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Items: 1 to 20 of 61

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4CreERT2 versus AggrecanCreERT2 transgene in mice
Qing Yao, Weiyuan Gong, Xiaohao Wu, Donghao Gan, Chu Tao, Sixiong Lin, Minghao Qu, Zhongtian Ouyang, Mingjue Chen, Xinjia Hu, Guozhi Xiao
J Orthop Translat. 2023 Jul; 41: 12–19. Published online 2023 May 31. doi: 10.1016/j.jot.2023.05.005
PMCID:
PMC10244901
AbstractArticlePDF–3.2M
3.
Digits in a dish: An in vitro system to assess the molecular genetics of hand/foot development at single-cell resolution
Allison M. Fuiten, Yuki Yoshimoto, Chisa Shukunami, H. Scott Stadler
Front Cell Dev Biol. 2023; 11: 1135025. Published online 2023 Mar 13. doi: 10.3389/fcell.2023.1135025
PMCID:
PMC10040768
AbstractArticlePDF–5.3M
4.
Creb5 coordinates synovial joint formation with the genesis of articular cartilage
Cheng-Hai Zhang, Yao Gao, Han-Hwa Hung, Zhu Zhuo, Alan J. Grodzinsky, Andrew B. Lassar
Nat Commun. 2022; 13: 7295. Published online 2022 Nov 26. doi: 10.1038/s41467-022-35010-0
PMCID:
PMC9701237
AbstractArticlePDF–10M
5.
Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development
Kosei Nagata, Hironori Hojo, Song Ho Chang, Hiroyuki Okada, Fumiko Yano, Ryota Chijimatsu, Yasunori Omata, Daisuke Mori, Yuma Makii, Manabu Kawata, Taizo Kaneko, Yasuhide Iwanaga, Hideki Nakamoto, Yuji Maenohara, Naohiro Tachibana, Hisatoshi Ishikura, Junya Higuchi, Yuki Taniguchi, Shinsuke Ohba, Ung-il Chung, Sakae Tanaka, Taku Saito
Nat Commun. 2022; 13: 6187. Published online 2022 Oct 19. doi: 10.1038/s41467-022-33744-5
PMCID:
PMC9581901
AbstractArticlePDF–3.2M
6.
RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and suppresses ectopic ossification
Naohiro Tachibana, Ryota Chijimatsu, Hiroyuki Okada, Takeshi Oichi, Yuki Taniguchi, Yuji Maenohara, Junya Miyahara, Hisatoshi Ishikura, Yasuhide Iwanaga, Yusuke Arino, Kosei Nagata, Hideki Nakamoto, So Kato, Toru Doi, Yoshitaka Matsubayashi, Yasushi Oshima, Asuka Terashima, Yasunori Omata, Fumiko Yano, Shingo Maeda, Shiro Ikegawa, Masahide Seki, Yutaka Suzuki, Sakae Tanaka, Taku Saito
Sci Adv. 2022 Aug; 8(33): eabn2138. Published online 2022 Aug 19. doi: 10.1126/sciadv.abn2138
PMCID:
PMC9390986
AbstractArticlePDF–14M
7.
Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs
Minwook Kim, Eiki Koyama, Cheri M. Saunders, William Querido, Nancy Pleshko, Maurizio Pacifici
Biol Open. 2022 Jun 15; 11(6): bio059381. Published online 2022 Jun 15. doi: 10.1242/bio.059381
PMCID:
PMC9212078
AbstractArticlePDF–16M
8.
Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis
Yoshifumi Takahata, Hiromasa Hagino, Ayaka Kimura, Mitsuki Urushizaki, Shiori Yamamoto, Kanta Wakamori, Tomohiko Murakami, Kenji Hata, Riko Nishimura
Int J Mol Sci. 2022 May; 23(9): 4672. Published online 2022 Apr 23. doi: 10.3390/ijms23094672
PMCID:
PMC9105027
AbstractArticlePDF–1.6M
9.
Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice
Daniel S. Yang, Edward E. Dickerson, Ling X. Zhang, Holly Richendrfer, Padmini N. Karamchedu, Gary J. Badger, Tannin A. Schmidt, Alger M. Fredericks, Khaled A. Elsaid, Gregory D. Jay
Int J Mol Sci. 2022 Apr; 23(8): 4245. Published online 2022 Apr 12. doi: 10.3390/ijms23084245
PMCID:
PMC9025840
AbstractArticlePDF–2.7M
10.
Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration
Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid
Arthritis Res Ther. 2021; 23: 241. Published online 2021 Sep 14. doi: 10.1186/s13075-021-02621-9
Correction in:
Arthritis Res Ther. 2021; 23: 276.
