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Items: 1 to 20 of 57

1.
Dimorphic effect of TFE3 in determining mitochondrial and lysosomal content in muscle following denervation
Ashley N. Oliveira, Jonathan M. Memme, Jenna Wong, David A. Hood
Skelet Muscle. 2024; 14: 7. Published online 2024 Apr 20. doi: 10.1186/s13395-024-00339-1
PMCID:
PMC11031958
AbstractArticlePDF–2.2M
2.
Mitf regulates gene expression networks implicated in B cell homeostasis, germinal center responses, and tolerance
Abhimanyu Amarnani, Maria Lopez-Ocasio, Ramile Dilshat, Kamala Anumukonda, Jonathan Davila, Nikita Malakhov, Chongmin Huan, Erna Magnusdottir, Eirikur Steingrimsson, Christopher A. Roman
Front Immunol. 2024; 15: 1339325. Published online 2024 Feb 20. doi: 10.3389/fimmu.2024.1339325
PMCID:
PMC10912573
AbstractArticlePDF–9.4M
3.
Reprogramming tumour-associated macrophages to outcompete cancer cells
Xian Zhang, Shun Li, Isha Malik, Mytrang H. Do, Liangliang Ji, Chun Chou, Wei Shi, Kristelle J. Capistrano, Jing Zhang, Ting-Wei Hsu, Briana G. Nixon, Ke Xu, Xinxin Wang, Andrea Ballabio, Laura S. Schmidt, W. Marston Linehan, Ming O. Li
Nature. Author manuscript; available in PMC 2023 Dec 14.
Published in final edited form as: Nature. 2023 Jul; 619(7970): 616–623. Published online 2023 Jun 28. doi: 10.1038/s41586-023-06256-5
PMCID:
PMC10719927
AbstractArticlePDF–5.6M
4.
Dectin-1/CARD9 induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung
Mariano A. Aufiero, Neta Shlezinger, Mergim Gjonbalaj, Kathleen A. M. Mills, Andrea Ballabio, Tobias M. Hohl
Infect Immun. 2023 Nov; 91(11): e00217-23. Published online 2023 Oct 20. doi: 10.1128/iai.00217-23
PMCID:
PMC10652993
AbstractArticlePDF–802K
5.
TFEB and TFE3 control glucose homeostasis by regulating insulin gene expression
Adrien Pasquier, Nunzia Pastore, Luca D'Orsi, Rita Colonna, Alessandra Esposito, Veronica Maffia, Rossella De Cegli, Margherita Mutarelli, Susanna Ambrosio, Gennaro Tufano, Antonio Grimaldi, Marcella Cesana, Davide Cacchiarelli, Nathalie Delalleau, Gennaro Napolitano, Andrea Ballabio
EMBO J. 2023 Nov; 42(21): e113928. Published online 2023 Sep 15. doi: 10.15252/embj.2023113928
PMCID:
PMC10620765
AbstractArticlePDF–9.0M
6.
TFEB and TFE3 drive kidney cystogenesis and tumorigenesis
Chiara Di Malta, Angela Zampelli, Letizia Granieri, Claudia Vilardo, Rossella De Cegli, Laura Cinque, Edoardo Nusco, Salvatore Pece, Daniela Tosoni, Francesca Sanguedolce, Nicolina Cristina Sorrentino, Maria J Merino, Deborah Nielsen, Ramaprasad Srinivasan, Mark W Ball, Christopher J Ricketts, Cathy D Vocke, Martin Lang, Baktiar Karim, Luisa Lanfrancone, Laura S Schmidt, W Marston Linehan, Andrea Ballabio
EMBO Mol Med. 2023 May; 15(5): e16877. Published online 2023 Mar 29. doi: 10.15252/emmm.202216877
PMCID:
PMC10165358
AbstractArticlePDF–5.8M
7.
