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Items: 1 to 20 of 72

1.
Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif
Jason Ecard, Yen-Ling Lian, Séverine Divoux, Zelia Gouveia, Emmanuelle Vigne, Franck Perez, Gaelle Boncompain
Mol Biol Cell. 2024 Mar 1; 35(3): ar42. Published online 2024 Feb 5. doi: 10.1091/mbc.E23-06-0251
PMCID:
PMC10916873
AbstractArticlePDF–1.9M
2.
Enterovirus A71 does not meet the uncoating receptor SCARB2 at the cell surface
Yorihiro Nishimura, Kei Sato, Yoshio Koyanagi, Takaji Wakita, Masamichi Muramatsu, Hiroyuki Shimizu, Jeffrey M. Bergelson, Minetaro Arita
PLoS Pathog. 2024 Feb; 20(2): e1012022. Published online 2024 Feb 15. doi: 10.1371/journal.ppat.1012022
PMCID:
PMC10901359
AbstractArticlePDF–3.0M
3.
SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activity
Feng Wang, Yang Gao, Situ Xue, Luyao Zhao, Huimin Jiang, Tingting Zhang, Yunxuan Li, Chenxi Zhao, Fan Wu, Tana Siqin, Ying Liu, Jie Wu, Yechao Yan, Jian Yuan, Jian-dong Jiang, Ke Li
Nat Commun. 2023; 14: 5917. Published online 2023 Sep 22. doi: 10.1038/s41467-023-41593-z
PMCID:
PMC10517016
AbstractArticlePDF–9.4M
4.
The effects of SCARB2 and SELPLG gene polymorphisms on EV71 infection in hand, foot, and mouth disease
Fengyuan Duan, Zengqing Du, Yang Wang, Lan Luo, Lijiang Du, Hong Jiang, Yantuanjin Ma, Yuling Yang
Biomol Biomed. 2023 Oct 1; 23(5): 815–824. Published online 2023 Oct 1. doi: 10.17305/bb.2023.8948
PMCID:
PMC10494856
AbstractArticlePDF–2.1M
5.
LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma
Yuantong Liu, Shujin Li, Shuo Wang, Qichao Yang, Zhizhong Wu, Mengjie Zhang, Lei Chen, Zhijun Sun
Int J Oral Sci. 2023; 15: 24. Published online 2023 Jun 8. doi: 10.1038/s41368-023-00229-0
PMCID:
PMC10250453
AbstractArticlePDF–14M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
Human SCARB2 Acts as a Cellular Associator for Helping Coxsackieviruses A10 Infection
Shu-Ling Yu, Nai-Hsiang Chung, Yu-Ching Lin, Yi-An Liao, Ying-Chin Chen, Yen-Hung Chow
Viruses. 2023 Apr; 15(4): 932. Published online 2023 Apr 8. doi: 10.3390/v15040932
PMCID:
PMC10144829
AbstractArticlePDF–3.0M
8.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
9.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
10.
SLC35B2 Acts in a Dual Role in the Host Sulfation Required for EV71 Infection
Dong Guo, Xinghai Yu, Dan Wang, Zhifei Li, Yu Zhou, Guodong Xu, Bing Yuan, Yali Qin, Mingzhou Chen
J Virol. 2022 May; 96(9): e02042-21. Published online 2022 Apr 14. doi: 10.1128/jvi.02042-21
PMCID:
PMC9093107
AbstractArticlePDF–6.5M
11.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
12.
A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing
Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl
Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2
PMCID:
PMC8894380
AbstractArticlePDF–5.6M
13.
TRIP12 Ubiquitination of Glucocerebrosidase Contributes to Neurodegeneration in Parkinson’s Disease
Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi-Xun Ma, Seung-Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae-In Kam, Kwangsoo Kim, Senthilkumar S Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding-Ochoa, Olga Pletnikova, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko
Neuron. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3758–3774.e11. Published online 2021 Oct 12. doi: 10.1016/j.neuron.2021.09.031
PMCID:
PMC8639668
AbstractArticlePDF–2.6M
14.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
15.
Enterovirus A71 Induces Neurological Diseases and Dynamic Variants in Oral Infection of Human SCARB2-Transgenic Weaned Mice
Jing-Yi Lin, Kuo-Feng Weng, Chih-Kuang Chang, Yu-Nong Gong, Guo-Jen Huang, Hui-Lan Lee, Yen-Cheng Chen, Chien-Chih Huang, Jia-Ying Lu, Peng-Nien Huang, Huan-Jung Chiang, Che-Min Chen, Shin-Ru Shih
J Virol. 2021 Nov; 95(21): e00897-21. Prepublished online 2021 Aug 11. Published online 2021 Oct 13. doi: 10.1128/JVI.00897-21
PMCID:
PMC8513470
AbstractArticlePDF–5.8M
16.
Class B Scavenger Receptors BI and BII Protect against LPS-Induced Acute Lung Injury in Mice by Mediating LPS
Irina N. Baranova, Alexander V. Bocharov, Tatyana G. Vishnyakova, Zhigang Chen, Anna A. Birukova, Yunbo Ke, Xuzhen Hu, Peter S. T. Yuen, Robert A. Star, Konstantin G. Birukov, Amy P. Patterson, Thomas L. Eggerman
Infect Immun. 2021 Oct; 89(10): e00301-21. Prepublished online 2021 Jun 7. Published online 2021 Sep 16. doi: 10.1128/IAI.00301-21
Correction in:
Infect Immun. 2022 Oct; 90(10): e00404-22.
PMCID:
PMC8445172
AbstractArticlePDF–1.7M
17.
Relationship between polymorphism of receptor SCARB2 gene and clinical severity of enterovirus-71 associated hand-foot-mouth disease
Xia Wang, Hong Liu, Ying Li, Rui Su, Yamin Liu, Kunyan Qiao
Virol J. 2021; 18: 132. Published online 2021 Jun 30. doi: 10.1186/s12985-021-01605-0
PMCID:
PMC8244142
AbstractArticlePDF–1009K
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice
Martijn J. C. van der Lienden, Jan Aten, André R. A. Marques, Ingeborg S. E. Waas, Per W. B. Larsen, Nike Claessen, Nicole N. van der Wel, Roelof Ottenhoff, Marco van Eijk, Johannes M. F. G. Aerts
Int J Mol Sci. 2021 Mar; 22(5): 2532. Published online 2021 Mar 3. doi: 10.3390/ijms22052532
PMCID:
PMC7959463
AbstractArticlePDF–8.7M
20.
Fibroblasts from idiopathic Parkinson’s disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2
Ria Thomas, Elizabeth B. Moloney, Zachary K. Macbain, Penelope J. Hallett, Ole Isacson
Mol Brain. 2021; 14: 16. Published online 2021 Jan 19. doi: 10.1186/s13041-020-00712-3
PMCID:
PMC7816505
AbstractArticlePDF–991K

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