PMCID:
PMC8439011
AbstractArticlePDF–2.8M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
PRMT5 is necessary to form distinct cartilage identities in the knee and long bone
Janani Ramachandran, Zhaoyang Liu, Ryan S. Gray, Steven A. Vokes
Dev Biol. Author manuscript; available in PMC 2020 Dec 15.
Published in final edited form as: Dev Biol. 2019 Dec 15; 456(2): 154–163. Published online 2019 Aug 20. doi: 10.1016/j.ydbio.2019.08.012
PMCID:
PMC6884688
AbstractArticlePDF–3.4M
13.
Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone
Fengjun Xuan, Fumiko Yano, Daisuke Mori, Ryota Chijimatsu, Yuji Maenohara, Hideki Nakamoto, Yoshifumi Mori, Yuma Makii, Takeshi Oichi, Makoto Mark Taketo, Hironori Hojo, Shinsuke Ohba, Ung-il Chung, Sakae Tanaka, Taku Saito
Arthritis Res Ther. 2019; 21: 247. Published online 2019 Nov 27. doi: 10.1186/s13075-019-2041-5
PMCID:
PMC6880374
AbstractArticlePDF–2.3M
14.
Novel Role for Claudin-11 in the Regulation of Osteoblasts via Modulation of ADAM10-mediated Notch Signaling
Richard C. Lindsey, Weirong Xing, Sheila Pourteymoor, Catrina Godwin, Alexander Gow, Subburaman Mohan
J Bone Miner Res. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: J Bone Miner Res. 2019 Oct; 34(10): 1910–1922. Published online 2019 Jul 26. doi: 10.1002/jbmr.3763
PMCID:
PMC6813858
AbstractArticlePDF–2.7M
15.
Combinatorial Prg4 and Il-1ra Gene Therapy Protects Against Hyperalgesia and Cartilage Degeneration in Post-Traumatic Osteoarthritis
Adrianne Stone, Matthew W. Grol, Merry Z. C. Ruan, Brian Dawson, Yuqing Chen, Ming-Ming Jiang, I-wen Song, Prathap Jayaram, Racel Cela, Francis Gannon, Brendan H. L. Lee
Hum Gene Ther. 2019 Feb 1; 30(2): 225–235. Published online 2019 Feb 8. doi: 10.1089/hum.2018.106
PMCID:
PMC6383580
AbstractArticlePDF–778K
16.
BMP9 stimulates joint regeneration at digit amputation wounds in mice
Ling Yu, Lindsay A. Dawson, Mingquan Yan, Katherine Zimmel, Yu-Lieh Lin, Connor P. Dolan, Manjong Han, Ken Muneoka
Nat Commun. 2019; 10: 424. Published online 2019 Feb 5. doi: 10.1038/s41467-018-08278-4
PMCID:
PMC6363752
AbstractArticlePDF–16M
17.
Prg4 prevents osteoarthritis induced by dominant-negative interference of TGF-ß signaling in mice
Robert Dalton Chavez, Philip Sohn, Rosa Serra
PLoS One. 2019; 14(1): e0210601. Published online 2019 Jan 10. doi: 10.1371/journal.pone.0210601
PMCID:
PMC6328116
AbstractArticlePDF–3.2M
18.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
19.
FoxO transcription factors influence cartilage maturation, homeostasis and osteoarthritis pathogenesis by modulating autophagy and proteoglycan 4
Tokio Matsuzaki, Oscar Alvarez-Garcia, Sho Mokuda, Keita Nagira, Merissa Olmer, Ramya Gamini, Kohei Miyata, Yukio Akasaki, Andrew I. Su, Hiroshi Asahara, Martin K. Lotz
Sci Transl Med. Author manuscript; available in PMC 2019 Feb 14.
Published in final edited form as: Sci Transl Med. 2018 Feb 14; 10(428): eaan0746. doi: 10.1126/scitranslmed.aan0746
PMCID:
PMC6204214
AbstractArticlePDF–1.2M
20.
cAMP attenuates TGF-β’s profibrotic responses in osteoarthritic synoviocytes: involvement of hyaluronan and PRG4
Marwa M. Qadri, Gregory D. Jay, Rennolds S. Ostrom, Ling X. Zhang, Khaled A. Elsaid
Am J Physiol Cell Physiol. 2018 Sep 1; 315(3): C432–C443. Published online 2018 Jun 13. doi: 10.1152/ajpcell.00041.2018
PMCID:
PMC6171038
AbstractArticle

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