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Items: 1 to 20 of 23

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Amphiregulin normalizes altered circuit connectivity for social dominance of the CRTC3 knockout mouse
Ji-Seon Park, Hwon Heo, Min-Seok Kim, Seung-Eun Lee, Sukyoung Park, Ki-Hyun Kim, Young-Ho Kang, Je Seong Kim, Young Hoon Sung, Woo Hyun Shim, Dong-Hou Kim, Youngsup Song, Seung-Yong Yoon
Mol Psychiatry. 2023; 28(11): 4655–4665. Published online 2023 Sep 20. doi: 10.1038/s41380-023-02258-x
PMCID:
PMC10914624
AbstractArticlePDF–3.0M
3.
Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways
Jelena Ostojić, Young-Sil Yoon, Tim Sonntag, Billy Nguyen, Joan M. Vaughan, Maxim Shokhirev, Marc Montminy
Cell Rep. Author manuscript; available in PMC 2022 Nov 21.
Published in final edited form as: Cell Rep. 2021 May 18; 35(7): 109136. doi: 10.1016/j.celrep.2021.109136
PMCID:
PMC9678241
AbstractArticlePDF–2.0M
4.
CRTC3, a sensor and key regulator for melanogenesis, as a tunable therapeutic target for pigmentary disorders
Hanju Yoo, Ha-Ri Lee, Ki-Hyun Kim, Min-Ah Kim, Seunghyun Bang, Young-Ho Kang, Woo-hyung Kim, Youngsup Song, Sung Eun Chang
Theranostics. 2021; 11(20): 9918–9936. Published online 2021 Oct 17. doi: 10.7150/thno.66378
PMCID:
PMC8581419
AbstractArticlePDF–3.4M
5.
Activation of the adipocyte CREB/CRTC pathway in obesity
Young-Sil Yoon, Weiyi Liu, Sam Van de Velde, Shigenobu Matsumura, Ezra Wiater, Ling Huang, Marc Montminy
Commun Biol. 2021; 4: 1214. Published online 2021 Oct 22. doi: 10.1038/s42003-021-02735-5
PMCID:
PMC8536733
AbstractArticlePDF–2.5M
6.
Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment
Tim Sonntag, Jelena Ostojić, Joan M. Vaughan, James J. Moresco, Young-Sil Yoon, John R. Yates, III, Marc Montminy
iScience. 2019 Jan 25; 11: 134–145. Published online 2018 Dec 19. doi: 10.1016/j.isci.2018.12.012
PMCID:
PMC6317279
AbstractArticlePDF–6.2M
7.
cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis
Young-Sil Yoon, Wen-Wei Tsai, Sam Van de Velde, Zhijiang Chen, Kuo-Fen Lee, Donald A. Morgan, Kamal Rahmouni, Shigenobu Matsumura, Ezra Wiater, Youngsup Song, Marc Montminy
Proc Natl Acad Sci U S A. 2018 Jun 5; 115(23): E5289–E5297. Published online 2018 May 21. doi: 10.1073/pnas.1805257115
PMCID:
PMC6003335
AbstractArticlePDF–1.5M
8.
CREB coactivators CRTC2 and CRTC3 modulate bone marrow hematopoiesis
Jeong-Ho Kim, Susan Hedrick, Wen-Wei Tsai, Ezra Wiater, John Le Lay, Klaus H. Kaestner, Mathias Leblanc, Andrew Loar, Marc Montminy
Proc Natl Acad Sci U S A. 2017 Oct 31; 114(44): 11739–11744. Published online 2017 Oct 16. doi: 10.1073/pnas.1712616114
PMCID:
PMC5676928
AbstractArticlePDF–1.0M
9.
Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members
Tim Sonntag, James J. Moresco, Joan M. Vaughan, Shigenobu Matsumura, John R. Yates, III, Marc Montminy
PLoS One. 2017; 12(2): e0173013. Published online 2017 Feb 24. doi: 10.1371/journal.pone.0173013
PMCID:
PMC5325614
AbstractArticlePDF–3.2M
10.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
11.
MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3
P Hallenborg, M Siersbæk, I Barrio-Hernandez, R Nielsen, K Kristiansen, S Mandrup, L Grøntved, B Blagoev
Cell Death Dis. 2016 Jun; 7(6): e2289. Published online 2016 Jun 30. doi: 10.1038/cddis.2016.188
PMCID:
PMC5108339
AbstractArticlePDF–2.7M
12.
Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3
Tizhong Shan, Yan Xiong, Pengpeng Zhang, Zhiguo Li, Qingyang Jiang, Pengpeng Bi, Feng Yue, Gongshe Yang, Yizhen Wang, Xiaoqi Liu, Shihuan Kuang
Nat Commun. 2016; 7: 12205. Published online 2016 Jul 27. doi: 10.1038/ncomms12205
PMCID:
PMC4974456
AbstractArticlePDF–1.8M
13.
CREB pathway links PGE2 signaling with macrophage polarization
Bing Luan, Young-Sil Yoon, John Le Lay, Klaus H. Kaestner, Susan Hedrick, Marc Montminy
Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51): 15642–15647. Published online 2015 Dec 7. doi: 10.1073/pnas.1519644112
PMCID:
PMC4697393
AbstractArticlePDF–1.0M
14.
Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4
Bing Luan, Mark O. Goodarzi, Naomi G. Phillips, Xiuqing Guo, Yii-Der I. Chen, Jie Yao, Matthew Allison, Jerome I. Rotter, Reuben Shaw, Marc Montminy
Cell Metab. Author manuscript; available in PMC 2015 Jun 3.
Published in final edited form as: Cell Metab. 2014 Jun 3; 19(6): 1058–1065. Published online 2014 Apr 24. doi: 10.1016/j.cmet.2014.03.024
PMCID:
PMC4207085
AbstractArticlePDF–1.4M
15.
Creb coactivators direct anabolic responses and enhance performance of skeletal muscle
Nelson E Bruno, Kimberly A Kelly, Richard Hawkins, Mariam Bramah-Lawani, Antonio L Amelio, Jerome C Nwachukwu, Kendall W Nettles, Michael D Conkright
EMBO J. 2014 May 2; 33(9): 1027–1043. Published online 2014 Mar 27. doi: 10.1002/embj.201386145
PMCID:
PMC4193935
AbstractArticlePDF–2.5M
16.
Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects
Kim Ravnskjaer, Meghan F. Hogan, Denise Lackey, Laszlo Tora, Sharon Y.R. Dent, Jerrold Olefsky, Marc Montminy
J Clin Invest. 2013 Oct 1; 123(10): 4318–4328. Published online 2013 Sep 24. doi: 10.1172/JCI69035
PMCID:
PMC3784539
AbstractArticlePDF–1.9M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Role of cAMP-responsive Element-binding Protein (CREB)-regulated Transcription Coactivator 3 (CRTC3) in the Initiation of Mitochondrial Biogenesis and Stress Response in Liver Cells
Tin Aung Than, Huan Lou, Cheng Ji, Sanda Win, Neil Kaplowitz
J Biol Chem. 2011 Jun 24; 286(25): 22047–22054. Published online 2011 May 2. doi: 10.1074/jbc.M111.240481
PMCID:
PMC3121349
AbstractArticlePDF–1.1M
20.
The CREB Coactivator CRTC3 Links Catecholamine Signaling to Energy Balance
Youngsup Song, Judith Altarejos, Mark O. Goodarzi, Hiroshi Inoue, Xiuqing Guo, Rebecca Berdeaux, Jeong-Ho Kim, Jason Goode, Motoyuki Igata, Jose Paz, Meghan F. Hogan, Pankaj K. Singh, Naomi Goebel, Lili Vera, Nina Miller, Jinrui Cui, Michelle R. Jones, CHARGE Consortium, GIANT Consortium, Yii-Der I. Chen, Kent D. Taylor, Willa A. Hsueh, Jerome I. Rotter, Marc Montminy
Nature. Author manuscript; available in PMC 2011 Dec 16.
Published in final edited form as: Nature. 2010 Dec 16; 468(7326): 933–939. doi: 10.1038/nature09564
PMCID:
PMC3025711
AbstractArticlePDF–1.6M

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