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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693502.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 104960863.

Inhibition of the dorsomedial striatal direct pathway is essential for the execution of action sequences

Anna Kono, Yu Shikano, Kenji F. Tanaka, Katsunori Yamaura, Iku Tsutsui‐Kimura

Neuropsychopharmacol Rep. 2023 Sep; 43(3): 414–424. Published online 2023 Aug 8. doi: 10.1002/npr2.12369

PMCID:: PMC10496086

Abstract Article PDF–2.6M

Select item 98904764.

Role of PDE10A in vascular smooth muscle cell hyperplasia and pathological vascular remodelling

Lingfeng Luo, Yujun Cai, Yishuai Zhang, Chia G Hsu, Vyacheslav A Korshunov, Xiaochun Long, Peter A Knight, Bradford C Berk, Chen Yan

Cardiovasc Res. 2022 Aug; 118(12): 2703–2717. Published online 2021 Sep 22. doi: 10.1093/cvr/cvab304

Correction in:: Cardiovasc Res. 2023 Mar; 119(3): 879.

PMCID:: PMC9890476

Abstract Article PDF–2.0M

Select item 96658855.

Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures

Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang

Neuron. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028

PMCID:: PMC9665885

Abstract Article PDF–4.5M

Select item 89583646.

DNA methylation in the pathophysiology of hyperphenylalaninemia in the PAH^enu2 mouse model of phenylketonuria

S.F. Dobrowolski, J. Lyons-Weiler, K. Spridik, J. Vockley, K. Skvorak, A. Biery

Mol Genet Metab. Author manuscript; available in PMC 2022 Mar 28.

Published in final edited form as: Mol Genet Metab. 2016 Sep; 119(1-2): 1–7. Published online 2016 Jan 14. doi: 10.1016/j.ymgme.2016.01.001

PMCID:: PMC8958364

Abstract Article PDF–346K

Select item 86648997.

Phosphodiesterase 10A is a key mediator of lung inflammation

Chia George Hsu, Fabeha Fazal, Arshad Rahman, Bradford C. Berk, Chen Yan

J Immunol. Author manuscript; available in PMC 2022 Jun 15.

Published in final edited form as: J Immunol. 2021 Jun 15; 206(12): 3010–3020. Published online 2021 Jun 11. doi: 10.4049/jimmunol.2001026

PMCID:: PMC8664899

Abstract Article PDF–2.5M

Select item 83132398.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 714798610.

A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction

Si Chen, Yishuai Zhang, Janet K. Lighthouse, Deanne M. Mickelsen, Jiangbin Wu, Peng Yao, Eric M. Small, Chen Yan

Circulation. Author manuscript; available in PMC 2021 Jan 21.

Published in final edited form as: Circulation. 2020 Jan 21; 141(3): 217–233. Published online 2019 Dec 5. doi: 10.1161/CIRCULATIONAHA.119.042178

PMCID:: PMC7147986

Abstract Article PDF–3.8M

Select item 676408911.

SynGO: an evidence-based, expert-curated knowledgebase for the synapse

Frank Koopmans, Pim van Nierop, Maria Andres-Alonso, Andrea Byrnes, Tony Cijsouw, Marcelo P. Coba, L. Niels Cornelisse, Ryan J. Farrell, Hana L. Goldschmidt, Daniel P. Howrigan, Natasha K. Hussain, Cordelia Imig, Arthur P.H. de Jong, Hwajin Jung, Mahdokht Kohansalnodehi, Barbara Kramarz, Noa Lipstein, Ruth C. Lovering, Harold MacGillavry, Vittoria Mariano, Huaiyu Mi, Momchil Ninov, David Osumi-Sutherland, Rainer Pielot, Karl-Heinz Smalla, Haiming Tang, Katherine Tashman, Ruud F.G. Toonen, Chiara Verpelli, Rita Reig-Viader, Kyoko Watanabe, Jan van Weering, Tilmann Achsel, Ghazaleh Ashrafi, Nimra Asi, Tyler C. Brown, Pietro De Camilli, Marc Feuermann, Rebecca E. Foulger, Pascale Gaudet, Anoushka Joglekar, Alexandros Kanellopoulos, Robert Malenka, Roger A. Nicoll, Camila Pulido, Jaime de Juan-Sanz, Morgan Sheng, Thomas C. Südhof, Hagen U. Tilgner, Claudia Bagni, Àlex Bayés, Thomas Biederer, Nils Brose, John Jia En Chua, Daniela C. Dieterich, Eckart D. Gundelfinger, Casper Hoogenraad, Richard L. Huganir, Reinhard Jahn, Pascal S. Kaeser, Eunjoon Kim, Michael R. Kreutz, Peter S. McPherson, Ben M. Neale, Vincent O’Connor, Danielle Posthuma, Timothy A. Ryan, Carlo Sala, Guoping Feng, Steven E. Hyman, Paul D. Thomas, August B. Smit, Matthijs Verhage

Neuron. Author manuscript; available in PMC 2020 Jul 17.