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1
Bridget S. Gosis, Shogo Wada, Chelsea Thorsheim, Kristina Li, Sunhee Jung, Joshua H. Rhoades, Yifan Yang, Jeffrey Brandimarto, Li Li, Kahealani Uehara, Cholsoon Jang, Matthew Lanza, Nathan B. Sanford, Marc R. Bornstein, Sunhye Jeong, Paul M. Titchenell, Sudha B. Biddinger, Zoltan Arany
Science. Author manuscript; available in PMC 2023 Apr 15.
Published in final edited form as: Science. 2022 Apr 15; 376(6590): eabf8271. Published online 2022 Apr 15. doi: 10.1126/science.abf8271
PMCID:
PMC9811404
AbstractArticlePDF–2.3M
8.
Disruption of Trip11 in cranial neural crest cells is associated with increased ER and Golgi stress contributing to skull defects in mice
Hiroyuki Yamaguchi, Matthew D. Meyer, Li He, Yoshihiro Komatsu
Dev Dyn. Author manuscript; available in PMC 2023 Jul 1.
Published in final edited form as: Dev Dyn. 2022 Jul; 251(7): 1209–1222. Published online 2022 Feb 18. doi: 10.1002/dvdy.461
PMCID:
PMC9250589
AbstractArticlePDF–2.3M
9.
A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Akiyoshi Hirayama, Ayako Nakamura-Ishizu, Terumasa Umemoto, Michihiro Hashimoto, Kunio Nagashima, Tomoyoshi Soga, Martin Lang, Laura S. Schmidt, W. Marston Linehan, Toshio Suda
Cell Rep. Author manuscript; available in PMC 2021 Sep 23.
Published in final edited form as: Cell Rep. 2020 Feb 11; 30(6): 1823–1834.e5. doi: 10.1016/j.celrep.2020.01.042
PMCID:
PMC8459211
AbstractArticlePDF–3.0M
10.
TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress
Kailiang Zhou, Zhilong Zheng, Yao Li, Wen Han, Jing Zhang, Yuqin Mao, Huanwen Chen, Wanying Zhang, Mi Liu, Ling Xie, Hongyu Zhang, Huazi Xu, Jian Xiao
Theranostics. 2020; 10(20): 9280–9302. Published online 2020 Jul 23. doi: 10.7150/thno.46566
PMCID:
PMC7415792
AbstractArticlePDF–4.1M
11.
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco
Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006
PMCID:
PMC6994247
AbstractArticlePDF–1.6M
12.
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB
Yusha Wang, Yewei Huang, Jiaqi Liu, Jinna Zhang, Mingming Xu, Zhiyuan You, Chao Peng, Zhefeng Gong, Wei Liu
EMBO Rep. 2020 Jan 7; 21(1): e48335. Published online 2019 Nov 21. doi: 10.15252/embr.201948335
PMCID:
PMC6945067
AbstractArticlePDF–3.1M
13.
Folliculin Interacting Protein-1 Maintains Metabolic Homeostasis During B Cell Development by Modulating AMPK, mTORC1, and TFE3
Julita A. Ramίrez, Terri Iwata, Heon Park, Mark Tsang, Janella Kang, Katy Cui, Winnie Kwong, Richard G. James, Masaya Baba, Laura S. Schmidt, Brian M. Iritani
J Immunol. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: J Immunol. 2019 Dec 1; 203(11): 2899–2908. Published online 2019 Nov 1. doi: 10.4049/jimmunol.1900395
PMCID:
PMC6864314
AbstractArticlePDF–1.6M
14.
Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis
Shaogui Wang, Hong-Min Ni, Xiaojuan Chao, Hua Wang, Brian Bridges, Sean Kumer, Timothy Schmitt, Olga Mareninova, Anna Gukovskaya, Robert C. De Lisle, Andrea Ballabio, Pal Pacher, Wen-Xing Ding
Autophagy. 2019; 15(11): 1954–1969. Published online 2019 Mar 30. doi: 10.1080/15548627.2019.1596486
PMCID:
PMC6844531
AbstractArticlePDF–5.5M
15.
