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Items: 1 to 20 of 21

1.
BACE2 suppression promotes β-cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression
Gema Alcarraz-Vizán, Carlos Castaño, Montse Visa, Joel Montane, Joan-Marc Servitja, Anna Novials
Cell Mol Life Sci. 2017 Aug; 74(15): 2827–2838. Published online 2017 Mar 23. doi: 10.1007/s00018-017-2505-1
PMCID:
PMC11107557
AbstractArticlePDF–3.0M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
BACE2 deficiency impairs expression and function of endothelial nitric oxide synthase in brain endothelial cells
Tongrong He, Livius V. d’Uscio, Zvonimir S. Katusic
J Neurochem. Author manuscript; available in PMC 2023 Oct 25.
Published in final edited form as: J Neurochem. 2023 Sep; 166(6): 928–942. Published online 2023 Aug 7. doi: 10.1111/jnc.15929
PMCID:
PMC10599353
AbstractArticlePDF–1.2M
4.
BACE2 suppression in mice aggravates the adverse metabolic consequences of an obesogenic diet
Daniela Díaz-Catalán, Gema Alcarraz-Vizán, Carlos Castaño, Sara de Pablo, Júlia Rodríguez-Comas, Antonio Fernández-Pérez, Mario Vallejo, Sara Ramírez, Marc Claret, Marcelina Parrizas, Anna Novials, Joan-Marc Servitja
Mol Metab. 2021 Nov; 53: 101251. Published online 2021 May 17. doi: 10.1016/j.molmet.2021.101251
PMCID:
PMC8190493
AbstractArticlePDF–2.0M
5.
Defining the lineage of thermogenic perivascular adipose tissue
Anthony R. Angueira, Alexander P. Sakers, Corey D. Holman, Lan Cheng, Michelangella N. Arbocco, Farnaz Shamsi, Matthew D. Lynes, Rojesh Shrestha, Chihiro Okada, Kirill Batmanov, Katalin Susztak, Yu-Hua Tseng, Lucy Liaw, Patrick Seale
Nat Metab. Author manuscript; available in PMC 2021 Oct 12.
Published in final edited form as: Nat Metab. 2021 Apr; 3(4): 469–484. Published online 2021 Apr 12. doi: 10.1038/s42255-021-00380-0
PMCID:
PMC8136151
AbstractArticlePDF–6.2M
6.
Proteolytic Processing of Neuregulin 2
Maria Czarnek, Joanna Bereta
Mol Neurobiol. 2020; 57(4): 1799–1813. Published online 2019 Dec 14. doi: 10.1007/s12035-019-01846-9
PMCID:
PMC7118043
AbstractArticlePDF–3.9M
7.
BACE2 distribution in major brain cell types and identification of novel substrates
Iryna Voytyuk, Stephan A Mueller, Julia Herber, An Snellinx, Dieder Moechars, Geert van Loo, Stefan F Lichtenthaler, Bart De Strooper
Life Sci Alliance. 2018 Jan; 1(1): e201800026. Published online 2018 Feb 15. doi: 10.26508/lsa.201800026
PMCID:
PMC6238391
AbstractArticlePDF–4.4M
8.
BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells
Leila Rochin, Ilse Hurbain, Lutgarde Serneels, Cecile Fort, Brenda Watt, Pascal Leblanc, Michael S. Marks, Bart De Strooper, Graça Raposo, Guillaume van Niel
Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10658–10663. Published online 2013 Jun 10. doi: 10.1073/pnas.1220748110
PMCID:
PMC3696817
AbstractArticlePDF–1018K
9.
Systematic Proteomic Analysis Identifies β-Site Amyloid Precursor Protein Cleaving Enzyme 2 and 1 (BACE2 and BACE1) Substrates in Pancreatic β-Cells
Ina Stützer, Nathalie Selevsek, Daria Esterházy, Alexander Schmidt, Ruedi Aebersold, Markus Stoffel
J Biol Chem. 2013 Apr 12; 288(15): 10536–10547. Published online 2013 Feb 19. doi: 10.1074/jbc.M112.444703
PMCID:
PMC3624435
AbstractArticlePDF–2.0M
10.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
11.
β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment
Jun Cai, Xiaoping Qi, Norbert Kociok, Sergej Skosyrski, Alonso Emilio, Qing Ruan, Song Han, Li Liu, Zhijuan Chen, Catherine Bowes Rickman, Todd Golde, Maria B Grant, Paul Saftig, Lutgarde Serneels, Bart de Strooper, Antonia M Joussen, Michael E Boulton
EMBO Mol Med. 2012 Sep; 4(9): 980–991. Published online 2012 Aug 20. doi: 10.1002/emmm.201101084
PMCID:
PMC3491829
AbstractArticlePDF–1.7M
12.
Identification of Novel Markers of Mouse Fetal Ovary Development
Huijun Chen, James S. Palmer, Rathi D. Thiagarajan, Marcel E. Dinger, Emmanuelle Lesieur, Hansheng Chiu, Alexandra Schulz, Cassy Spiller, Sean M. Grimmond, Melissa H. Little, Peter Koopman, Dagmar Wilhelm
PLoS One. 2012; 7(7): e41683. Published online 2012 Jul 26. doi: 10.1371/journal.pone.0041683
PMCID:
PMC3406020
AbstractArticlePDF–6.0M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
β-secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins
Carlo Sala Frigerio, Julia V. Fadeeva, Aedín M. Minogue, Martin Citron, Fred Van Leuven, Matthias Stufenbiel, Paolo Paganetti, Dennis J. Selkoe, Dominic M. Walsh
FEBS J. Author manuscript; available in PMC 2011 Mar 1.
Published in final edited form as: FEBS J. 2010 Mar; 277(6): 1503–1518. Published online 2010 Feb 15. doi: 10.1111/j.1742-4658.2010.07579.x
PMCID:
PMC2847843
AbstractArticlePDF–1.0M
15.
Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution
Eric W. Brunskill, Bruce J. Aronow, Kylie Georgas, Bree Rumballe, M. Todd Valerius, Jeremy Aronow, Vivek Kaimal, Anil G. Jegga, Sean Grimmond, Andrew P. McMahon, Larry T. Patterson, Melissa H. Little, S. Steven Potter
Dev Cell. Author manuscript; available in PMC 2009 Nov 1.
Published in final edited form as: Dev Cell. 2008 Nov; 15(5): 781–791. doi: 10.1016/j.devcel.2008.09.007
Correction in:
volume 16 on page 482
PMCID:
PMC2653061
AbstractArticlePDF–4.9M
16.
Identification of transcripts with enriched expression in the developing and adult pancreas
Brad G Hoffman, Bogard Zavaglia, Joy Witzsche, Teresa Ruiz de Algara, Mike Beach, Pamela A Hoodless, Steven JM Jones, Marco A Marra, Cheryl D Helgason
Genome Biol. 2008; 9(6): R99. Published online 2008 Jun 14. doi: 10.1186/gb-2008-9-6-r99
PMCID:
PMC2481431
AbstractArticlePDF–2.2M
17.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
18.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
19.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
20.
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Axel Visel, Christina Thaller, Gregor Eichele
Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029
PMCID:
PMC308763
AbstractArticlePDF–253K

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