Published in final edited form as: Neuron. 2019 Jul 17; 103(2): 217–234.e4. Published online 2019 Jun 3. doi: 10.1016/j.neuron.2019.05.002

PMCID:: PMC6764089

Abstract Article PDF–1.6M

Select item 670569012.

Phosphodiesterase-10A Inverse Changes in Striatopallidal and Striatoentopeduncular Pathways of a Transgenic Mouse Model of DYT1 Dystonia

Vincenza D'Angelo, Valentina Castelli, Mauro Giorgi, Silvia Cardarelli, Ilaria Saverioni, Francesca Palumbo, Paola Bonsi, Antonio Pisani, Carmela Giampà, Roberto Sorge, Stefano Biagioni, Francesca R. Fusco, Giuseppe Sancesario

J Neurosci. 2017 Feb 22; 37(8): 2112–2124. doi: 10.1523/JNEUROSCI.3207-15.2016

PMCID:: PMC6705690

Abstract Article PDF–3.2M

Select item 667221913.

Striatal Medium Spiny Neurons Terminate in a Distinct Region in the Lateral Hypothalamic Area and Do Not Directly Innervate Orexin/Hypocretin- or Melanin-Concentrating Hormone-Containing Neurons

Hiromi Sano, Mineto Yokoi

J Neurosci. 2007 Jun 27; 27(26): 6948–6955. doi: 10.1523/JNEUROSCI.0514-07.2007

PMCID:: PMC6672219

Abstract Article PDF–383K

Select item 663248514.

Interplay of Palmitoylation and Phosphorylation in the Trafficking and Localization of Phosphodiesterase 10A: Implications for the Treatment of Schizophrenia

Erik I. Charych, Li-Xin Jiang, Frederick Lo, Kelly Sullivan, Nicholas J. Brandon

J Neurosci. 2010 Jul 7; 30(27): 9027–9037. doi: 10.1523/JNEUROSCI.1635-10.2010

PMCID:: PMC6632485

Abstract Article PDF–1.9M

Select item 659663715.

Ventrolateral Striatal Medium Spiny Neurons Positively Regulate Food-Incentive, Goal-Directed Behavior Independently of D1 and D2 Selectivity

Akiyo Natsubori, Iku Tsutsui-Kimura, Hiroshi Nishida, Youcef Bouchekioua, Hiroshi Sekiya, Motokazu Uchigashima, Masahiko Watanabe, Alban de Kerchove d'Exaerde, Masaru Mimura, Norio Takata, Kenji F. Tanaka

J Neurosci. 2017 Mar 8; 37(10): 2723–2733. doi: 10.1523/JNEUROSCI.3377-16.2017

PMCID:: PMC6596637

Abstract Article PDF–3.7M

Select item 642046316.

Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer

Arancha Botella-López, Raquel Garcia-Lopez, Ana Pombero, Salvador Martinez

Brain Struct Funct. 2019; 224(2): 661–679. Published online 2018 Nov 23. doi: 10.1007/s00429-018-1794-y

PMCID:: PMC6420463

Abstract Article PDF–11M

Select item 631390017.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 546738918.

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction

Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum, II

Neural Plast. 2017; 2017: 4153076. Published online 2017 May 28. doi: 10.1155/2017/4153076

PMCID:: PMC5467389

Abstract Article PDF–3.2M

Select item 483343619.

Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy

Christine P. Diggle, Stacey J. Sukoff Rizzo, Michael Popiolek, Reetta Hinttala, Jan-Philip Schülke, Manju A. Kurian, Ian M. Carr, Alexander F. Markham, David T. Bonthron, Christopher Watson, Saghira Malik Sharif, Veronica Reinhart, Larry C. James, Michelle A. Vanase-Frawley, Erik Charych, Melanie Allen, John Harms, Christopher J. Schmidt, Joanne Ng, Karen Pysden, Christine Strick, Päivi Vieira, Katariina Mankinen, Hannaleena Kokkonen, Matti Kallioinen, Raija Sormunen, Juha O. Rinne, Jarkko Johansson, Kati Alakurtti, Laura Huilaja, Tiina Hurskainen, Kaisa Tasanen, Eija Anttila, Tiago Reis Marques, Oliver Howes, Marius Politis, Somayyeh Fahiminiya, Khanh Q. Nguyen, Jacek Majewski, Johanna Uusimaa, Eamonn Sheridan, Nicholas J. Brandon

Am J Hum Genet. 2016 Apr 7; 98(4): 735–743. Published online 2016 Apr 7. doi: 10.1016/j.ajhg.2016.03.015

PMCID:: PMC4833436

Abstract Article PDF–654K

Select item 442433320.

Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum

Corina Russwurm, Doris Koesling, Michael Russwurm

J Biol Chem. 2015 May 8; 290(19): 11936–11947. Published online 2015 Mar 11. doi: 10.1074/jbc.M114.595769

PMCID:: PMC4424333

Abstract Article PDF–1.2M

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