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Select item 108379931.

DNMT3L inhibits hepatocellular carcinoma progression through DNA methylation of CDO1: insights from big data to basic research

Xiaokai Yan, Yao Qi, Xinyue Yao, Nanjing Zhou, Xinxin Ye, Xing Chen

J Transl Med. 2024; 22: 128. Published online 2024 Feb 2. doi: 10.1186/s12967-024-04939-9

PMCID:: PMC10837993

Abstract Article PDF–8.6M

Select item 105172122.

Targeted demethylation of the CDO1 promoter based on CRISPR system inhibits the malignant potential of breast cancer cells

Jiaojiao Yang, Liyue Sun, Xiao‐Yun Liu, Chan Huang, Junling Peng, Xinxin Zeng, Hailin Zheng, Wenjian Cen, Yu‐Xia Xu, Weijie Zhu, Xiao‐Yan Wu, Dongyi Ling, Lu‐Lu Zhang, Mingbiao Wei, Ye Liu, Deshen Wang, Feng‐Hua Wang, Yu‐Hong Li, Qin Li, Ziming Du

Clin Transl Med. 2023 Sep; 13(9): e1423. Published online 2023 Sep 22. doi: 10.1002/ctm2.1423

PMCID:: PMC10517212

Abstract Article PDF–6.1M

Select item 95354163.

Adipose tissue cysteine dioxygenase type 1 is associated with an anti-inflammatory profile, impacting on systemic metabolic traits

Jèssica Latorre, Jordi Mayneris-Perxachs, Núria Oliveras-Cañellas, Francisco Ortega, Ferran Comas, José Manuel Fernández-Real, José María Moreno-Navarrete

eBioMedicine. 2022 Nov; 85: 104302. Published online 2022 Oct 4. doi: 10.1016/j.ebiom.2022.104302

PMCID:: PMC9535416

Abstract Article PDF–1.8M

Select item 92792854.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74426016.

Detection of promoter DNA methylation in urine and plasma aids the detection of non-small cell lung cancer

Bin Liu, Julio Ricarte Filho, Apurva Mallisetty, Cassandra Villani, Anastasia Kottorou, Kristen Rodgers, Chen Chen, Tomoaki Ito, Kyla Holmes, Nicole Gastala, Klara Valyi-Nagy, Odile David, Ron C. Gaba, Christian Ascoli, Mary Pasquinelli, Lawrence E. Feldman, Malek G. Massad, Tza-Huei Wang, Ignacio Jusue-Torres, Enrico Benedetti, Robert A. Winn, Malcolm V. Brock, James G. Herman, Alicia Hulbert

Clin Cancer Res. Author manuscript; available in PMC 2021 Feb 15.

Published in final edited form as: Clin Cancer Res. 2020 Aug 15; 26(16): 4339–4348. Published online 2020 May 19. doi: 10.1158/1078-0432.CCR-19-2896

PMCID:: PMC7442601

Abstract Article PDF–688K

Select item 70501037.

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen

Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794

PMCID:: PMC7050103

Abstract Article PDF–1.8M

Select item 67781378.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 67266959.

Diagnostic potential of hypermethylation of the cysteine dioxygenase 1 gene (CDO1) promoter DNA in pancreatic cancer

Nobuyuki Nishizawa, Hiroki Harada, Yusuke Kumamoto, Takashi Kaizu, Hiroshi Katoh, Hiroshi Tajima, Hideki Ushiku, Keigo Yokoi, Kazuharu Igarashi, Yoshiki Fujiyama, Kosuke Okuwaki, Tomohisa Iwai, Masahiko Watanabe, Keishi Yamashita

Cancer Sci. 2019 Sep; 110(9): 2846–2855. Published online 2019 Aug 10. doi: 10.1111/cas.14134

PMCID:: PMC6726695

Abstract Article PDF–1004K

Select item 665889010.

Probing the Tyr-Cys Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine

Jiasong Li, Teruaki Koto, Ian Davis, Aimin Liu

Biochemistry. Author manuscript; available in PMC 2020 Jan 30.

Published in final edited form as: Biochemistry. 2019 Apr 30; 58(17): 2218–2227. Published online 2019 Apr 19. doi: 10.1021/acs.biochem.9b00006

PMCID:: PMC6658890

Abstract Article PDF–862K

Select item 658470211.

Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer

Yun Pyo Kang, Laura Torrente, Aimee Falzone, Cody M Elkins, Min Liu, John M Asara, Christian C Dibble, Gina M DeNicola

eLife. 2019; 8: e45572. Published online 2019 May 20. doi: 10.7554/eLife.45572

Correction in:: eLife. 2019; 8: e52671.

PMCID:: PMC6584702

Abstract Article PDF–2.4M

Select item 644316912.

