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Items: 1 to 20 of 69

1.
Ketogenic diet induces p53-dependent cellular senescence in multiple organs
Sung-Jen Wei, Joseph R. Schell, E. Sandra Chocron, Mahboubeh Varmazyad, Guogang Xu, Wan Hsi Chen, Gloria M. Martinez, Felix F. Dong, Prethish Sreenivas, Rolando Trevino, Jr., Haiyan Jiang, Yan Du, Afaf Saliba, Wei Qian, Brandon Lorenzana, Alia Nazarullah, Jenny Chang, Kumar Sharma, Erin Munkácsy, Nobuo Horikoshi, David Gius
Sci Adv. 2024 May 17; 10(20): eado1463. Published online 2024 May 17. doi: 10.1126/sciadv.ado1463
PMCID:
PMC11100565
AbstractArticlePDF–11M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve
Camilla H. K. Hughes, Olivia E. Smith, Marie-Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy
Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2220849120. Published online 2023 Jul 26. doi: 10.1073/pnas.2220849120
PMCID:
PMC10410717
AbstractArticlePDF–3.9M
4.
PIDDosome-SCAP crosstalk controls high fructose diet dependent transition from simple steatosis to steatohepatitis
Ju Youn Kim, Lily Q. Wang, Valentina C. Sladky, Tae Gyu Oh, Junlai Liu, Kaitlyn Trinh, Felix Eichin, Michael Downes, Mojgan Hosseini, Etienne D. Jacotot, Ronald M. Evans, Andreas Villunger, Michael Karin
Cell Metab. Author manuscript; available in PMC 2023 Oct 4.
Published in final edited form as: Cell Metab. 2022 Oct 4; 34(10): 1548–1560.e6. Published online 2022 Aug 29. doi: 10.1016/j.cmet.2022.08.005
PMCID:
PMC9547947
AbstractArticlePDF–3.3M
5.
Caspase-2 modulates osteoclastogenesis through down-regulating oxidative stress
Danielle A. Callaway, Manuel A. Riquelme, Ramaswamy Sharma, Marisa Lopez-Cruzan, Brian A. Herman, Jean X. Jiang
Bone. Author manuscript; available in PMC 2022 Aug 18.
Published in final edited form as: Bone. 2015 Jul; 76: 40–48. Published online 2015 Mar 19. doi: 10.1016/j.bone.2015.03.006
Correction in:
Bone. 2016 Jun 10 : S8756-3282(16)30156-9.
PMCID:
PMC9387198
AbstractArticlePDF–1.8M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Death in the Balance: Alternative Participation of the Caspase-2 and -9 Pathways in Neuronal Death Induced by Nerve Growth Factor Deprivation
Carol M. Troy, Sylvia A. Rabacchi, Justin B. Hohl, James M. Angelastro, Lloyd A. Greene, Michael L. Shelanski
J Neurosci. 2001 Jul 15; 21(14): 5007–5016. doi: 10.1523/JNEUROSCI.21-14-05007.2001
Correction in:
J Neurosci. 2001 Aug 15; 21(16): np.
PMCID:
PMC6762825
AbstractArticlePDF–1.5M
8.
Upregulation of the Fas Receptor Death-Inducing Signaling Complex after Traumatic Brain Injury in Mice and Humans
Jianhua Qiu, Michael J. Whalen, Pedro Lowenstein, Gary Fiskum, Brenda Fahy, Ribal Darwish, Bizhan Aarabi, Junying Yuan, Michael A. Moskowitz
J Neurosci. 2002 May 1; 22(9): 3504–3511. doi: 10.1523/JNEUROSCI.22-09-03504.2002
PMCID:
PMC6758354
AbstractArticlePDF–445K
9.
Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling
Zhi-Xiang Xu, Ji-Wei Tan, Haifei Xu, Cassandra J. Hill, Olga Ostrovskaya, Kirill A. Martemyanov, Baoji Xu
Nat Commun. 2019; 10: 3622. Published online 2019 Aug 9. doi: 10.1038/s41467-019-11575-1
PMCID:
PMC6689033
AbstractArticlePDF–2.5M
10.
Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling
Loretta Dorstyn, Emily Hackett-Jones, Andrej Nikolic, Murray D. Norris, Yoon Lim, John Toubia, Michelle Haber, Sharad Kumar
Cell Death Dis. 2019 Feb; 10(2): 56. Published online 2019 Jan 22. doi: 10.1038/s41419-018-1296-0
PMCID:
PMC6343006
AbstractArticlePDF–3.1M
11.
ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
Ju Youn Kim, Ricard Garcia-Carbonell, Shinichiro Yamachika, Peng Zhao, Debanjan Dhar, Rohit Loomba, Randal J Kaufman, Alan R Saltiel, Michael Karin
Cell. Author manuscript; available in PMC 2019 Sep 20.
Published in final edited form as: Cell. 2018 Sep 20; 175(1): 133–145.e15. Published online 2018 Sep 13. doi: 10.1016/j.cell.2018.08.020
PMCID:
PMC6159928
AbstractArticlePDF–1.5M
12.
NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus
Kiyohiro Ando, Melissa J. Parsons, Richa B. Shah, Chloé I. Charendoff, Sheré L. Paris, Peter H. Liu, Sara R. Fassio, Brittany A. Rohrman, Ruth Thompson, Andrew Oberst, Samuel Sidi, Lisa Bouchier-Hayes
J Cell Biol. 2017 Jun 5; 216(6): 1795–1810. doi: 10.1083/jcb.201608095
PMCID:
PMC5461015
AbstractArticlePDF–2.8M
13.
Caspase-2-mediated cell death is required for deleting aneuploid cells
S Dawar, Y Lim, J Puccini, M White, P Thomas, L Bouchier-Hayes, D R Green, L Dorstyn, S Kumar
Oncogene. 2017 May 11; 36(19): 2704–2714. Published online 2016 Dec 19. doi: 10.1038/onc.2016.423
PMCID:
PMC5442422
AbstractArticlePDF–1.4M
14.
Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease
M V Machado, G A Michelotti, M L Jewell, T A Pereira, G Xie, R T Premont, A M Diehl
Cell Death Dis. 2016 Feb; 7(2): e2096. Published online 2016 Feb 18. doi: 10.1038/cddis.2016.19
PMCID:
PMC5399190
AbstractArticlePDF–5.2M
15.
BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein
Juan Liu, Hailong Wang, Jinyan Gu, Tingjuan Deng, Zhuangchuan Yuan, Boli Hu, Yunbin Xu, Yan Yan, Jie Zan, Min Liao, Erin DiCaprio, Jianrong Li, Shuo Su, Jiyong Zhou
Autophagy. 2017; 13(4): 739–753. Published online 2017 Jan 27. doi: 10.1080/15548627.2017.1280220
PMCID:
PMC5388250
AbstractArticlePDF–1.8M
16.
Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice
Swati Dawar, Nur Hezrin Shahrin, Nikolina Sladojevic, Richard J D'Andrea, Loretta Dorstyn, Devendra K Hiwase, Sharad Kumar
Cell Death Dis. 2016 Dec; 7(12): e2509. Published online 2016 Dec 1. doi: 10.1038/cddis.2016.406
PMCID:
PMC5260989
AbstractArticlePDF–1.3M
17.
Caspase-2 deficiency accelerates chemically induced liver cancer in mice
S Shalini, A Nikolic, C H Wilson, J Puccini, N Sladojevic, J Finnie, L Dorstyn, S Kumar
Cell Death Differ. 2016 Oct; 23(10): 1727–1736. Published online 2016 Aug 12. doi: 10.1038/cdd.2016.81
PMCID:
PMC5041200
AbstractArticlePDF–2.3M
18.
Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice
Melissa Braga, Amiya P. Sinha Hikim, Sanjit Datta, Monica G. Ferrini, Danielle Brown, Ekaterina L. Kovacheva, Nestor F. Gonzalez-Cadavid, Indrani Sinha-Hikim
Apoptosis. Author manuscript; available in PMC 2016 Jan 29.
Published in final edited form as: Apoptosis. 2008 Jun; 13(6): 822–832. doi: 10.1007/s10495-008-0216-7
PMCID:
PMC4732709
AbstractArticlePDF–813K
19.
Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice
C H Wilson, S Shalini, A Filipovska, T R Richman, S Davies, S D Martin, S L McGee, J Puccini, A Nikolic, L Dorstyn, S Kumar
Cell Death Dis. 2015 Jan; 6(1): e1597. Published online 2015 Jan 22. doi: 10.1038/cddis.2014.567
PMCID:
PMC4669765
AbstractArticlePDF–1.7M
20.
The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd
L Peintner, L Dorstyn, S Kumar, T Aneichyk, A Villunger, C Manzl
Cell Death Differ. 2015 Nov; 22(11): 1803–1811. Published online 2015 Apr 10. doi: 10.1038/cdd.2015.31
PMCID:
PMC4648327
AbstractArticlePDF–1.8M

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