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Items: 18

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
MicroRNA-561 Affects Proliferation and Cell Cycle Transition Through PTEN/AKT Signaling Pathway by Targeting P-REX2a in NSCLC
ZiJun Liao, Qi Zheng, Ting Wei, YanBing Zhang, JieQun Ma, Zheng Zhao, HaiFeng Sun, KeJun Nan
Oncol Res. 2020; 28(2): 147–159. Published online 2020 Mar 27. doi: 10.3727/096504019X15732109856009
PMCID:
PMC7851535
AbstractArticlePDF–7.7M
3.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
4.
CELF2 suppresses non-small cell lung carcinoma growth by inhibiting the PREX2-PTEN interaction
Yiu To Yeung, Suyu Fan, Bingbing Lu, Shuying Yin, Sen Yang, Wenna Nie, Meixian Wang, Liting Zhou, Tiepeng Li, Xiang Li, Ann M Bode, Zigang Dong
Carcinogenesis. 2020 May; 41(3): 377–389. Published online 2019 Jun 25. doi: 10.1093/carcin/bgz113
PMCID:
PMC7221505
AbstractArticlePDF–13M
5.
Somatic mutations of PREX2 gene in patients with hepatocellular carcinoma
Ming-Hui Yang, Chia-Hung Yen, Yen-Fu Chen, Cheng-Chieh Fang, Chung-Hsien Li, Kuo-Jui Lee, Yi-Hsiung Lin, Chien-Hui Weng, Tze-Tze Liu, Shiu-Feng Huang, Bin Tean Teh, Yi-Ming Arthur Chen
Sci Rep. 2019; 9: 2552. Published online 2019 Feb 22. doi: 10.1038/s41598-018-36810-5
PMCID:
PMC6385191
AbstractArticlePDF–1.7M
6.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
7.
Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations
Stephen K Horrigan, Pascal Courville, Darryl Sampey, Faren Zhou, Steve Cai, Reproducibility Project: Cancer Biology
eLife. 2017; 6: e21634. Published online 2017 Jan 19. doi: 10.7554/eLife.21634
PMCID:
PMC5245968
AbstractArticlePDF–1.1M
8.
Melanoma mystery
Roger J Davis
eLife. 2017; 6: e22662. Published online 2017 Jan 19. doi: 10.7554/eLife.22662
PMCID:
PMC5245955
AbstractArticlePDF–489K
9.
Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma
Yonathan Lissanu Deribe
Small GTPases. 2016 Jul-Sep; 7(3): 178–185. Published online 2016 Apr 25. doi: 10.1080/21541248.2016.1178366
PMCID:
PMC5003543
AbstractArticlePDF–760K
10.
PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion
Sarah M. Mense, Douglas Barrows, Cindy Hodakoski, Nicole Steinbach, David Schoenfeld, William Su, Benjamin D. Hopkins, Tao Su, Barry Fine, Hanina Hibshoosh, Ramon Parsons
Sci Signal. Author manuscript; available in PMC 2016 May 31.
Published in final edited form as: Sci Signal. 2015 Mar 31; 8(370): ra32. Published online 2015 Mar 31. doi: 10.1126/scisignal.2005840
PMCID:
PMC4874664
AbstractArticlePDF–2.7M
11.
Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma
Yonathan Lissanu Deribe, Yanxia Shi, Kunal Rai, Luigi Nezi, Samir B. Amin, Chia-Chin Wu, Kadir C. Akdemir, Mozhdeh Mahdavi, Qian Peng, Qing Edward Chang, Kirsti Hornigold, Stefan T. Arold, Heidi C. E. Welch, Levi A. Garraway, Lynda Chin
Proc Natl Acad Sci U S A. 2016 Mar 1; 113(9): E1296–E1305. Published online 2016 Feb 16. doi: 10.1073/pnas.1513801113
PMCID:
PMC4780599
AbstractArticlePDF–2.0M
12.
p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase
Douglas Barrows, Sarah M. Schoenfeld, Cindy Hodakoski, Antonina Silkov, Barry Honig, Anthony Couvillon, Aliaksei Shymanets, Bernd Nürnberg, John M. Asara, Ramon Parsons
J Biol Chem. 2015 Nov 27; 290(48): 28915–28931. Published online 2015 Oct 5. doi: 10.1074/jbc.M115.668244
PMCID:
PMC4661405
AbstractArticlePDF–2.8M
13.
Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis
Cindy Hodakoski, Benjamin D. Hopkins, Douglas Barrows, Sarah M. Mense, Megan Keniry, Karen E. Anderson, Philip A. Kern, Phillip T. Hawkins, Len R. Stephens, Ramon Parsons
Proc Natl Acad Sci U S A. 2014 Jan 7; 111(1): 155–160. Published online 2013 Dec 23. doi: 10.1073/pnas.1213773111
PMCID:
PMC3890808
AbstractArticlePDF–1.0M
14.
Melanoma genome sequencing reveals frequent PREX2 mutations
Michael F. Berger, Eran Hodis, Timothy P. Heffernan, Yonathan Lissanu Deribe, Michael S. Lawrence, Alexei Protopopov, Elena Ivanova, Ian R. Watson, Elizabeth Nickerson, Papia Ghosh, Hailei Zhang, Rhamy Zeid, Xiaojia Ren, Kristian Cibulskis, Andrey Y. Sivachenko, Nikhil Wagle, Antje Sucker, Carrie Sougnez, Robert Onofrio, Lauren Ambrogio, Daniel Auclair, Timothy Fennell, Scott L. Carter, Yotam Drier, Petar Stojanov, Meredith A. Singer, Douglas Voet, Rui Jing, Gordon Saksena, Jordi Barretina, Alex H. Ramos, Trevor J. Pugh, Nicolas Stransky, Melissa Parkin, Wendy Winckler, Scott Mahan, Kristin Ardlie, Jennifer Baldwin, Jennifer Wargo, Dirk Schadendorf, Matthew Meyerson, Stacey B. Gabriel, Todd R. Golub, Stephan N. Wagner, Eric S. Lander, Gad Getz, Lynda Chin, Levi A. Garraway
Nature. Author manuscript; available in PMC 2012 Nov 24.
Published in final edited form as: Nature. 2012 May 24; 485(7399): 502–506. Published online 2012 May 9. doi: 10.1038/nature11071
PMCID:
PMC3367798
AbstractArticlePDF–567K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Activation of the PI3K Pathway in Cancer through Inhibition of PTEN by Exchange Factor P-REX2a
Barry Fine, Cindy Hodakoski, Susan Koujak, Tao Su, Lao H. Saal, Matthew Maurer, Benjamin Hopkins, Megan Keniry, Maria Luisa Sulis, Sarah Mense, Hanina Hibshoosh, Ramon Parsons
Science. Author manuscript; available in PMC 2010 Sep 10.
Published in final edited form as: Science. 2009 Sep 4; 325(5945): 1261–1265. doi: 10.1126/science.1173569
PMCID:
PMC2936784
AbstractArticlePDF–1.7M
17.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
18.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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