Cancer-specific promoter DNA methylation of Cysteine dioxygenase type 1 (CDO1) gene as an important prognostic biomarker of gastric cancer

Hiroki Harada, Kei Hosoda, Hiromitsu Moriya, Hiroaki Mieno, Akira Ema, Hideki Ushiku, Marie Washio, Nobuyuki Nishizawa, Satoru Ishii, Kazuko Yokota, Yoko Tanaka, Takeshi Kaida, Takafumi Soeno, Yoshimasa Kosaka, Masahiko Watanabe, Keishi Yamashita

PLoS One. 2019; 14(4): e0214872. Published online 2019 Apr 1. doi: 10.1371/journal.pone.0214872

PMCID:: PMC6443169

Abstract Article PDF–1.8M

Select item 634547613.

Clinical significance of cancer specific methylation of the CDO1 gene in small bowel cancer

Keita Kojima, Takatoshi Nakamura, Yosuke Ooizumi, Kazuharu Igarashi, Toshimichi Tanaka, Keigo Yokoi, Satoru Ishii, Nobuyuki Nishizawa, Hiroshi Katoh, Yoshimasa Kosaka, Takeo Sato, Masahiko Watanabe, Keishi Yamashita

PLoS One. 2019; 14(1): e0211108. Published online 2019 Jan 24. doi: 10.1371/journal.pone.0211108

PMCID:: PMC6345476

Abstract Article PDF–2.3M

Select item 619114114.

Methylated promoter DNA of CDO1 gene and preoperative serum CA19-9 are prognostic biomarkers in primary extrahepatic cholangiocarcinoma

Shuji Nakamoto, Yusuke Kumamoto, Kazuharu Igarashi, Yoshiki Fujiyama, Nobuyuki Nishizawa, Shigenori Ei, Hiroshi Tajima, Takashi Kaizu, Masahiko Watanabe, Keishi Yamashita

PLoS One. 2018; 13(10): e0205864. Published online 2018 Oct 16. doi: 10.1371/journal.pone.0205864

PMCID:: PMC6191141

Abstract Article PDF–1.3M

Select item 594498115.

Cysteine dioxygenase type 1 (CDO1) gene promoter methylation during the adenoma-carcinoma sequence in colorectal cancer

Keita Kojima, Takatoshi Nakamura, Makoto Ohbu, Hiroshi Katoh, Yosuke Ooizumi, Kazuharu Igarashi, Satoru Ishii, Toshimichi Tanaka, Keigo Yokoi, Nobuyuki Nishizawa, Kazuko Yokota, Yoshimasa Kosaka, Takeo Sato, Masahiko Watanabe, Keishi Yamashita

PLoS One. 2018; 13(5): e0194785. Published online 2018 May 10. doi: 10.1371/journal.pone.0194785

PMCID:: PMC5944981

Abstract Article PDF–12M

Select item 569780816.

Prognostic significance of promoter DNA hypermethylation of the cysteine dioxygenase 1 (CDO1) gene in primary gallbladder cancer and gallbladder disease

Kazuharu Igarashi, Keishi Yamashita, Hiroshi Katoh, Keita Kojima, Yosuke Ooizumi, Nobuyuki Nishizawa, Ryo Nishiyama, Hiroshi Kawamata, Hiroshi Tajima, Takashi Kaizu, Yusuke Kumamoto, Masahiko Watanabe

PLoS One. 2017; 12(11): e0188178. Published online 2017 Nov 21. doi: 10.1371/journal.pone.0188178

PMCID:: PMC5697808

Abstract Article PDF–4.0M

Select item 553161117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 519349318.

CDO1 promoter methylation is associated with gene silencing and is a prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients

Sebastian Meller, Lisa Zipfel, Heidrun Gevensleben, Jörn Dietrich, Jörg Ellinger, Michael Majores, Johannes Stein, Verena Sailer, Maria Jung, Glen Kristiansen, Dimo Dietrich

Epigenetics. 2016; 11(12): 871–880. Published online 2016 Sep 30. doi: 10.1080/15592294.2016.1241931

PMCID:: PMC5193493

Abstract Article PDF–570K

Select item 480585519.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Abstract Article PDF–4.6M

Select item 471868920.

Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer

Naoko Minatani, Mina Waraya, Keishi Yamashita, Mariko Kikuchi, Hideki Ushiku, Ken Kojo, Akira Ema, Hiroshi Nishimiya, Yoshimasa Kosaka, Hiroshi Katoh, Norihiko Sengoku, Hirokazu Tanino, David Sidransky, Masahiko Watanabe

PLoS One. 2016; 11(1): e0144862. Published online 2016 Jan 19. doi: 10.1371/journal.pone.0144862

PMCID:: PMC4718689

Abstract Article PDF–651K

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