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Items: 1 to 20 of 97

1.
Epigenetic alteration of the NF‐κB‐inducing kinase (NIK) gene is involved in enhanced NIK expression in basal‐like breast cancer
Mizuki Yamamoto, Taku Ito, Takafumi Shimizu, Takaomi Ishida, Kentaro Semba, Shinya Watanabe, Noritaka Yamaguchi, Jun‐ichiro Inoue
Cancer Sci. 2010 Nov; 101(11): 2391–2397. Published online 2010 Aug 24. doi: 10.1111/j.1349-7006.2010.01685.x
PMCID:
PMC11158540
AbstractArticlePDF–548K
2.
Transcriptional induction of NF-κB-inducing kinase by E2F4/5 facilitates collective invasion of GBM cells
Kathryn M. Pflug, Dong W. Lee, Kassandra McFadden, Linda Herrera, Raquel Sitcheran
Sci Rep. 2023; 13: 13093. Published online 2023 Aug 11. doi: 10.1038/s41598-023-38996-9
PMCID:
PMC10421885
AbstractArticlePDF–3.8M
3.
A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells
Xue Li, Quan Jiang, Guiyu Song, Mahsa Nouri Barkestani, Qianxun Wang, Shaoxun Wang, Matthew Fan, Caodi Fang, Bo Jiang, Justin Johnson, Arnar Geirsson, George Tellides, Jordan S. Pober, Dan Jane-wit
Nat Commun. 2023; 14: 3002. Published online 2023 May 24. doi: 10.1038/s41467-023-38684-2
Correction in:
Nat Commun. 2023; 14: 3336.
Correction in:
Nat Commun. 2023; 14: 8404.
PMCID:
PMC10209169
AbstractArticlePDF–4.2M
4.
NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition
Anna Juliane Vesting, Alexander Jais, Paul Klemm, Lukas Steuernagel, Peter Wienand, Morten Fog-Tonnesen, Henning Hvid, Anna–Lena Schumacher, Christian Kukat, Hendrik Nolte, Theodoros Georgomanolis, Janine Altmüller, Manolis Pasparakis, Andreas Schmidt, Marcus Krüger, Marc Schmidt Supprian, Ari Waisman, Beate Katharina Straub, Nathanael Raschzok, Michel Bernier, Andreas L. Birkenfeld, Nadine Hövelmeyer, Jens C. Brüning, F. Thomas Wunderlich
Mol Metab. 2022 Dec; 66: 101626. Published online 2022 Nov 7. doi: 10.1016/j.molmet.2022.101626
PMCID:
PMC9676392
AbstractArticlePDF–4.0M
5.
ZFP91 promotes cell proliferation and inhibits cell apoptosis in AML via inhibiting the proteasome-dependent degradation of RIP1
Zhonghui Zhang, Liang Zhong, Wenran Dan, Xuan Chu, Chen Liu, Xu Luo, Peng Wan, Zhenyan Liu, Yang Lu, Xiao Wang, Beizhong Liu
Int J Med Sci. 2022; 19(2): 274–285. Published online 2022 Jan 1. doi: 10.7150/ijms.67436
PMCID:
PMC8795797
AbstractArticlePDF–1.5M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
NIK promotes metabolic adaptation of glioblastoma cells to bioenergetic stress
Michael L. Kamradt, Ji-Ung Jung, Kathryn M. Pflug, Dong W. Lee, Victor Fanniel, Raquel Sitcheran
Cell Death Dis. 2021 Mar; 12(3): 271. Published online 2021 Mar 15. doi: 10.1038/s41419-020-03383-z
PMCID:
PMC7960998
AbstractArticlePDF–5.3M
8.
OTUD7B suppresses Smac mimetic-induced lung cancer cell invasion and migration via deubiquitinating TRAF3
Boxiang Zhang, Chengcheng Yang, Rui Wang, Jie Wu, Yunfeng Zhang, Dapeng Liu, Xin Sun, Xiang Li, Hong Ren, Sida Qin
J Exp Clin Cancer Res. 2020; 39: 244. Published online 2020 Nov 16. doi: 10.1186/s13046-020-01751-3
PMCID:
PMC7667862
AbstractArticlePDF–4.8M
9.
Canonical, Non-Canonical and Atypical Pathways of Nuclear Factor кb Activation in Preeclampsia
Agata Sakowicz, Michalina Bralewska, Tadeusz Pietrucha, Dominika E Habrowska-Górczyńska, Agnieszka W Piastowska-Ciesielska, Agnieszka Gach, Magda Rybak-Krzyszkowska, Piotr J Witas, Hubert Huras, Mariusz Grzesiak, Lidia Biesiada
Int J Mol Sci. 2020 Aug; 21(15): 5574. Published online 2020 Aug 4. doi: 10.3390/ijms21155574
PMCID:
PMC7432517
AbstractArticlePDF–1.6M
10.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
11.
