balancio, Klaus Ley, Stéphane Bécart, Amnon Altman
J Cell Sci. 2015 Dec 1; 128(23): 4341–4352. doi: 10.1242/jcs.172742
PMCID:
PMC4712813
AbstractArticle
14.
IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus
Michela Manni, Sanjay Gupta, Briana G. Nixon, Casey T. Weaver, Rolf Jessberger, Alessandra B. Pernis
PLoS One. 2015; 10(11): e0141927. Published online 2015 Nov 6. doi: 10.1371/journal.pone.0141927
PMCID:
PMC4636285
AbstractArticlePDF–3.3M
15.
Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP3 receptor 1 promotes Ca2+ signaling in T cells
Camille Fos, Stephane Becart, Ann J. Canonigo Balancio, Darren Boehning, Amnon Altman
Sci Signal. Author manuscript; available in PMC 2015 Jan 20.
Published in final edited form as: Sci Signal. 2014 Sep 30; 7(345): ra93. Published online 2014 Sep 30. doi: 10.1126/scisignal.2005565
PMCID:
PMC4300114
AbstractArticlePDF–1.3M
16.
SLAT Negatively Regulates RANKL-Induced Osteoclast Differentiation
Bang Ung Youn, Kabsun Kim, Jung Ha Kim, Jongwon Lee, Jang Bae Moon, Inyoung Kim, Yong-Wook Park, Nacksung Kim
Mol Cells. 2013 Sep 30; 36(3): 252–257. Published online 2013 Aug 29. doi: 10.1007/s10059-013-0159-x
PMCID:
PMC3887978
AbstractArticlePDF–9.1M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
SLAT regulates CD8+ T cell clonal expansion in a Cdc42 and NFAT1 dependent manner
Sonia Feau, Stephen P. Schoenberger, Amnon Altman, Stéphane Bécart
J Immunol. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: J Immunol. 2013 Jan 1; 190(1): 174–183. Published online 2012 Nov 28. doi: 10.4049/jimmunol.1201685
PMCID:
PMC3529792
AbstractArticlePDF–3.3M
19.
SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU)
Barbara P. Vistica, Guangpu Shi, Lindsey Nugent, Cuiyan Tan, Amnon Altman, Igal Gery
Mol Vis. 2012; 18: 1858–1864. Published online 2012 Jul 7.
PMCID:
PMC3398495
AbstractArticlePDF–950K
20.
Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity
Partha S. Biswas, Sanjay Gupta, Roslynn A. Stirzaker, Varsha Kumar, Rolf Jessberger, Theresa T. Lu, Govind Bhagat, Alessandra B. Pernis
J Exp Med. 2012 Mar 12; 209(3): 581–596. doi: 10.1084/jem.20111195
PMCID:
PMC3302237
AbstractArticlePDF–2.9M

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