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Select item 108280651.

Identification of a buried β-strand as a novel disease-related motif in the human polysialyltransferases

Rina Hatanaka, Masaya Hane, Kaito Hayakawa, Sayo Morishita, Shiho Ohno, Yoshiki Yamaguchi, Di Wu, Ken Kitajima, Chihiro Sato

J Biol Chem. 2024 Jan; 300(1): 105564. Published online 2023 Dec 14. doi: 10.1016/j.jbc.2023.105564

PMCID:: PMC10828065

Abstract Article PDF–3.1M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80948023.

N‐CAM Dysfunction and Unexpected Accumulation of PSA‐NCAM in Brain of Adult‐Onset Autosomal‐Dominant Leukodystrophy

Marco Piccinini, Barbara Buccinnà, Giovanni De Marco, Elisa Lupino, Cristina Ramondetti, Silvia Grifoni, Barbara Votta, Maria Teresa Giordana, Maria Teresa Rinaudo

Brain Pathol. 2010 Mar; 20(2): 431–440. Published online 2009 Jun 25. doi: 10.1111/j.1750-3639.2009.00313.x

PMCID:: PMC8094802

Abstract Article PDF–397K

Select item 73220674.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 55773895.

The Polybasic Region of the Polysialyltransferase ST8Sia-IV Binds Directly to the Neural Cell Adhesion Molecule, NCAM

Gaurang P. Bhide, Gerd Prehna, Benjamin E. Ramirez, Karen J. Colley

Biochemistry. Author manuscript; available in PMC 2017 Aug 31.

Published in final edited form as: Biochemistry. 2017 Mar 14; 56(10): 1504–1517. Published online 2017 Mar 3. doi: 10.1021/acs.biochem.6b01221

PMCID:: PMC5577389

Abstract Article PDF–1.9M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54386287.

miR-146a and miR-146b promote proliferation, migration and invasion of follicular thyroid carcinoma via inhibition of ST8SIA4

Wei Ma, Xuzi Zhao, Leilei Liang, Guangzhi Wang, Yanyan Li, Xiaolong Miao, Yongfu Zhao

Oncotarget. 2017 Apr 25; 8(17): 28028–28041. Published online 2017 Mar 3. doi: 10.18632/oncotarget.15885

PMCID:: PMC5438628

Abstract Article PDF–15M

Select item 53123698.

Upregulation of miR-181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia

Lifen Zhao, Yan Li, Xiaobo Song, Huimin Zhou, Nana Li, Yuan Miao, Li Jia

Oncotarget. 2016 Sep 13; 7(37): 60074–60086. Published online 2016 Aug 4. doi: 10.18632/oncotarget.11054

PMCID:: PMC5312369

Abstract Article PDF–3.6M

Select item 52609769.

Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4

Xiaolu Ma, Weijie Dong, Zhen Su, Lifen Zhao, Yuan Miao, Nana Li, Huimin Zhou, Li Jia

Cell Death Dis. 2016 Dec; 7(12): e2561. Published online 2016 Dec 29. doi: 10.1038/cddis.2016.427

PMCID:: PMC5260976

Abstract Article PDF–5.0M

Select item 493198110.

ST8SIA4 dependent polysialylation is part of a developmental program required for germ layer formation from human pluripotent stem cells

Ryan P. Berger, Yu Hua Sun, Michael Kulik, Jin Kyu Lee, Alison V. Nairn, Kelley W. Moremen, Michael Pierce, Stephen Dalton

Stem Cells. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: Stem Cells. 2016 Jul; 34(7): 1742–1752. Published online 2016 May 3. doi: 10.1002/stem.2379

PMCID:: PMC4931981

Abstract Article PDF–1.1M

Select item 485028511.

Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans

Gaurang P. Bhide, Ninoshka R. J. Fernandes, Karen J. Colley

J Biol Chem. 2016 Apr 29; 291(18): 9444–9457. Published online 2016 Feb 16. doi: 10.1074/jbc.M116.714329

PMCID:: PMC4850285

Abstract Article PDF–1.7M

Select item 464794112.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 461721113.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 423033614.

Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection

Thor A. Wagner, Sherry McLaughlin, Kavita Garg, Charles Y. K. Cheung, Brendan B. Larsen, Sheila Styrchak, Hannah C. Huang, Paul T. Edlefsen, James I. Mullins, Lisa M. Frenkel

Science. Author manuscript; available in PMC 2014 Nov 13.

Published in final edited form as: Science. 2014 Aug 1; 345(6196): 570–573. Published online 2014 Jul 10. doi: 10.1126/science.1256304

PMCID:: PMC4230336

Abstract Article PDF–499K

Select item 374346715.

Polysialic Acid on Neuropilin-2 Is Exclusively Synthesized by the Polysialyltransferase ST8SiaIV and Attached to Mucin-type O-Glycans Located between the b2 and c Domain

Manuela Rollenhagen, Falk F. R. Buettner, Marc Reismann, Adan Chari Jirmo, Melanie Grove, Georg M. N. Behrens, Rita Gerardy-Schahn, Franz-Georg Hanisch, Martina Mühlenhoff

J Biol Chem. 2013 Aug 9; 288(32): 22880–22892. Published online 2013 Jun 25. doi: 10.1074/jbc.M113.463927

PMCID:: PMC3743467

Abstract Article PDF–1.7M

Select item 330732016.

Sequences Prior to Conserved Catalytic Motifs of Polysialyltransferase ST8Sia IV Are Required for Substrate Recognition

Joseph L. Zapater, Karen J. Colley

J Biol Chem. 2012 Feb 24; 287(9): 6441–6453. Published online 2011 Dec 19. doi: 10.1074/jbc.M111.322024

PMCID:: PMC3307320

Abstract Article PDF–1.8M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294516818.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 289646419.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 278318720.

The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations

Matthew P. Johnson, Linda T. Roten, Thomas D. Dyer, Christine E. East, Siri Forsmo, John Blangero, Shaun P. Brennecke, Rigmor Austgulen, Eric K. Moses

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2009 Nov; 126(5): 655–666. Published online 2009 Jul 4. doi: 10.1007/s00439-009-0714-x

PMCID:: PMC2783187

Abstract Article PDF–638K

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