TFE3 Xp11.2 translocation renal cell carcinoma mouse model reveals novel therapeutic targets and identifies GPNMB as a diagnostic marker for human disease
Masaya Baba, Mitsuko Furuya, Takanobu Motoshima, Martin Lang, Shintaro Funasaki, Wenjuan Ma, Hong-Wei Sun, Hisashi Hasumi, Ying Huang, Ikuma Kato, Tsuyoshi Kadomatsu, Yorifumi Satou, Nicole Morris, Baktiar O. Karim, Lilia Ileva, Joseph D. Kalen, Luh Ade Wilan Krisna, Yukiko Hasumi, Aiko Sugiyama, Ryoma Kurahashi, Koshiro Nishimoto, Masafumi Oyama, Yoji Nagashima, Naoto Kuroda, Kimi Araki, Masatoshi Eto, Masahiro Yao, Tomomi Kamba, Toshio Suda, Yuichi Oike, Laura S. Schmidt, W. Marston Linehan
Mol Cancer Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Mol Cancer Res. 2019 Aug; 17(8): 1613–1626. Published online 2019 May 1. doi: 10.1158/1541-7786.MCR-18-1235
PMCID:
PMC6679785
AbstractArticlePDF–2.0M
16.
Nutrient‐sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock
Nunzia Pastore, Anna Vainshtein, Niculin J Herz, Tuong Huynh, Lorenzo Brunetti, Tiemo J Klisch, Margherita Mutarelli, Patrizia Annunziata, Kenichiro Kinouchi, Nicola Brunetti‐Pierri, Paolo Sassone‐Corsi, Andrea Ballabio
EMBO J. 2019 Jun 17; 38(12): e101347. Published online 2019 May 24. doi: 10.15252/embj.2018101347
PMCID:
PMC6576167
AbstractArticlePDF–2.0M
17.
Myeloid folliculin balances mTOR activation to maintain innate immunity homeostasis
Jia Li, Shogo Wada, Lehn K. Weaver, Chhanda Biswas, Edward M. Behrens, Zoltan Arany
JCI Insight. 2019 Mar 21; 4(6): e126939. Published online 2019 Mar 21. doi: 10.1172/jci.insight.126939
PMCID:
PMC6483010
AbstractArticlePDF–2.2M
18.
The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage
Owen A Brady, Eutteum Jeong, José A Martina, Mehdi Pirooznia, Ilker Tunc, Rosa Puertollano
eLife. 2018; 7: e40856. Published online 2018 Dec 6. doi: 10.7554/eLife.40856
PMCID:
PMC6292694
AbstractArticlePDF–6.9M
19.
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice
Jin Li, Su-Ping Deng, Gang Wei, Peng Yu
Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012
PMCID:
PMC5868181
AbstractArticlePDF–653K
20.
TRANSCRIPTIONAL ACTIVATION OF RAGD GTPASE CONTROLS mTORC1 AND PROMOTES CANCER GROWTH
Chiara Di Malta, Diletta Siciliano, Alessia Calcagni, Jlenia Monfregola, Simona Punzi, Nunzia Pastore, Andrea N. Eastes, Oliver Davis, Rossella de Cegli, Angela Zampelli, Luca G. Di Giovannantonio, Edoardo Nusco, Nick Platt, Alessandro Guida, Margret Helga Ogmundsdottir, Luisa Lanfrancone, Rushika M. Perera, Roberto Zoncu, Pier Giuseppe Pelicci, Carmine Settembre, Andrea Ballabio.
Science. Author manuscript; available in PMC 2017 Dec 16.
Published in final edited form as: Science. 2017 Jun 16; 356(6343): 1188–1192. doi: 10.1126/science.aag2553
PMCID:
PMC5730647
AbstractArticlePDF–521K

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