MicroRNA-98-5p Inhibits Tumorigenesis of Hepatitis B Virus-Related Hepatocellular Carcinoma by Targeting NF-κB-Inducing Kinase
Xiukun Fei, Peipei Zhang, Yu Pan, Yuanyuan Liu
Yonsei Med J. 2020 Jun 1; 61(6): 460–470. Published online 2020 May 25. doi: 10.3349/ymj.2020.61.6.460
PMCID:
PMC7256008
AbstractArticlePDF–1.4M
12.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
13.
A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes
Maria Feoktistova, Roman Makarov, Sihem Brenji, Anne T. Schneider, Guido J. Hooiveld, Tom Luedde, Martin Leverkus, Amir S. Yazdi, Diana Panayotova-Dimitrova
Cells. 2020 Feb; 9(2): 351. Published online 2020 Feb 3. doi: 10.3390/cells9020351
PMCID:
PMC7072579
AbstractArticlePDF–3.6M
14.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
15.
Conditional Activation of NF-κB Inducing Kinase (NIK) in the Osteolineage Enhances both Basal and Loading-Induced Bone Formation
Jennifer L. Davis, Linda Cox, Christine Shao, Cheng Lyu, Shaopeng Liu, Rajeev Aurora, Deborah J. Veis
J Bone Miner Res. Author manuscript; available in PMC 2020 Nov 1.
Published in final edited form as: J Bone Miner Res. 2019 Nov; 34(11): 2087–2100. Published online 2019 Jul 31. doi: 10.1002/jbmr.3819
PMCID:
PMC6854278
AbstractArticlePDF–1.1M
16.
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB
Zixu Liu, Katrina B. Mar, Natasha W. Hanners, Sofya S. Perelman, Mohammed Kanchwala, Chao Xing, John W. Schoggins, Neal M. Alto
Nature. Author manuscript; available in PMC 2019 Oct 24.
Published in final edited form as: Nature. 2019 Apr; 568(7751): 249–253. Published online 2019 Mar 20. doi: 10.1038/s41586-019-1041-6
PMCID:
PMC6812682
AbstractArticlePDF–4.2M
17.
A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas
Jeffrey R Gehlhausen, Eric Hawley, Benjamin Mark Wahle, Yongzheng He, Donna Edwards, Steven D Rhodes, Jacquelyn D Lajiness, Karl Staser, Shi Chen, Xianlin Yang, Jin Yuan, Xiaohong Li, Li Jiang, Abbi Smith, Waylan Bessler, George Sandusky, Anat Stemmer-Rachamimov, Timothy J Stuhlmiller, Steven P Angus, Gary L Johnson, Grzegorz Nalepa, Charles W Yates, D Wade Clapp, Su-Jung Park
Hum Mol Genet. 2019 Feb 15; 28(4): 572–583. Published online 2018 Oct 17. doi: 10.1093/hmg/ddy361
PMCID:
PMC6489415
AbstractArticlePDF–11M
18.
POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1
Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu
EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058
PMCID:
PMC6441868
AbstractArticlePDF–7.0M
19.
Lymphatic endothelial cells regulate B-cell homing to lymph nodes via a NIK-dependent mechanism
Jie Yang, Siya Zhang, Lingyun Zhang, Xiaoping Xie, Hui Wang, Zuliang Jie, Meidi Gu, Jin-Young Yang, Xuhong Cheng, Shao-Cong Sun
Cell Mol Immunol. 2019 Feb; 16(2): 165–177. Published online 2018 Mar 5. doi: 10.1038/cmi.2017.167
PMCID:
PMC6355805
AbstractArticlePDF–4.8M
20.
Kinase domain activation through gene rearrangement in multiple myeloma
Gareth J Morgan, Jie He, Ruslana Tytarenko, Purvi Patel, Owen W Stephens, Shan Zhong, Shayu Deshpande, Michael Bauer, Niels Weinhold, Carolina Schinke, Leo Rasche, Mark Bailey, Siraj Ali, Jeff Ross, Vincent A Miller, Phillip Stephens, Sharmilan Thanendrarajan, Maurizio Zangari, Frits van Rhee, Tariq Mughal, Faith E Davies, Brian A Walker
Leukemia. 2018; 32(11): 2435–2444. Published online 2018 Mar 23. doi: 10.1038/s41375-018-0108-y
PMCID:
PMC6224403
AbstractArticlePDF–1.5M

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