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Items: 1 to 20 of 30

1.
Maternal thyroid hormone receptor β activation in mice sparks brown fat thermogenesis in the offspring
Rebecca Oelkrug, Lisbeth Harder, Mehdi Pedaran, Anne Hoffmann, Beke Kolms, Julica Inderhees, Sogol Gachkar, Julia Resch, Kornelia Johann, Olaf Jöhren, Kerstin Krause, Jens Mittag
Nat Commun. 2023; 14: 6742. Published online 2023 Oct 24. doi: 10.1038/s41467-023-42425-w
PMCID:
PMC10597992
AbstractArticlePDF–1.8M
2.
Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System
Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang
eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698
PMCID:
PMC10365985
AbstractArticlePDF–5.4M
3.
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
Cheng Zhang, Mengnan Shi, Woonghee Kim, Muhammad Arif, Martina Klevstig, Xiangyu Li, Hong Yang, Cemil Bayram, Ismail Bolat, Özlem Özdemir Tozlu, Ahmet Hacımuftuoglu, Serkan Yıldırım, Jihad Sebhaoui, Shazia Iqbal, Yongjun Wei, Xiaojing Shi, Jens Nielsen, Hasan Turkez, Mathias Uhlen, Jan Boren, Adil Mardinoglu
eBioMedicine. 2022 Sep; 83: 104214. Published online 2022 Aug 18. doi: 10.1016/j.ebiom.2022.104214
Correction in:
eBioMedicine. 2024 Jul; 105: 105224.
PMCID:
PMC9420484
AbstractArticlePDF–4.4M
4.
Liver homeostasis is maintained by midlobular zone 2 hepatocytes
Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu
Science. Author manuscript; available in PMC 2021 Oct 7.
Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625
PMCID:
PMC8496420
AbstractArticlePDF–6.4M
5.
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner
Karthickeyan Chella Krishnan, Raquel R. Floyd, Simon Sabir, Dulshan W. Jayasekera, Paola V. Leon-Mimila, Anthony E. Jones, Angel A. Cortez, Varun Shravah, Miklós Péterfy, Linsey Stiles, Samuel Canizales-Quinteros, Ajit S. Divakaruni, Adriana Huertas-Vazquez, Aldons J. Lusis
Cell Mol Gastroenterol Hepatol. 2021; 11(2): 389–406. Published online 2020 Sep 14. doi: 10.1016/j.jcmgh.2020.09.004
PMCID:
PMC7788245
AbstractArticlePDF–4.6M
6.
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase
Roger W. Hunter, Curtis C. Hughey, Louise Lantier, Elias I. Sundelin, Mark Peggie, Elton Zeqiraj, Frank Sicheri, Niels Jessen, David H. Wasserman, Kei Sakamoto
Nat Med. Author manuscript; available in PMC 2019 Feb 27.
Published in final edited form as: Nat Med. 2018 Sep; 24(9): 1395–1406. Published online 2018 Aug 27. doi: 10.1038/s41591-018-0159-7
PMCID:
PMC6207338
AbstractArticlePDF–2.3M
7.
The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria
Aurélie Laroque, Gundula Min-Oo, Mifong Tam, Prem Ponka, Mary M. Stevenson, Philippe Gros
PLoS One. 2017; 12(5): e0177818. Published online 2017 May 18. doi: 10.1371/journal.pone.0177818
PMCID:
PMC5436716
AbstractArticlePDF–8.0M
8.
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development
Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla
Dev Cell. 2017 Feb 27; 40(4): 331–341.e4. doi: 10.1016/j.devcel.2017.01.015
PMCID:
PMC5337618
AbstractArticle
9.
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series
Caitlyn E. Bowman, Liang Zhao, Thomas Hartung, Michael J. Wolfgang
Mol Cell Biol. 2016 Aug 1; 36(15): 2089–2104. Prepublished online 2016 May 23. Published online 2016 Jul 14. doi: 10.1128/MCB.00166-16
PMCID:
PMC4946427
AbstractArticlePDF–3.4M
10.
Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
Talya L. Dayton, Vasilena Gocheva, Kathryn M. Miller, William J. Israelsen, Arjun Bhutkar, Clary B. Clish, Shawn M. Davidson, Alba Luengo, Roderick T. Bronson, Tyler Jacks, Matthew G. Vander Heiden
Genes Dev. 2016 May 1; 30(9): 1020–1033. doi: 10.1101/gad.278549.116
PMCID:
PMC4863734
AbstractArticlePDF–583K
11.
Energetic coupling between an oxidizable cysteine and the phosphorylatable N-terminus of human liver pyruvate kinase
Todd Holyoak, Bing Zhang, Junpeng Deng, Qingling Tang, Charulata B. Prasannan, Aron W. Fenton
Biochemistry. Author manuscript; available in PMC 2014 Jan 22.
Published in final edited form as: Biochemistry. 2013 Jan 22; 52(3): 466–476. Published online 2013 Jan 11. doi: 10.1021/bi301341r
PMCID:
PMC3572911
AbstractArticlePDF–1.4M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Krüppel-Like Factor 1 (KLF1), KLF2, and Myc Control a Regulatory Network Essential for Embryonic Erythropoiesis
Christopher J. Pang, Wafaa Lemsaddek, Yousef N. Alhashem, Cornelius Bondzi, Latasha C. Redmond, Nicolas Ah-Son, Catherine I. Dumur, Kellie J. Archer, Jack L. Haar, Joyce A. Lloyd, Marie Trudel
Mol Cell Biol. 2012 Jul; 32(13): 2628–2644. doi: 10.1128/MCB.00104-12
PMCID:
PMC3434496
AbstractArticlePDF–1.8M
14.
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang
Neuron. Author manuscript; available in PMC 2013 Jul 12.
Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024
PMCID:
PMC3432264
AbstractArticlePDF–4.9M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
17.
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice
M. Estela Campanella, Haiyan Chu, Nancy J. Wandersee, Luanne L. Peters, Narla Mohandas, Diana M. Gilligan, Philip S. Low
Blood. 2008 Nov 1; 112(9): 3900–3906. Prepublished online 2008 Aug 12. doi: 10.1182/blood-2008-03-146159
PMCID:
PMC2572807
AbstractArticle
18.
Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus
Gundula Min-Oo, Anny Fortin, Giuseppina Pitari, Mifong Tam, Mary M. Stevenson, Philippe Gros
J Exp Med. 2007 Mar 19; 204(3): 511–524. doi: 10.1084/jem.20061252
PMCID:
PMC2137903
AbstractArticlePDF–2.6M
19.
Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice
Marie-France Roy, Noémie Riendeau, Christian Bédard, Pierre Hélie, Gundula Min-Oo, Karine Turcotte, Philippe Gros, François Canonne-Hergaux, Danielle Malo
J Exp Med. 2007 Nov 26; 204(12): 2949–2961. doi: 10.1084/jem.20062606
PMCID:
PMC2118530
AbstractArticlePDF–3.2M
20.
An analysis of expression patterns of genes encoding proteins with catalytic activities
Murat Cankaya, Ana Martinez Hernandez, Mehmet Ciftci, Sukru Beydemir, Hasan Ozdemir, Harun Budak, Ilhami Gulcin, Veysel Comakli, Tufan Emircupani, Deniz Ekinci, Muslum Kuzu, Qiuhong Jiang, Gregor Eichele, Omer Irfan Kufrevioglu
BMC Genomics. 2007; 8: 232. Published online 2007 Jul 12. doi: 10.1186/1471-2164-8-232
PMCID:
PMC1976134
AbstractArticlePDF–1.5M

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