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Items: 1 to 20 of 87

1.
Type 2-like polarization and elevated CXCL4 secretion of monocyte derived macrophages upon internalization of plasma-derived exosomes from head and neck cancer patients
Marie-Nicole Theodoraki, Diana Huber, Linda Hofmann, Lotte Werner, Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lutz Schütt, Cornelia Brunner, Reinhard Depping, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
BMC Cancer. 2024; 24: 1173. Published online 2024 Sep 20. doi: 10.1186/s12885-024-12948-6
PMCID:
PMC11414076
AbstractArticlePDF–3.4M
2.
The Binding of the SARS-CoV-2 Spike Protein to Platelet Factor 4: A Proposed Mechanism for the Generation of Pathogenic Antibodies
Thi-Huong Nguyen, Li-Yu Chen, Nida Zaman Khan, Annerose Lindenbauer, Van-Chien Bui, Peter F. Zipfel, Doris Heinrich
Biomolecules. 2024 Mar; 14(3): 245. Published online 2024 Feb 20. doi: 10.3390/biom14030245
PMCID:
PMC10967930
AbstractArticlePDF–2.1M
3.
PF4 activates the c-Mpl–Jak2 pathway in platelets
Richard J. Buka, Samantha J. Montague, Luis A. Moran, Eleyna M. Martin, Alexandre Slater, Steve P. Watson, Phillip L. R. Nicolson
Blood. 2024 Jan 4; 143(1): 64–69. Published online 2023 Oct 29. doi: 10.1182/blood.2023020872
PMCID:
PMC10862235
AbstractArticle
4.
Platelet factor 4 induces bone loss by inhibiting the integrin α5‐FAK‐ERK pathway
Wei Li, Qiwei Zhang, Ranli Gu, Lijun Zeng, Hao Liu
Animal Model Exp Med. 2023 Dec; 6(6): 573–584. Published online 2023 Aug 11. doi: 10.1002/ame2.12342
PMCID:
PMC10757219
AbstractArticlePDF–40M
5.
Platelet factor 4 limits neutrophil extracellular trap– and cell-free DNA–induced thrombogenicity and endothelial injury
Anh T.P. Ngo, Abigail Skidmore, Jenna Oberg, Irene Yarovoi, Amrita Sarkar, Nate Levine, Veronica Bochenek, Guohua Zhao, Lubica Rauova, M. Anna Kowalska, Kaitlyn Eckart, Nilam S. Mangalmurti, Ann Rux, Douglas B. Cines, Mortimer Poncz, Kandace Gollomp
JCI Insight. 2023 Nov 22; 8(22): e171054. Published online 2023 Nov 22. doi: 10.1172/jci.insight.171054
PMCID:
PMC10721321
AbstractArticlePDF–1.1M
6.
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner
Konrad Hoeft, Gideon J.L. Schaefer, Hyojin Kim, David Schumacher, Tore Bleckwehl, Qingqing Long, Barbara Mara Klinkhammer, Fabian Peisker, Lars Koch, James Nagai, Maurice Halder, Susanne Ziegler, Elisa Liehn, Christoph Kuppe, Jennifer Kranz, Sylvia Menzel, Ivan Costa, Adam Wahida, Peter Boor, Rebekka K. Schneider, Sikander Hayat, Rafael Kramann
Cell Rep. 2023 Feb 28; 42(2): 112131. Published online 2023 Feb 18. doi: 10.1016/j.celrep.2023.112131
PMCID:
PMC9992450
AbstractArticle
7.
CXCL4-RNA Complexes Circulate in Systemic Sclerosis and Amplify Inflammatory/Pro-Fibrotic Responses by Myeloid Dendritic Cells
Immacolata Pietraforte, Alessia Butera, Lucia Gaddini, Anna Mennella, Raffaella Palazzo, Doriana Campanile, Katia Stefanantoni, Valeria Riccieri, Roberto Lande, Loredana Frasca
Int J Mol Sci. 2023 Jan; 24(1): 653. Published online 2022 Dec 30. doi: 10.3390/ijms24010653
PMCID:
PMC9820649
AbstractArticlePDF–2.8M
8.
Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts
Hoa T. Le, Kalyan Golla, Ryan Karimi, Michael R. Hughes, Flavia Lakschevitz, Douglas B. Cines, M. Anna Kowalska, Mortimer Poncz, Kelly M. McNagny, Lari Häkkinen, Hugh Kim
Sci Rep. 2022; 12: 18636. Published online 2022 Nov 3. doi: 10.1038/s41598-022-19850-w
PMCID:
PMC9633774
AbstractArticlePDF–1.8M
9.
High levels of PF4, VEGF-A, and classical monocytes correlate with the platelets count and inflammation during active tuberculosis
Alexia Urbán-Solano, Julio Flores-Gonzalez, Alfredo Cruz-Lagunas, Gloria Pérez-Rubio, Ivette Buendia-Roldan, Lucero A. Ramón-Luing, Leslie Chavez-Galan
Front Immunol. 2022; 13: 1016472. Published online 2022 Oct 17. doi: 10.3389/fimmu.2022.1016472
PMCID:
PMC9618821
AbstractArticlePDF–4.8M
10.
