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Items: 1 to 20 of 38

1.
IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses
Shuai Shao, Lam C. Tsoi, William R. Swindell, Jiaoling Chen, Ranjitha Uppala, Allison C. Billi, Xianying Xing, Chang Zeng, Mrinal K. Sarkar, Rachael Wasikowski, Yanyun Jiang, Joseph Kirma, Jingru Sun, Olesya Plazyo, Gang Wang, Paul W. Harms, John J. Voorhees, Nicole L. Ward, Feiyang Ma, Matteo Pellegrini, Alexander Merleev, Bethany E. Perez White, Robert L. Modlin, Bogi Andersen, Emanual Maverakis, Stephan Weidinger, J. Michelle Kahlenberg, Johann E. Gudjonsson
J Invest Dermatol. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: J Invest Dermatol. 2021 Oct; 141(10): 2436–2448. Published online 2021 Apr 15. doi: 10.1016/j.jid.2021.03.019
PMCID:
PMC9423738
AbstractArticlePDF–2.5M
2.
Multi-locus SNP analyses of interleukin 1 receptor associated kinases 2 gene polymorphisms with the susceptibility to rheumatoid arthritis
Maham Ghouri, Muhammad Ismail, Syeda Areesha Zaidi, Shafique Rehman, Asadullah Dahani, Saima Saleem, Sitwat Zehra
PLoS One. 2022; 17(5): e0268496. Published online 2022 May 19. doi: 10.1371/journal.pone.0268496
PMCID:
PMC9119434
AbstractArticlePDF–877K
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Epigenetic silencing of microRNA-373 to epithelial-mesenchymal transition in non-small cell lung cancer through IRAK2 and LAMP1 axes
Hyang Sook Seol, Yoshimitsu Akiyama, Shu Shimada, Hee Jin Lee, Tae Im Kim, Sung Min Chun, Shree Ram Singh, Se Jin Jang
Cancer Lett. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Cancer Lett. 2014 Oct 28; 353(2): 232–241. Published online 2014 Jul 22. doi: 10.1016/j.canlet.2014.07.019
PMCID:
PMC7707239
AbstractArticlePDF–1.7M
5.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
6.
MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling
Martin C. Moncrieffe, Daniel Bollschweiler, Bing Li, Pawel A. Penczek, Lee Hopkins, Clare E. Bryant, David Klenerman, Nicholas J. Gay
Structure. 2020 Mar 3; 28(3): 281–289.e3. doi: 10.1016/j.str.2020.01.003
PMCID:
PMC7054835
AbstractArticle
7.
RNF152 positively regulates TLR/IL‐1R signaling by enhancing MyD88 oligomerization
Mei‐Guang Xiong, Zhi‐Sheng Xu, Yu‐Hui Li, Su‐Yun Wang, Yan‐Yi Wang, Yong Ran
EMBO Rep. 2020 Mar 4; 21(3): e48860. Published online 2020 Jan 13. doi: 10.15252/embr.201948860
PMCID:
PMC7054668
AbstractArticlePDF–1.2M
8.
Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer
Yinghui Xu, Hongliang Liu, Shun Liu, Yanru Wang, Jichun Xie, Thomas E. Stinchcombe, Li Su, Ruyang Zhang, David C. Christiani, Wei Li, Qingyi Wei
Int J Cancer. Author manuscript; available in PMC 2019 Nov 15.
Published in final edited form as: Int J Cancer. 2018 Nov 15; 143(10): 2400–2408. Published online 2018 Sep 21. doi: 10.1002/ijc.31660
PMCID:
PMC6205899
AbstractArticlePDF–525K
9.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
A Coding IRAK2 Protein Variant Compromises Toll-like receptor (TLR) Signaling and Is Associated with Colorectal Cancer Survival
Hui Wang, Sinead M. Flannery, Sabine Dickhöfer, Stefanie Huhn, Julie George, Andriy V. Kubarenko, Jesus Lascorz, Melanie Bevier, Joschka Willemsen, Tica Pichulik, Clemens Schafmayer, Marco Binder, Bénédicte Manoury, Søren R. Paludan, Marta Alarcon-Riquelme, Andrew G. Bowie, Asta Försti, Alexander N. R. Weber
J Biol Chem. 2014 Aug 15; 289(33): 23123–23131. Published online 2014 Jun 19. doi: 10.1074/jbc.M113.492934
PMCID:
PMC4132810
AbstractArticlePDF–906K
12.
