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Select item 112313301.

Extracellular C1qbp inhibits myogenesis by suppressing NFATc1

Jin-Man Kim, Ho Kyoung Kim, Han Jin Cho, Sung-Ah Moon, Yewon Kim, Jeong Yeon Hong, Seung Hun Lee, Kyunggon Kim, Jung-Min Koh

Sci Rep. 2024; 14: 15678. Published online 2024 Jul 8. doi: 10.1038/s41598-024-66549-1

PMCID:: PMC11231330

Abstract Article PDF–14M

Select item 111057762.

Rab44, a novel large Rab GTPase, negatively regulates osteoclast differentiation by modulating intracellular calcium levels followed by NFATc1 activation

Yu Yamaguchi, Eiko Sakai, Kuniaki Okamoto, Hiroshi Kajiya, Koji Okabe, Mariko Naito, Tomoko Kadowaki, Takayuki Tsukuba

Cell Mol Life Sci. 2018 Jan; 75(1): 33–48. Published online 2017 Aug 8. doi: 10.1007/s00018-017-2607-9

PMCID:: PMC11105776

Abstract Article PDF–2.0M

Select item 110990863.

Endocardial HDAC3 is required for myocardial trabeculation

Jihyun Jang, Mette Bentsen, Ye Jun Kim, Erick Kim, Vidu Garg, Chen-Leng Cai, Mario Looso, Deqiang Li

Nat Commun. 2024; 15: 4166. Published online 2024 May 16. doi: 10.1038/s41467-024-48362-6

PMCID:: PMC11099086

Abstract Article PDF–3.3M

Select item 109601334.

High paternal homocysteine causes ventricular septal defects in mouse offspring

Lian Liu, Xuan Zhang, Hao-Ran Geng, Ya-Nan Qiao, Yong-Hao Gui, Jian-Yuan Zhao

iScience. 2024 Apr 19; 27(4): 109447. Published online 2024 Mar 7. doi: 10.1016/j.isci.2024.109447

PMCID:: PMC10960133

Abstract Article PDF–4.8M

Select item 108350435.

Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis

Zheng Zhang, Yichen Meng, Tao Lin, Zhanrong Zhang, Zhengbo Tao, Haozan Yin, Fu Yang, Xuhui Zhou

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2313656121. Published online 2024 Jan 22. doi: 10.1073/pnas.2313656121

PMCID:: PMC10835043

Abstract Article PDF–13M

Select item 108227766.

The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of NFATc1 expression

Steve Stegen, Karen Moermans, Ingrid Stockmans, Bernard Thienpont, Geert Carmeliet

Nat Metab. 2024; 6(1): 141–152. Published online 2024 Jan 10. doi: 10.1038/s42255-023-00948-y

PMCID:: PMC10822776

Abstract Article PDF–11M

Select item 106629727.

Myocardial equation M1

-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation

Yidong Wang, Pengfei Lu, Bingruo Wu, Dario F. Riascos-Bernal, Nicholas E.S. Sibinga, Tomas Valenta, Konrad Basler, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: J Mol Cell Cardiol. 2018 Oct; 123: 150–158. Published online 2018 Sep 8. doi: 10.1016/j.yjmcc.2018.09.001

PMCID:: PMC10662972

Abstract Article PDF–2.2M

Select item 106202258.

Essentiality of Nfatc1 short isoform in osteoclast differentiation and its self-regulation

Yasuhiro Omata, Hideyuki Tachibana, Yoshimi Aizaki, Toshihide Mimura, Kojiro Sato

Sci Rep. 2023; 13: 18797. Published online 2023 Nov 1. doi: 10.1038/s41598-023-45909-3

PMCID:: PMC10620225

Abstract Article PDF–2.4M

Select item 106117309.

Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming

Hao Wu, Xiufeng Zhao, Sophia M. Hochrein, Miriam Eckstein, Gabriela F. Gubert, Konrad Knöpper, Ana Maria Mansilla, Arman Öner, Remi Doucet-Ladevèze, Werner Schmitz, Bart Ghesquière, Sebastian Theurich, Jan Dudek, Georg Gasteiger, Alma Zernecke, Sebastian Kobold, Wolfgang Kastenmüller, Martin Vaeth

Nat Commun. 2023; 14: 6858. Published online 2023 Oct 27. doi: 10.1038/s41467-023-42634-3

PMCID:: PMC10611730

Abstract Article PDF–3.5M

Select item 1054730010.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 1049282811.

