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Select item 114632711.

Bidirectional regulation of motor circuits using magnetogenetic gene therapy

Santiago R. Unda, Lisa E. Pomeranz, Roberta Marongiu, Xiaofei Yu, Leah Kelly, Gholamreza Hassanzadeh, Henrik Molina, George Vaisey, Putianqi Wang, Jonathan P. Dyke, Edward K. Fung, Logan Grosenick, Rick Zirkel, Aldana M. Antoniazzi, Sofya Norman, Conor M. Liston, Chris Schaffer, Nozomi Nishimura, Sarah A. Stanley, Jeffrey M. Friedman, Michael G. Kaplitt

Sci Adv. 2024 Oct 11; 10(41): eadp9150. Published online 2024 Oct 9. doi: 10.1126/sciadv.adp9150

PMCID:: PMC11463271

Abstract Article PDF–12M

Select item 113029172.

Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation

Fan Shao, An-Vi Phan, Wenjie Yu, Yuwei Guo, Jamie Thompson, Carter Coppinger, Shankar R. Venugopalan, Brad A. Amendt, Eric Van Otterloo, Huojun Cao

PLoS Genet. 2024 Jul; 20(7): e1011364. Published online 2024 Jul 25. doi: 10.1371/journal.pgen.1011364

PMCID:: PMC11302917

Abstract Article PDF–9.1M

Select item 111782133.

Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle stem cells

Mao Kuriki, Amaury Korb, Glenda Comai, Shahragim Tajbakhsh

PLoS Genet. 2024 Jun; 20(6): e1010935. Published online 2024 Jun 14. doi: 10.1371/journal.pgen.1010935

PMCID:: PMC11178213

Abstract Article PDF–6.0M

Select item 111419334.

Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2

Yizheng Jiang, Yu Peng, Qi Tian, Zhe Cheng, Bei Feng, Junping Hu, Lu Xia, Hui Guo, Kun Xia, Liang Zhou, Zhengmao Hu

JCI Insight. 2024 May 8; 9(9): e177032. Published online 2024 Apr 9. doi: 10.1172/jci.insight.177032

PMCID:: PMC11141933

Abstract Article PDF–2.4M

Select item 109811585.

Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity

Seungwoon Seo, Seong Keun Sonn, Hyae Yon Kweon, Jing Jin, Tsutomu Kume, Je Yeong Ko, Jong Hoon Park, Goo Taeg Oh

Invest Ophthalmol Vis Sci. 2024 Mar; 65(3): 30. Published online 2024 Mar 22. doi: 10.1167/iovs.65.3.30

PMCID:: PMC10981158

Abstract Article PDF–20M

Select item 109262046.

Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

Mary E. Mohr, Shuang Li, Allison M. Trouten, Rebecca A. Stairley, Patrick L. Roddy, Chun Liu, Min Zhang, Henry M. Sucov, Ge Tao

iScience. 2024 Mar 15; 27(3): 109219. Published online 2024 Feb 15. doi: 10.1016/j.isci.2024.109219

PMCID:: PMC10926204

Abstract Article PDF–13M

Select item 109176607.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108842408.

Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects

Sabrina Quilez, Emilie Dumontier, Christopher Baim, Joseph Kam, Jean-François Cloutier

Front Cell Dev Biol. 2024; 12: 1256465. Published online 2024 Feb 9. doi: 10.3389/fcell.2024.1256465

PMCID:: PMC10884240

Abstract Article PDF–6.8M

Select item 108534539.

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi

Hong-Nhung Tran, Quy-Hoai Nguyen, Yongsu Jeong

Front Cell Dev Biol. 2024; 12: 1336308. Published online 2024 Jan 26. doi: 10.3389/fcell.2024.1336308

PMCID:: PMC10853453

Abstract Article PDF–8.4M

Select item 1065835610.

The transcription regulator Lmo3 is required for the development of medial ganglionic eminence derived neurons in the external globus pallidus

Shiona Biswas, C. Savio Chan, John L.R. Rubenstein, Lin Gan

Dev Biol. Author manuscript; available in PMC 2024 Nov 1.

Published in final edited form as: Dev Biol. 2023 Nov; 503: 10–24. Published online 2023 Aug 1. doi: 10.1016/j.ydbio.2023.07.007

PMCID:: PMC10658356

Abstract Article PDF–4.3M

Select item 1065623411.

Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development

Dan Su, Steve Eliason, Zhao Sun, Fan Shao, Brad A. Amendt

J Biol Chem. 2023 Nov; 299(11): 105324. Published online 2023 Oct 6. doi: 10.1016/j.jbc.2023.105324

PMCID:: PMC10656234

Abstract Article PDF–5.0M

Select item 1050639712.

Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages

Megan Rowton, Carlos Perez-Cervantes, Suzy Hur, Jessica Jacobs-Li, Emery Lu, Nikita Deng, Alexander Guzzetta, Andrew D. Hoffmann, Matthew Stocker, Jeffrey D. Steimle, Sonja Lazarevic, Sophie Oubaha, Xinan H. Yang, Chul Kim, Shuhan Yu, Heather Eckart, Mervenaz Koska, Erika Hanson, Sunny S.K. Chan, Daniel J. Garry, Michael Kyba, Anindita Basu, Kohta Ikegami, Sebastian Pott, Ivan P. Moskowitz

Dev Cell. Author manuscript; available in PMC 2023 Sep 18.

Published in final edited form as: Dev Cell. 2022 Sep 26; 57(18): 2181–2203.e9. Published online 2022 Sep 14. doi: 10.1016/j.devcel.2022.08.009

PMCID:: PMC10506397

Abstract Article PDF–3.7M

Select item 1026668113.

Overlapping functions of SIX homeoproteins during embryonic myogenesis

Maud Wurmser, Rouba Madani, Nathalie Chaverot, Stéphanie Backer, Matthew Borok, Matthieu Dos Santos, Glenda Comai, Shahragim Tajbakhsh, Frédéric Relaix, Marc Santolini, Ramkumar Sambasivan, Rulang Jiang, Pascal Maire

PLoS Genet. 2023 Jun; 19(6): e1010781. Published online 2023 Jun 2. doi: 10.1371/journal.pgen.1010781

PMCID:: PMC10266681

Abstract Article PDF–4.6M

Select item 1024753314.

Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm

Marissa L. Gredler, Jennifer A. Zallen

Dev Cell. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Dev Cell. 2023 Jun 5; 58(11): 933–950.e5. Published online 2023 Apr 19. doi: 10.1016/j.devcel.2023.03.018

PMCID:: PMC10247533

Abstract Article PDF–2.3M

Select item 1016683615.

A genetic and developmental biological approach for a family with complex congenital heart diseases—evidence of digenic inheritance

Yu Yoshida, Keiko Uchida, Kazuki Kodo, Reina Ishizaki-Asami, Jun Maeda, Yoshinori Katsumata, Shinsuke Yuasa, Keiichi Fukuda, Kenjiro Kosaki, Yusuke Watanabe, Osamu Nakagawa, Hiroyuki Yamagishi

Front Cardiovasc Med. 2023; 10: 1135141. Published online 2023 Apr 25. doi: 10.3389/fcvm.2023.1135141

PMCID:: PMC10166836

Abstract Article PDF–18M

Select item 1011912116.

Topologically associating domain boundaries are required for normal genome function

Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio

Commun Biol. 2023; 6: 435. Published online 2023 Apr 20. doi: 10.1038/s42003-023-04819-w