Interleukin-1 Receptor-associated Kinase-2 Genetic Variant rs708035 Increases NF-κB Activity through Promoting TRAF6 Ubiquitination
Weina Zhang, Tao He, Qiong Wang, Xin Li, Jianming Wei, Xiaoqiang Hou, Bin Zhang, Lei Huang, Li Wang
J Biol Chem. 2014 May 2; 289(18): 12507–12519. Published online 2014 Mar 24. doi: 10.1074/jbc.M113.538009
PMCID:
PMC4007444
AbstractArticlePDF–2.7M
13.
The Tumor Necrosis Family Member 4-1BBL Sustains Inflammation by Interacting with Mediators of Toll-Like Receptor Signaling
Jianhui Ma, Bo-Ram Bang, Jiawei Lu, So-Young Eun, Motoyuki Otsuka, Michael Croft, Peter Tobias, Jiahuai Han, Osamu Takeuchi, Shizuo Akira, Michael Karin, Hideo Yagita, Young Jun Kang
Sci Signal. Author manuscript; available in PMC 2014 Apr 29.
Published in final edited form as: Sci Signal. 2013 Oct 1; 6(295): ra87. Published online 2013 Oct 1. doi: 10.1126/scisignal.2004431
PMCID:
PMC4004444
AbstractArticlePDF–1.4M
14.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M
15.
HIV-1 gp120 impairs B cell proliferation by inducing TGF-ß1 production and FcRL4 expression
Katija Jelicic, Raffaello Cimbro, Fatima Nawaz, Da Wei Huang, Xin Zheng, Jun Yang, Richard A. Lempicki, Massimiliano Pascuccio, Donald Van Ryk, Catherine Schwing, Joseph Hiatt, Noreen Okwara, Danlan Wei, Gregg Roby, Antonio David, Young Hwang, II, John H. Kehrl, James Arthos, Claudia Cicala, Anthony S. Fauci
Nat Immunol. Author manuscript; available in PMC 2014 Jun 1.
Published in final edited form as: Nat Immunol. 2013 Dec; 14(12): 1256–1265. Published online 2013 Oct 27. doi: 10.1038/ni.2746
PMCID:
PMC3870659
AbstractArticlePDF–1.4M
16.
Interleukin-1 Receptor-Associated Kinase-2 (IRAK2) Is a Critical Mediator of Endoplasmic Reticulum (ER) Stress Signaling
Samir Benosman, Palaniyandi Ravanan, Ricardo G. Correa, Ying-Chen Hou, Minjia Yu, Muhammet Fatih Gulen, Xiaoxia Li, James Thomas, Michael Cuddy, Yasuko Matsuzawa, Renata Sano, Paul Diaz, Shu-ichi Matsuzawa, John C. Reed
PLoS One. 2013; 8(5): e64256. Published online 2013 May 28. doi: 10.1371/journal.pone.0064256
PMCID:
PMC3665826
AbstractArticlePDF–1.7M
17.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M
18.
Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production
Shitao Li, Lingyan Wang, Michael Berman, Young-Yun Kong, Martin E. Dorf
Immunity. Author manuscript; available in PMC 2012 Sep 23.
Published in final edited form as: Immunity. 2011 Sep 23; 35(3): 426–440. Published online 2011 Sep 8. doi: 10.1016/j.immuni.2011.06.014
Correction in:
volume 35 on page 647
PMCID:
PMC3253658
AbstractArticlePDF–4.2M
19.
A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease
Jingran Zhou, Ruiqiong Wu, Anthony A. High, Clive A. Slaughter, David Finkelstein, Jerold E. Rehg, Vanessa Redecke, Hans Häcker
Proc Natl Acad Sci U S A. 2011 Nov 1; 108(44): E998–E1006. Published online 2011 Oct 19. doi: 10.1073/pnas.1106232108
PMCID:
PMC3207663
AbstractArticlePDF–1.5M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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