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Items: 1 to 20 of 26

1.
SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion
Zheng Chen, Mincheng Yu, Bo Zhang, Lei Jin, Qiang Yu, Shuang Liu, Binghai Zhou, Jiuliang Yan, Wentao Zhang, Xiaoqiang Li, Yongfeng Xu, Yongsheng Xiao, Jian Zhou, Jia Fan, Mien-Chie Hung, Qinghai Ye, Hui Li, Lei Guo
Oncoimmunology. 2024; 13(1): 2376264. Published online 2024 Jul 9. doi: 10.1080/2162402X.2024.2376264
PMCID:
PMC11236293
AbstractArticlePDF–5.3M
2.
Siglec-15 on macrophages suppress the immune microenvironment in patients with PD-L1 negative non-metastasis lung adenocarcinoma
Ziqi Huang, Yan Guo, Baihui Li, Meng Shen, Yeran Yi, Li Li, Xiaohe Zhao, Lili Yang
Cancer Gene Ther. 2024; 31(3): 427–438. Published online 2023 Dec 11. doi: 10.1038/s41417-023-00713-z
PMCID:
PMC10940158
AbstractArticlePDF–4.9M
3.
Non-spatial and spatial heterogeneity revealed a suppressive immune feature of Siglec-15 in lung adenocarcinomas
Baihui Li, Yan Guo, Yeran Yi, Ziqi Huang, Yulin Ren, Hao Wang, Lili Yang
J Transl Med. 2023; 21: 599. Published online 2023 Sep 6. doi: 10.1186/s12967-023-04489-6
PMCID:
PMC10483852
AbstractArticlePDF–6.8M
4.
Siglec-15 Promotes Evasion of Adaptive Immunity in B-cell Acute Lymphoblastic Leukemia
Claire E. Pillsbury, Jodi Dougan, Jennifer L. Rabe, Jairo A. Fonseca, Chengjing Zhou, Alyssa N. Evans, Hasan Abukharma, Ona Ichoku, Gloria Gonzalez-Flamenco, Sunita I. Park, Ahmed Aljudi, Deborah DeRyckere, Sharon M. Castellino, Sarwish Rafiq, Solomon Langermann, Linda N. Liu, Curtis J. Henry, Christopher C. Porter
Cancer Res Commun. 2023 Jul; 3(7): 1248–1259. Published online 2023 Jul 17. doi: 10.1158/2767-9764.CRC-23-0056
PMCID:
PMC10351425
AbstractArticlePDF–4.4M
5.
Siglec15 is a prognostic indicator and a potential tumor-related macrophage regulator that is involved in the suppressive immunomicroenvironment in gliomas
Jinchao Wang, Linzong Xu, Qian Ding, Xiaoru Li, Kai Wang, Shangchen Xu, Bin Liu
Front Immunol. 2023; 14: 1065062. Published online 2023 May 30. doi: 10.3389/fimmu.2023.1065062
PMCID:
PMC10266207
AbstractArticlePDF–9.5M
6.
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
Maria Pia Lenza, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Cátia O. Soares, Helena Coelho, Francisco Corzana, Alexandre Bosch, Prodhi Manisha, Jon Imanol Quintana, Iker Oyenarte, Luca Unione, María Jesús Moure, Mikel Azkargorta, Unai Atxabal, Klaudia Sobczak, Felix Elortza, James D. Sutherland, Rosa Barrio, Filipa Marcelo, Jesús Jiménez-Barbero, Asis Palazon, June Ereño-Orbea
Nat Commun. 2023; 14: 3496. Published online 2023 Jun 13. doi: 10.1038/s41467-023-39119-8
PMCID:
PMC10264397
AbstractArticlePDF–3.6M
7.
Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma
Quan Chen, Bingkun Chen, Chunhua Wang, Li Hu, Qiongwen Wu, Yanyang Zhu, Qiuyu Zhang
Front Immunol. 2023; 14: 1159085. Published online 2023 May 10. doi: 10.3389/fimmu.2023.1159085
PMCID:
PMC10206144
AbstractArticlePDF–12M
8.
Significance of Siglec‐15 expression in colorectal cancer: association with advanced disease stage and fewer tumor‐infiltrating lymphocytes
Zhao Lu, Pu Cheng, Fei Huang, Jiyun Li, Bingzhi Wang, Shuangmei Zou, Zhaoxu Zheng, Chunwei Peng
J Pathol Clin Res. 2023 Mar; 9(2): 121–128. Published online 2022 Nov 24. doi: 10.1002/cjp2.303
PMCID:
PMC9896156
AbstractArticlePDF–889K
9.
Transcriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma Cells
Kaiqin Sheng, Yuecheng Wu, Hanbin Lin, Menghan Fang, Chaorong Xue, Xu Lin, Xinjian Lin
Int J Mol Sci. 2023 Jan; 24(1): 792. Published online 2023 Jan 2. doi: 10.3390/ijms24010792
PMCID:
PMC9821606
AbstractArticlePDF–3.5M
10.
