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Select item 103826021.

NOVA1 acts on Impact to regulate hypothalamic function and translation in inhibitory neurons

Yoko Tajima, Keiichi Ito, Yuan Yuan, Mayu O. Frank, Yuhki Saito, Robert B. Darnell

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112050. Published online 2023 Jan 29. doi: 10.1016/j.celrep.2023.112050

PMCID:: PMC10382602

Abstract Article PDF–2.5M

Select item 95008912.

Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice

Manoja K. Brahma, Peng Xiao, Madalina Popa, Javier Negueruela, Valerie Vandenbempt, Stéphane Demine, Alessandra K. Cardozo, Esteban N. Gurzov

Nutrients. 2022 Sep; 14(18): 3866. Published online 2022 Sep 18. doi: 10.3390/nu14183866

PMCID:: PMC9500891

Abstract Article PDF–3.7M

Select item 93814483.

Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis

Florian Krach, Emily C. Wheeler, Martin Regensburger, Tom Boerstler, Holger Wend, Anthony Q. Vu, Ruth Wang, Stephanie Reischl, Karsten Boldt, Ranjan Batra, Stefan Aigner, John Ravits, Juergen Winkler, Gene W. Yeo, Beate Winner

Acta Neuropathol. 2022; 144(3): 413–435. Published online 2022 Jul 1. doi: 10.1007/s00401-022-02450-3

PMCID:: PMC9381448

Abstract Article PDF–7.7M

Select item 91619564.

MicroRNA miR-27a-3p accelerates cardiac hypertrophy by targeting neuro-oncological ventral antigen 1

Dongyun Li, Mingzhi Shen, Xinxin Deng, Yongyi Bai

Bioengineered. 2022; 13(4): 8982–8993. Published online 2022 Mar 29. doi: 10.1080/21655979.2022.2054150

PMCID:: PMC9161956

Abstract Article PDF–2.6M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66873906.

Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2

Verity Johnson, Harald J Junge, Zhe Chen

eLife. 2019; 8: e46042. Published online 2019 Aug 8. doi: 10.7554/eLife.46042

PMCID:: PMC6687390

Abstract Article PDF–3.7M

Select item 65787957.

The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies

RJ Buckanovich, YY Yang, RB Darnell

J Neurosci. 1996 Feb 1; 16(3): 1114–1122. doi: 10.1523/JNEUROSCI.16-03-01114.1996

PMCID:: PMC6578795

Abstract PDF–3.8M

Select item 60927978.

Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons

Yuan Yuan, Shirley Xie, Jennifer C. Darnell, Andrew J. Darnell, Yuhki Saito, Hemali Phatnani, Elisabeth A. Murphy, Chaolin Zhang, Tom Maniatis, Robert B. Darnell

Genome Biol. 2018; 19: 117. Published online 2018 Aug 15. doi: 10.1186/s13059-018-1493-2

PMCID:: PMC6092797

Abstract Article PDF–2.4M

Select item 59892659.

Precise temporal regulation of alternative splicing during neural development

Sebastien M. Weyn-Vanhentenryck, Huijuan Feng, Dmytro Ustianenko, Rachel Duffié, Qinghong Yan, Martin Jacko, Jose C. Martinez, Marianne Goodwin, Xuegong Zhang, Ulrich Hengst, Stavros Lomvardas, Maurice S. Swanson, Chaolin Zhang

Nat Commun. 2018; 9: 2189. Published online 2018 Jun 6. doi: 10.1038/s41467-018-04559-0

PMCID:: PMC5989265

Abstract Article PDF–2.6M

Select item 586818110.

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Jin Li, Su-Ping Deng, Gang Wei, Peng Yu

Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012

PMCID:: PMC5868181

Abstract Article PDF–653K

Select item 511483911.

Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat

Miyako Suzuki, Misato Kobayashi, Tamio Ohno, Shinsaku Kanamori, Soushi Tateishi, Atsushi Murai, Fumihiko Horio

BMC Genet. 2016; 17: 145. Published online 2016 Nov 17. doi: 10.1186/s12863-016-0453-7

PMCID:: PMC5114839

Abstract Article PDF–1.1M

Select item 502647212.

An alternative splicing program promotes adipose tissue thermogenesis

Santiago Vernia, Yvonne JK Edwards, Myoung Sook Han, Julie Cavanagh-Kyros, Tamera Barrett, Jason K Kim, Roger J Davis

eLife. 2016; 5: e17672. Published online 2016 Sep 16. doi: 10.7554/eLife.17672

PMCID:: PMC5026472

Abstract Article PDF–3.1M

Select item 493597413.

Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses

Katannya Kapeli, Gabriel A. Pratt, Anthony Q. Vu, Kasey R. Hutt, Fernando J. Martinez, Balaji Sundararaman, Ranjan Batra, Peter Freese, Nicole J. Lambert, Stephanie C. Huelga, Seung J. Chun, Tiffany Y. Liang, Jeremy Chang, John P. Donohue, Lily Shiue, Jiayu Zhang, Haining Zhu, Franca Cambi, Edward Kasarskis, Shawn Hoon, Manuel Ares Jr., Christopher B. Burge, John Ravits, Frank Rigo, Gene W. Yeo

Nat Commun. 2016; 7: 12143. Published online 2016 Jul 5. doi: 10.1038/ncomms12143

PMCID:: PMC4935974

Abstract Article PDF–1.7M

Select item 493032914.

NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord

Janelle C Leggere, Yuhki Saito, Robert B Darnell, Marc Tessier-Lavigne, Harald J Junge, Zhe Chen

eLife. 2016; 5: e14264. Published online 2016 May 25. doi: 10.7554/eLife.14264

PMCID:: PMC4930329

Abstract Article PDF–8.3M

Select item 493032815.

NOVA2-mediated RNA regulation is required for axonal pathfinding during development

Yuhki Saito, Soledad Miranda-Rottmann, Matteo Ruggiu, Christopher Y Park, John J Fak, Ru Zhong, Jeremy S Duncan, Brian A Fabella, Harald J Junge, Zhe Chen, Roberto Araya, Bernd Fritzsch, A J Hudspeth, Robert B Darnell

eLife. 2016; 5: e14371. Published online 2016 May 25. doi: 10.7554/eLife.14371

PMCID:: PMC4930328

Abstract Article PDF–6.2M

Select item 474662516.

RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes

Jung-Chun Lin, Yi-Han Lu, Yun-Ru Liu, Ying-Ju Lin

Sci Rep. 2016; 6: 20665. Published online 2016 Feb 9. doi: 10.1038/srep20665

PMCID:: PMC4746625

Abstract Article PDF–2.0M

Select item 463371917.

The alternative splicing factor Nova2 regulates vascular development and lumen formation

Costanza Giampietro, Gianluca Deflorian, Stefania Gallo, Anna Di Matteo, Davide Pradella, Serena Bonomi, Elisa Belloni, Daniel Nyqvist, Valeria Quaranta, Stefano Confalonieri, Giovanni Bertalot, Fabrizio Orsenigo, Federica Pisati, Elisabetta Ferrero, Giuseppe Biamonti, Evelien Fredrickx, Carla Taveggia, Chris D. R. Wyatt, Manuel Irimia, Pier Paolo Di Fiore, Benjamin J. Blencowe, Elisabetta Dejana, Claudia Ghigna

Nat Commun. 2015; 6: 8479. Published online 2015 Oct 8. doi: 10.1038/ncomms9479

PMCID:: PMC4633719

Abstract Article PDF–3.4M

Select item 406776918.

A genomic atlas of mouse hypothalamic development

Tomomi Shimogori, Daniel A Lee, Ana Miranda-Angulo, Yanqin Yang, Hong Wang, Lizhi Jiang, Aya C Yoshida, Ayane Kataoka, Hiromi Mashiko, Marina Avetisyan, Lixin Qi, Jiang Qian, Seth Blackshaw

Nat Neurosci. Author manuscript; available in PMC 2014 Jun 24.

Published in final edited form as: Nat Neurosci. 2010 Jun; 13(6): 767–775. Published online 2010 May 2. doi: 10.1038/nn.2545

PMCID:: PMC4067769

Abstract Article PDF–1.8M

Select item 355242419.

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure

Taesun Eom, Chaolin Zhang, Huidong Wang, Kenneth Lay, John Fak, Jeffrey L Noebels, Robert B Darnell

eLife. 2013; 2: e00178. Published online 2013 Jan 22. doi: 10.7554/eLife.00178

PMCID:: PMC3552424

Abstract Article PDF–5.5M

Select item 341241020.

Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls

Chaolin Zhang, Maria A. Frias, Aldo Mele, Matteo Ruggiu, Taesun Eom, Christina B. Marney, Huidong Wang, Donny D. Licatalosi, John J. Fak, Robert B. Darnell

Science. Author manuscript; available in PMC 2012 Aug 6.

Published in final edited form as: Science. 2010 Jul 23; 329(5990): 439–443. Published online 2010 Jun 17. doi: 10.1126/science.1191150

PMCID:: PMC3412410

Abstract Article PDF–2.3M

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