Urine ALCAM, PF4 and VCAM-1 Surpass Conventional Metrics in Identifying Nephritis Disease Activity in Childhood-Onset Systemic Lupus Erythematosus
Samar A. Soliman, Anam Haque, Kamala Vanarsa, Ting Zhang, Faten Ismail, Kyung Hyun Lee, Claudia Pedroza, Larry A. Greenbaum, Sherene Mason, M. John Hicks, Scott E. Wenderfer, Chandra Mohan
Front Immunol. 2022; 13: 885307. Published online 2022 May 26. doi: 10.3389/fimmu.2022.885307
PMCID:
PMC9204340
AbstractArticlePDF–3.0M
11.
CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes
Chao Yang, Mahesh Bachu, Yong Du, Caroline Brauner, Ruoxi Yuan, Marie Dominique Ah Kioon, Giancarlo Chesi, Franck J. Barrat, Lionel B. Ivashkiv
Nat Commun. 2022; 13: 3426. Published online 2022 Jun 14. doi: 10.1038/s41467-022-31132-7
PMCID:
PMC9195402
AbstractArticlePDF–3.4M
12.
Thrombospondin-1, Platelet Factor 4, and Galectin-1 are Associated with Engraftment in Patients with Sickle Cell Disease Who Underwent Haploidentical HSCT
Ahmad Shaikh, Purevdorj B. Olkhanud, Arunakumar Gangaplara, Abdoul Kone, Sajni Patel, Marjan Gucek, Courtney D. Fitzhugh
Transplant Cell Ther. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Transplant Cell Ther. 2022 May; 28(5): 249.e1–249.e13. Published online 2022 Feb 4. doi: 10.1016/j.jtct.2022.01.027
PMCID:
PMC9176382
AbstractArticlePDF–1.3M
13.
Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells
Dawid M. Kaczor, Rafael Kramann, Tilman M. Hackeng, Leon J. Schurgers, Rory R. Koenen
Int J Mol Sci. 2022 Jan; 23(2): 580. Published online 2022 Jan 6. doi: 10.3390/ijms23020580
PMCID:
PMC8775478
AbstractArticlePDF–4.1M
14.
Chemokines modulate glycan binding and the immunoregulatory activity of galectins
Lucía Sanjurjo, Iris A. Schulkens, Pauline Touarin, Roy Heusschen, Ed Aanhane, Kitty C. M. Castricum, Tanja D. De Gruijl, Ulf J. Nilsson, Hakon Leffler, Arjan W. Griffioen, Latifa Elantak, Rory R. Koenen, Victor L. J. L. Thijssen
Commun Biol. 2021; 4: 1415. Published online 2021 Dec 20. doi: 10.1038/s42003-021-02922-4
PMCID:
PMC8688422
AbstractArticlePDF–2.7M
15.
Interactions of Spike-RBD of SARS-CoV-2 and Platelet Factor 4: New Insights in the Etiopathogenesis of Thrombosis
Margherita Passariello, Cinzia Vetrei, Felice Amato, Claudia De Lorenzo
Int J Mol Sci. 2021 Aug; 22(16): 8562. Published online 2021 Aug 9. doi: 10.3390/ijms22168562
PMCID:
PMC8395316
AbstractArticlePDF–9.5M
16.
Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells
Annemiek Dickhout, Dawid M. Kaczor, Alexandra C. A. Heinzmann, Sanne L. N. Brouns, Johan W. M. Heemskerk, Marc A. M. J. van Zandvoort, Rory R. Koenen
Int J Mol Sci. 2021 Jul; 22(14): 7332. Published online 2021 Jul 8. doi: 10.3390/ijms22147332
PMCID:
PMC8305033
AbstractArticlePDF–4.4M
17.
CD8+ T cells inhibit metastasis and CXCL4 regulates its function
Robiya Joseph, Rama Soundararajan, Suhas Vasaikar, Fei Yang, Kendra L. Allton, Lin Tian, Petra den Hollander, Sevinj Isgandarova, Monika Haemmerle, Barbara Mino, Tieling Zhou, Crystal Shin, Melisa Martinez-Paniagua, Aysegul A. Sahin, Jaime Rodriguez-Canales, Juri Gelovani, Jeffrey T. Chang, Ghanashyam Acharya, Anil K. Sood, Ignacio I. Wistuba, Don L. Gibbons, Luisa M. Solis, Michelle C. Barton, Navin Varadarajan, Jeffrey M. Rosen, Xiang H. Zhang, Sendurai A. Mani
Br J Cancer. 2021 Jul 20; 125(2): 176–189. Published online 2021 Apr 1. doi: 10.1038/s41416-021-01338-5
PMCID:
PMC8292398
AbstractArticlePDF–4.1M
18.
The complicated relationships of heparin‐induced thrombocytopenia and platelet factor 4 antibodies with COVID‐19
Emmanuel J. Favaloro, Brandon Michael Henry, Giuseppe Lippi
Int J Lab Hematol. 2021 Aug; 43(4): 547–558. Published online 2021 May 17. doi: 10.1111/ijlh.13582
PMCID:
PMC8239595
AbstractArticlePDF–1.0M
19.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
20.
Reduced CXCL4/PF4 expression as a driver of increased human hematopoietic stem and progenitor cell proliferation in polycythemia vera
Fabienne Meier-Abt, Witold E. Wolski, Ge Tan, Sandra Kummer, Sabine Amon, Markus G. Manz, Ruedi Aebersold, Alexandre P. A. Theocharides
Blood Cancer J. 2021 Feb; 11(2): 31. Published online 2021 Feb 11. doi: 10.1038/s41408-021-00423-5
PMCID:
PMC7878875
ArticlePDF–1.2M

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