Expression and function of Siglec-15 in RLPS and its correlation with PD-L1: Bioinformatics Analysis and Clinicopathological Evidence
Lixuan Cui, Xiuyun Tian, Liang Yan, Xiaoya Guan, Bin Dong, Min Zhao, Ang Lv, Daoning Liu, Jianhui Wu, Chunyi Hao
Int J Med Sci. 2022; 19(13): 1977–1988. Published online 2022 Oct 31. doi: 10.7150/ijms.77193
PMCID:
PMC9682511
AbstractArticlePDF–1.6M
11.
Siglec-15 as a New Perspective Therapy Target in Human Giant Cell Tumor of Bone
Mengke Fan, Guochuan Zhang, Mingfang Xie, Xinbo Liu, Qi Zhang, Ling Wang
Curr Oncol. 2022 Oct; 29(10): 7655–7671. Published online 2022 Oct 13. doi: 10.3390/curroncol29100605
PMCID:
PMC9600077
AbstractArticlePDF–3.8M
12.
Unveiling the molecular features, relevant immune and clinical characteristics of SIGLEC15 in thyroid cancer
Xiaofeng Hou, Chao Chen, Xiabin Lan, Xiaodong He
Front Immunol. 2022; 13: 975787. Published online 2022 Sep 9. doi: 10.3389/fimmu.2022.975787
PMCID:
PMC9500188
AbstractArticlePDF–24M
13.
Siglec-15 Silencing Inhibits Cell Proliferation and Promotes Cell Apoptosis by Inhibiting STAT1/STAT3 Signaling in Anaplastic Thyroid Carcinoma
Xiaofeng Hou, Chao Chen, Xiaodong He, Xiabin Lan
Dis Markers. 2022; 2022: 1606404. Published online 2022 Jun 20. doi: 10.1155/2022/1606404
PMCID:
PMC9236774
AbstractArticlePDF–3.4M
14.
Prognostic value of PD-L1 and Siglec-15 expression in patients with nasopharyngeal carcinoma
Ju Zhao, Hanshan Yang, Hui Hu, Chao Liu, Min Wei, Yumei Zhao, Yudan Chen, Yongxia Cui, Ping Chen, Kang Xiong, Yun Lu, Hongru Yang, Linglin Yang
Sci Rep. 2022; 12: 10401. Published online 2022 Jun 21. doi: 10.1038/s41598-022-13997-2
PMCID:
PMC9213533
AbstractArticlePDF–1.2M
15.
Analysis of a novel immune checkpoint, Siglec‐15, in pancreatic ductal adenocarcinoma
Xianlong Chen, Shengwei Mo, Yue Zhang, Heng Ma, Zhaohui Lu, Shuangni Yu, Jie Chen
J Pathol Clin Res. 2022 May; 8(3): 268–278. Published online 2022 Jan 27. doi: 10.1002/cjp2.260
PMCID:
PMC8977273
AbstractArticlePDF–3.9M
16.
Long Noncoding RNA TUG1 Inhibits Tumor Progression through Regulating Siglec-15-Related Anti-Immune Activity in Hepatocellular Carcinoma
Yanyi Ren, Jiayi Lyu, Yaoguang Guo, Yuan Yao, Lin Hu
J Immunol Res. 2022; 2022: 9557859. Published online 2022 Feb 21. doi: 10.1155/2022/9557859
PMCID:
PMC8885264
AbstractArticlePDF–5.3M
17.
Siglec-15 promotes progression of clear renal cell carcinoma
Wen-Bo Yang, Cai-Peng Qin, Yi-Qing Du, Song-Chen Han, Tao Xu
Chin Med J (Engl) 2021 Nov 5; 134(21): 2635–2637. Published online 2021 Sep 22. doi: 10.1097/CM9.0000000000001752
PMCID:
PMC8577683
ArticlePDF–179K
18.
Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters
Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mário S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo
Eur J Histochem. 2021 Jan 20; 65(1): 3174. Published online 2021 Mar 4. doi: 10.4081/ejh.2021.3174
PMCID:
PMC7967265
AbstractArticlePDF–1.2M
19.
Siglec15 shapes a non-inflamed tumor microenvironment and predicts the molecular subtype in bladder cancer
Jiao Hu, Anze Yu, Belaydi Othmane, Dongxu Qiu, Huihuang Li, Chao Li, Peihua Liu, Wenbiao Ren, Minfeng Chen, Guanghui Gong, Xi Guo, Huihui Zhang, Jinbo Chen, Xiongbing Zu
Theranostics. 2021; 11(7): 3089–3108. Published online 2021 Jan 1. doi: 10.7150/thno.53649
PMCID:
PMC7847675
AbstractArticlePDF–6.3M
20.
Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients
Hirotaka Fudaba, Yasutomo Momii, Taisei Hirakawa, Kouhei Onishi, Daigo Asou, Wataru Matsushita, Yukari Kawasaki, Kenji Sugita, Minoru Fujiki
Sci Rep. 2021; 11: 1206. Published online 2021 Jan 13. doi: 10.1038/s41598-020-79742-9
PMCID:
PMC7806611
AbstractArticlePDF–1.5M

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