Cell diversity and plasticity during atrioventricular heart valve EMTs

Jeremy Lotto, Rebecca Cullum, Sibyl Drissler, Martin Arostegui, Victoria C. Garside, Bettina M. Fuglerud, Makenna Clement-Ranney, Avinash Thakur, T. Michael Underhill, Pamela A. Hoodless

Nat Commun. 2023; 14: 5567. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41279-6

PMCID:: PMC10492828

Abstract Article PDF–4.2M

Select item 1029719312.

Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis

Peilei Lu, Danyu Zhang, Fan Ding, Jialu Ma, Yang K. Xiang, Meimi Zhao

Cells. 2023 Jun; 12(12): 1667. Published online 2023 Jun 19. doi: 10.3390/cells12121667

PMCID:: PMC10297193

Abstract Article PDF–3.4M

Select item 1019788913.

The deubiquitinase UCHL1 negatively controls osteoclastogenesis by regulating TAZ/NFATC1 signalling

Zhenhua Feng, Siyue Tao, Zhaobo Huang, Bingjie Zheng, Xiangxi Kong, Yufeng Xiang, Qibin Zhang, Haixin Song, Zhikun Xu, Xiaoan Wei, Fengdong Zhao, Jian Chen

Int J Biol Sci. 2023; 19(8): 2319–2332. Published online 2023 Apr 24. doi: 10.7150/ijbs.82152

PMCID:: PMC10197889

Abstract Article PDF–7.7M

Select item 1018405014.

NFATc1-mediated expression of SLC7A11 drives sensitivity to TXNRD1 inhibitors in osteoclast precursors

Zeyuan Zhong, Chongjing Zhang, Shuo Ni, Miao Ma, Xiaomeng Zhang, Weicong Sang, Tao Lv, Zhi Qian, Chengqing Yi, Baoqing Yu

Redox Biol. 2023 Jul; 63: 102711. Published online 2023 Apr 29. doi: 10.1016/j.redox.2023.102711

PMCID:: PMC10184050

Abstract Article PDF–13M

Select item 1011049215.

Single cell evaluation of endocardial Hand2 gene regulatory networks reveals HAND2-dependent pathways that impact cardiac morphogenesis

Rajani M. George, Beth A. Firulli, Ram Podicheti, Douglas B. Rusch, Brandon J. Mannion, Len A. Pennacchio, Marco Osterwalder, Anthony B. Firulli

Development. 2023 Feb 1; 150(3): dev201341. Published online 2023 Feb 6. doi: 10.1242/dev.201341

PMCID:: PMC10110492

Abstract Article

Select item 1007601916.

NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation

Fan Zhang, Yuanyuan Wang, Ying Zhao, Manqi Wang, Bin Zhou, Bin Zhou, Xianpeng Ge

eLife. 2023; 12: e81569. Published online 2023 Feb 15. doi: 10.7554/eLife.81569

PMCID:: PMC10076019

Abstract Article PDF–12M

Select item 1006637917.

Endothelial deletion of PTBP1 disrupts ventricular chamber development

Hongyu Liu, Ran Duan, Xiaoyu He, Jincu Qi, Tianming Xing, Yahan Wu, Liping Zhou, Lingling Wang, Yujing Shao, Fulei Zhang, Huixing Zhou, Xingdong Gu, Bowen Lin, Yuanyuan Liu, Yan Wang, Yi Liu, Li Li, Dandan Liang, Yi-Han Chen

Nat Commun. 2023; 14: 1796. Published online 2023 Mar 31. doi: 10.1038/s41467-023-37409-9

PMCID:: PMC10066379

Abstract Article PDF–7.8M

Select item 1006444018.

NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming

Zhe Zhang, Xin Wang, Feda H. Hamdan, Anna Likhobabina, Shilpa Patil, Lena Aperdannier, Madhobi Sen, Jacobe Traub, Albrecht Neesse, André Fischer, Argyris Papantonis, Shiv K. Singh, Volker Ellenrieder, Steven A. Johnsen, Elisabeth Hessmann

Cell Mol Gastroenterol Hepatol. 2023; 15(5): 1219–1246. Published online 2023 Feb 8. doi: 10.1016/j.jcmgh.2023.01.015

PMCID:: PMC10064440

Abstract Article PDF–10M

Select item 1001174819.

NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation

Sabrina Giampaolo, Cristina M. Chiarolla, Konrad Knöpper, Martin Vaeth, Matthias Klein, Azeem Muhammad, Tobias Bopp, Friederike Berberich-Siebelt, Amiya K. Patra, Edgar Serfling, Stefan Klein-Hessling

iScience. 2023 Mar 17; 26(3): 106234. Published online 2023 Feb 19. doi: 10.1016/j.isci.2023.106234