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Select item 113735991.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 113352032.

EphA2 promotes the transcription of KLF4 to facilitate stemness in oral squamous cell carcinoma

Junqiang Bai, Yang Chen, Yunqing Sun, Xinmiao Wang, Yifan Wang, Shutian Guo, Zhengjun Shang, Zhe Shao

Cell Mol Life Sci. 2024 Dec; 81(1): 278. Published online 2024 Jun 25. doi: 10.1007/s00018-024-05325-w

PMCID:: PMC11335203

Abstract Article PDF–13M

Select item 112750323.

The EphA2 Receptor Regulates Invasiveness and Drug Sensitivity in Canine and Human Osteosarcoma Cells

Evelyn D. Harris, Jessica C. Sharpe, Timothy Strozen, Shabnam Abdi, Maya Kliewer, Malkon G. Sanchez, Natacha S. Hogan, Valerie MacDonald-Dickinson, Franco J. Vizeacoumar, Behzad M. Toosi

Cells. 2024 Jul; 13(14): 1201. Published online 2024 Jul 16. doi: 10.3390/cells13141201

PMCID:: PMC11275032

Abstract Article PDF–2.7M

Select item 112636594.

Transmembrane helix interactions regulate oligomerization of the receptor tyrosine kinase EphA2

Daniel Wirth, Ece Özdemir, William C. Wimley, Elena B. Pasquale, Kalina Hristova

J Biol Chem. 2024 Jul; 300(7): 107441. Published online 2024 Jun 3. doi: 10.1016/j.jbc.2024.107441

PMCID:: PMC11263659

Abstract Article PDF–1.7M

Select item 112099355.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111598186.

EPHA2/EFNA1 expression in human gastric cancer

Ritsuko Nakamura, Hideki Kataoka, Naomi Sato, Masao Kanamori, Megumi Ihara, Hisaki Igarashi, Sanjar Ravshanov, You‐Jie Wang, Zhong‐You Li, Takahiro Shimamura, Toshihiko Kobayashi, Hiroyuki Konno, Kazuya Shinmura, Masamitsu Tanaka, Haruhiko Sugimura

Cancer Sci. 2005 Jan; 96(1): 42–47. Published online 2005 Jan 13. doi: 10.1111/j.1349-7006.2005.00007.x

PMCID:: PMC11159818

Abstract Article PDF–194K

Select item 111597317.

Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer

Hideki Kataoka, Hisaki Igarashi, Masao Kanamori, Megumi Ihara, Jian‐Dong Wang, You‐Jie Wang, Zhong‐You Li, Takahiro Shimamura, Toshihiko Kobayashi, Keiji Maruyama, Toshio Nakamura, Hajime Arai, Masayoshi Kajimura, Hiroyuki Hanai, Masamitsu Tanaka, Haruhiko Sugimura

Cancer Sci. 2004 Feb; 95(2): 136–141. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb03194.x

PMCID:: PMC11159731

Abstract Article PDF–745K

Select item 109902778.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 109659939.

USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway

Anan Li, Shijiang Wang, Jiangbo Nie, Shining Xiao, Xinsheng Xie, Yu Zhang, Weilai Tong, Geliang Yao, Ning Liu, Fan Dan, Zhiguo Shu, Jiaming Liu, Zhili Liu, Feng Yang

Cell Death Dis. 2024 Mar; 15(3): 235. Published online 2024 Mar 26. doi: 10.1038/s41419-024-06624-7

PMCID:: PMC10965993

Abstract Article PDF–5.4M

Select item 1094570710.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 1091686611.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 1076596112.

Claudin-1 Interacts with EPHA2 To Promote Cancer Stemness and Chemoresistance in Colorectal Cancer

Mark Primeaux, Xiangdong Liu, Saiprasad Gowrikumar, Iram Fatima, Kurt W. Fisher, Dhundy Bastola, Alex J. Vecchio, Amar B. Singh, Punita Dhawan

Cancer Lett. Author manuscript; available in PMC 2024 Nov 28.

Published in final edited form as: Cancer Lett. 2023 Nov 28; 579: 216479. Published online 2023 Nov 2. doi: 10.1016/j.canlet.2023.216479

PMCID:: PMC10765961

Abstract Article PDF–2.8M

Select item 1071342413.

EphA2 as a phase separation protein associated with ferroptosis and immune cell infiltration in colorectal cancer

Yanling Li, Qiu Peng, Lujuan Wang

Aging (Albany NY) 2023 Nov 30; 15(22): 12952–12965. Published online 2023 Nov 16. doi: 10.18632/aging.205212

PMCID:: PMC10713424

Abstract Article PDF–1.9M

Select item 1068021514.

LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2

Xue Han, Fan Shi, Shujun Guo, Yao Li, Hongtao Wang, Chuanwang Song, Shiwu Wu

World J Surg Oncol. 2023; 21: 371. Published online 2023 Nov 27. doi: 10.1186/s12957-023-03245-w

PMCID:: PMC10680215

Abstract Article PDF–4.4M

Select item 1062778615.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 1056587616.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1056492717.

Downregulation of EphA2 stability by RNF5 limits its tumor-suppressive function in HER2-negative breast cancers

Xiaojuan Li, Fan Wang, Lu Huang, Mengtian Yang, Ersheng Kuang

Cell Death Dis. 2023 Oct; 14(10): 662. Published online 2023 Oct 10. doi: 10.1038/s41419-023-06188-y

PMCID:: PMC10564927

Abstract Article PDF–5.5M

Select item 1048053518.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1034596319.

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy

Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald

Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535

PMCID:: PMC10345963

Abstract Article PDF–13M

Select item 1032325220.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

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