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Select item 110770831.

Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development

Eleonora Cesari, Donatella Farini, Vanessa Medici, Ingrid Ehrmann, Marika Guerra, Erika Testa, Chiara Naro, Maria Concetta Geloso, Vittoria Pagliarini, Livia La Barbera, Marcello D’Amelio, Tiziana Orsini, Stefano Farioli Vecchioli, Luca Tamagnone, Philippe Fort, Maria Teresa Viscomi, David J Elliott, Claudio Sette

Nucleic Acids Res. 2024 May 8; 52(8): 4167–4184. Published online 2024 Feb 7. doi: 10.1093/nar/gkae071

PMCID:: PMC11077083

Abstract Article PDF–3.3M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 96038603.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95697754.

Hepatic Sam68 Regulates Systemic Glucose Homeostasis and Insulin Sensitivity

Aijun Qiao, Wenxia Ma, Ying Jiang, Chaoshan Han, Baolong Yan, Junlan Zhou, Gangjian Qin

Int J Mol Sci. 2022 Oct; 23(19): 11469. Published online 2022 Sep 29. doi: 10.3390/ijms231911469

PMCID:: PMC9569775

Abstract Article PDF–2.3M

Select item 88172405.

Sam68 contributes to intestinal inflammation in experimental and human colitis

Wendy A. Goodman, Shrikanth C. Basavarajappa, Angela R. Liu, Franklin D. Staback Rodriguez, Tailor Mathes, Parameswaran Ramakrishnan

Cell Mol Life Sci. 2021 Dec; 78(23): 7635–7648. Published online 2021 Oct 24. doi: 10.1007/s00018-021-03976-7

PMCID:: PMC8817240

Abstract Article PDF–1.7M

Select item 82850326.

Ablation of Sam68 in adult mice increases thermogenesis and energy expenditure

Aijun Qiao, Wenxia Ma, Jianxin Deng, Junlan Zhou, Chaoshan Han, Eric Zhang, Chan Boriboun, Shiyue Xu, Chunxiang Zhang, Chunfa Jie, Jeong-a Kim, Kirk Habegger, Hongyu Qiu, Ting C Zhao, Jianyi Zhang, Gangjian Qin

FASEB J. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: FASEB J. 2021 Aug; 35(8): e21772. doi: 10.1096/fj.202100021R

PMCID:: PMC8285032

Abstract Article PDF–1.8M

Select item 81850847.

Sam68 promotes hepatic gluconeogenesis via CRTC2

Aijun Qiao, Junlan Zhou, Shiyue Xu, Wenxia Ma, Chan Boriboun, Teayoun Kim, Baolong Yan, Jianxin Deng, Liu Yang, Eric Zhang, Yuhua Song, Yongchao C. Ma, Stephane Richard, Chunxiang Zhang, Hongyu Qiu, Kirk M. Habegger, Jianyi Zhang, Gangjian Qin

Nat Commun. 2021; 12: 3340. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23624-9

PMCID:: PMC8185084

Abstract Article PDF–3.0M

Select item 74093718.

Sam68 splicing regulation contributes to motor unit establishment in the postnatal skeletal muscle

Elisa De Paola, Laura Forcina, Laura Pelosi, Simona Pisu, Piergiorgio La Rosa, Eleonora Cesari, Carmine Nicoletti, Luca Madaro, Neri Mercatelli, Filippo Biamonte, Annalisa Nobili, Marcello D’Amelio, Marco De Bardi, Elisabetta Volpe, Daniela Caporossi, Claudio Sette, Antonio Musarò, Maria Paola Paronetto

Life Sci Alliance. 2020 Oct; 3(10): e201900637. Published online 2020 Aug 4. doi: 10.26508/lsa.201900637

PMCID:: PMC7409371

Abstract Article PDF–3.2M

Select item 69939259.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 695445010.

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization

Vittoria Pagliarini, Ariane Jolly, Pamela Bielli, Valentina Di Rosa, Pierre De la Grange, Claudio Sette

Nucleic Acids Res. 2020 Jan 24; 48(2): 633–645. Published online 2019 Nov 28. doi: 10.1093/nar/gkz1117

PMCID:: PMC6954450

Abstract Article PDF–3.7M

Select item 690918211.

SAM68-Specific Splicing Is Required for Proper Selection of Alternative 3′ UTR Isoforms in the Nervous System

Yoko Iijima, Masami Tanaka, Satoko Suzuki, David Hauser, Masayuki Tanaka, Chisa Okada, Masatoshi Ito, Noriko Ayukawa, Yuji Sato, Masato Ohtsuka, Peter Scheiffele, Takatoshi Iijima

iScience. 2019 Dec 20; 22: 318–335. Published online 2019 Nov 16. doi: 10.1016/j.isci.2019.11.028

PMCID:: PMC6909182

Abstract Article PDF–9.8M

Select item 688906912.

