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Items: 1 to 20 of 26

1.
Uridine diphosphate glucuronosyltransferase 1A1 prevents the progression of liver injury
Jin-Lian Jiang, Yi-Yang Zhou, Wei-Wei Zhong, Lin-Yan Luo, Si-Ying Liu, Xiao-Yu Xie, Mao-Yuan Mu, Zhi-Gang Jiang, Yuan Xue, Jian Zhang, Yi-Huai He
World J Gastroenterol. 2024 Mar 7; 30(9): 1189–1212. Published online 2024 Mar 7. doi: 10.3748/wjg.v30.i9.1189
PMCID:
PMC10989491
AbstractArticlePDF–19M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR
Xiaojing Yang, André A. Weber, Elvira Mennillo, Miles Paszek, Samantha Wong, Sabrina Le, Jia Ying Ashley Teo, Max Chang, Christopher W. Benner, Robert H. Tukey, Shujuan Chen
J Biol Chem. 2023 Mar; 299(3): 102955. Published online 2023 Jan 30. doi: 10.1016/j.jbc.2023.102955
PMCID:
PMC9996368
AbstractArticlePDF–2.2M
4.
Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease
Evelyn A. Bates, Zachary A. Kipp, Genesee J. Martinez, Olufunto O. Badmus, Mangala M. Soundarapandian, Donald Foster, Mei Xu, Justin F. Creeden, Jennifer R. Greer, Andrew J. Morris, David E. Stec, Terry D. Hinds, Jr.
Biomolecules. 2023 Feb; 13(2): 252. Published online 2023 Jan 29. doi: 10.3390/biom13020252
PMCID:
PMC9953728
AbstractArticlePDF–4.1M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases
Alessia De Caneva, Fabiola Porro, Giulia Bortolussi, Riccardo Sola, Michela Lisjak, Adi Barzel, Mauro Giacca, Mark A. Kay, Kristian Vlahoviček, Lorena Zentilin, Andrés F. Muro
JCI Insight. 2019 Aug 8; 4(15): e128863. Published online 2019 Aug 8. doi: 10.1172/jci.insight.128863
PMCID:
PMC6693827
AbstractArticlePDF–18M
7.
Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma
Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe
Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050
PMCID:
PMC6602407
AbstractArticlePDF–3.5M
8.
Arsenic modifies serotonin metabolism through glucuronidation in pancreatic β-cells
Christopher M. Carmean, Norihide Yokoi, Harumi Takahashi, Okechi S. Oduori, Christie Kang, Akiko Kanagawa, Andrew G. Kirkley, Guirong Han, Michael Landeche, Shihomi Hidaka, Miki Katoh, Robert M. Sargis, Susumu Seino
Am J Physiol Endocrinol Metab. 2019 Mar 1; 316(3): E464–E474. Published online 2018 Dec 18. doi: 10.1152/ajpendo.00302.2018
PMCID:
PMC6459295
AbstractArticle
9.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
10.
Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each
Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn
PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823
PMCID:
PMC6231638
AbstractArticlePDF–3.8M
11.
LATS1 and LATS2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ
Jing Yi, Li Lu, Kilangsungla Yanger, Wenqi Wang, Bo Hwa Sohn, Ben Z. Stanger, Min Zhang, James F. Martin, Jaffer A. Ajani, Junjie Chen, Ju-Seog Lee, Shumei Song, Randy L. Johnson
Hepatology. Author manuscript; available in PMC 2018 Mar 22.
Published in final edited form as: Hepatology. 2016 Nov; 64(5): 1757–1772. Published online 2016 Sep 30. doi: 10.1002/hep.28768
PMCID:
PMC5863546
AbstractArticlePDF–873K
12.
UDP-Glucuronosyltransferase 1a Enzymes Are Present and Active in the Mouse Blastocyst
Abby C. Collier, Yasuhiro Yamauchi, Brittany L.M. Sato, Luc R.A. Rougée, Monika A. Ward
Drug Metab Dispos. 2014 Nov; 42(11): 1921–1925. Published online 2014 Nov. doi: 10.1124/dmd.114.059766
PMCID:
PMC4201130
AbstractArticlePDF–372K
13.
Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11)
Shujuan Chen, Mei-Fei Yueh, Cyril Bigo, Olivier Barbier, Kepeng Wang, Michael Karin, Nghia Nguyen, Robert H. Tukey
Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47): 19143–19148. Published online 2013 Nov 4. doi: 10.1073/pnas.1319123110
PMCID:
PMC3839688
AbstractArticlePDF–1.0M
14.
Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer
Giulia Bortolussi, Lorena Zentilin, Gabriele Baj, Pablo Giraudi, Cristina Bellarosa, Mauro Giacca, Claudio Tiribelli, Andrés F. Muro
FASEB J. 2012 Mar; 26(3): 1052–1063. doi: 10.1096/fj.11-195461
PMCID:
PMC3370676
AbstractArticle
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules
Wei Zhang, Pamela A. Wearsch, Yajuan Zhu, Ralf M. Leonhardt, Peter Cresswell
Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12): 4956–4961. Published online 2011 Mar 7. doi: 10.1073/pnas.1102527108
PMCID:
PMC3064381
AbstractArticlePDF–633K
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Effect of Oncostatin M on Uridine Diphosphate-5′-Glucuronosyltransferase 1A1 through Cross Talk with Constitutive Androstane Receptor
Hisashi Masuyama, Hideki Nakatsukasa, Yuji Hiramatsu
Mol Endocrinol. 2010 Apr; 24(4): 745–753. Published online 2010 Mar 2. doi: 10.1210/me.2009-0478
PMCID:
PMC2852350
AbstractArticle
19.
Multiple Variable First Exons: A Mechanism for Cell- and Tissue-Specific Gene Regulation
Theresa Zhang, Peter Haws, Qiang Wu
Genome Res. 2004 Jan; 14(1): 79–89. doi: 10.1101/gr.1225204
PMCID:
PMC314283
AbstractArticlePDF–421K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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