Sam68 impedes the recovery of arterial injury by augmenting inflammatory response

Shuling Han, Shiyue Xu, Junlan Zhou, Aijun Qiao, Chan Boriboun, Wenxia Ma, Huadong Li, Dauren Biyashev, Liu Yang, Eric Zhang, Qinghua Liu, Shayi Jiang, Ting C Zhao, Prasanna Krishnamurthy, Chunxiang Zhang, Stéphane Richard, Hongyu Qiu, Jianyi Zhang, Gangjian Qin

J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: J Mol Cell Cardiol. 2019 Dec; 137: 82–92. Published online 2019 Oct 19. doi: 10.1016/j.yjmcc.2019.10.003

PMCID:: PMC6889069

Abstract Article PDF–1.4M

Select item 687177013.

Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons

Matthew E. Klein, Thomas J. Younts, Carmen Freire Cobo, Adina R. Buxbaum, Jonathan Aow, Hediye Erdjument-Bromage, Stéphane Richard, Roberto Malinow, Thomas A. Neubert, Robert H. Singer, Pablo E. Castillo, Bryen A. Jordan

Cell Rep. Author manuscript; available in PMC 2019 Nov 21.

Published in final edited form as: Cell Rep. 2019 Nov 12; 29(7): 1789–1799.e6. doi: 10.1016/j.celrep.2019.10.030

PMCID:: PMC6871770

Abstract Article PDF–2.4M

Select item 679247914.

Sam68 is required for the growth and survival of nonmelanoma skin cancer

Kai Fu, Xin Sun, Xue Xia, Ryan P. Hobbs, Yajuan Guo, Pierre A. Coulombe, Fengyi Wan

Cancer Med. 2019 Oct; 8(13): 6106–6113. Published online 2019 Aug 22. doi: 10.1002/cam4.2513

PMCID:: PMC6792479

Abstract Article PDF–680K

Select item 675515515.

Sam68 mediates high glucose-induced podocyte apoptosis through modulation of Bax/Bcl-2

Yuyu Chen, Li Zhang, Shuangxin Liu, Binfeng Yao, Hong Zhang, Shun Liang, Jianchao Ma, Xinling Liang, Wei Shi

Mol Med Rep. 2019 Oct; 20(4): 3728–3734. Published online 2019 Aug 21. doi: 10.3892/mmr.2019.10601

PMCID:: PMC6755155

Abstract Article PDF–1.0M

Select item 674809916.

The RNA binding protein Sam68 controls T helper 1 differentiation and anti-mycobacterial response through modulation of miR-29

Elisabetta Volpe, Eleonora Cesari, Neri Mercatelli, Rosella Cicconi, Marco De Bardi, Alessia Capone, Davide Bonvissuto, Maurizio Fraziano, Maurizio Mattei, Luca Battistini, Maria Paola Paronetto, Claudio Sette

Cell Death Differ. 2019 Jun; 26(6): 1169–1180. Published online 2018 Sep 26. doi: 10.1038/s41418-018-0201-9

PMCID:: PMC6748099

Abstract Article PDF–1.6M

Select item 669084017.

A Sam68-dependent alternative splicing program shapes postsynaptic protein complexes

Harald Witte, Dietmar Schreiner, Peter Scheiffele

Eur J Neurosci. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Eur J Neurosci. 2019 Jun 1; 49(11): 1436–1453. Published online 2019 Jan 29. doi: 10.1111/ejn.14332

PMCID:: PMC6690840

Abstract Article PDF–2.4M

Select item 660230018.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 660091319.

β-Actin mRNA interactome mapping by proximity biotinylation

Joyita Mukherjee, Orit Hermesh, Carolina Eliscovich, Nicolas Nalpas, Mirita Franz-Wachtel, Boris Maček, Ralf-Peter Jansen

Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12863–12872. Published online 2019 Jun 12. doi: 10.1073/pnas.1820737116

PMCID:: PMC6600913

Abstract Article PDF–2.4M

Select item 648654420.

SAM68 interaction with U1A modulates U1 snRNP recruitment and regulates mTor pre-mRNA splicing

Suryasree Subramania, Laurence M Gagné, Sébastien Campagne, Victoire Fort, Julia O’Sullivan, Karel Mocaer, Miki Feldmüller, Jean-Yves Masson, Frédéric H T Allain, Samer M Hussein, Marc-Étienne Huot

Nucleic Acids Res. 2019 May 7; 47(8): 4181–4197. Published online 2019 Feb 15. doi: 10.1093/nar/gkz099

PMCID:: PMC6486544

Abstract Article PDF–5.5M

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