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Items: 1 to 20 of 63

1.
A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB
Avraham Bayer, Stephanie J. Child, Harmit S. Malik, Adam P. Geballe
J Virol. 2023 Oct; 97(10): e00830-23. Published online 2023 Oct 5. doi: 10.1128/jvi.00830-23
PMCID:
PMC10617587
AbstractArticlePDF–1.6M
2.
Polymorphisms of the MxA and MxB genes are associated with biochemical indices and viral subtypes in Yunnan HCV patients
Mengzhu He, Min Liu, Jiawei Geng, Li Liu, Peng Huang, Ming Yue, Xueshan Xia, A-Mei Zhang
Front Cell Infect Microbiol. 2023; 13: 1119805. Published online 2023 Jan 19. doi: 10.3389/fcimb.2023.1119805
PMCID:
PMC9892934
AbstractArticlePDF–514K
3.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
4.
MX2: Identification and systematic mechanistic analysis of a novel immune-related biomarker for systemic lupus erythematosus
Xiang-Wen Meng, Zhi-Luo Cheng, Zhi-Yuan Lu, Ya-Nan Tan, Xiao-Yi Jia, Min Zhang
Front Immunol. 2022; 13: 978851. Published online 2022 Aug 18. doi: 10.3389/fimmu.2022.978851
PMCID:
PMC9433551
AbstractArticlePDF–8.4M
5.
Genetic polymorphisms in the IFNL4, MxA, and MxB genes were associated with biochemical index of chronic HBV patients from Yunnan, China
Kexi Zheng, Yunsong Shen, Xueshan Xia, Yuzhu Song, A-Mei Zhang
PeerJ. 2022; 10: e13353. Published online 2022 Apr 28. doi: 10.7717/peerj.13353
PMCID:
PMC9057288
AbstractArticlePDF–1.4M
6.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
7.
High accumulation of Mx2 renders limited multiplication of oncolytic herpes simplex virus-1 in human tumor cells
Yong Ren, Meiling Chen, Guangxian Wu, Dongmei Ji, Grace Guoying Zhou, Pei-Gen Ren, Wenmin Fu
Sci Rep. 2021; 11: 21227. Published online 2021 Oct 27. doi: 10.1038/s41598-021-00691-y
PMCID:
PMC8551283
AbstractArticlePDF–5.4M
8.
The transcriptome profile of human trisomy 21 blood cells
Francesca Antonaros, Rossella Zenatelli, Giulia Guerri, Matteo Bertelli, Chiara Locatelli, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri, Giuseppe Ramacieri, Guido Cocchi, Pierluigi Strippoli, Maria Caracausi, Allison Piovesan
Hum Genomics. 2021; 15: 25. Published online 2021 May 1. doi: 10.1186/s40246-021-00325-4
PMCID:
PMC8088681
AbstractArticlePDF–799K
9.
MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy
Marina Juraleviciute, Jérémie Nsengimana, Julia Newton‐Bishop, Gert J. Hendriks, Ana Slipicevic
Cancer Med. 2021 Apr; 10(8): 2840–2854. Published online 2021 Mar 18. doi: 10.1002/cam4.3846
PMCID:
PMC8026919
AbstractArticlePDF–2.5M
10.
MX2-mediated innate immunity against HIV-1 is regulated by serine phosphorylation
Gilberto Betancor, Jose M Jimenez-Guardeño, Steven Lynham, Robin Antrobus, Hataf Khan, Andrew Sobala, Matthew DJ Dicks, Michael H Malim
Nat Microbiol. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Nat Microbiol. 2021 Aug 1; 6(8): 1031–1042. Published online 2021 Jul 19. doi: 10.1038/s41564-021-00937-5
Correction in:
Nat Microbiol. 2021 Aug 13
PMCID:
PMC7611661
AbstractArticlePDF–3.5M
11.
HIV-1 resists MxB inhibition of viral Rev protein
Zhen Wang, Keli Chai, Qian Liu, Dong-Rong Yi, Qinghua Pan, Yu Huang, Juan Tan, Wentao Qiao, Fei Guo, Shan Cen, Chen Liang
Emerg Microbes Infect. 2020; 9(1): 2030–2045. Published online 2020 Sep 20. doi: 10.1080/22221751.2020.1818633
PMCID:
PMC7534208
AbstractArticlePDF–68M
12.
The GTPase Domain of MX2 Interacts with the HIV-1 Capsid, Enabling Its Short Isoform to Moderate Antiviral Restriction
Gilberto Betancor, Matthew D.J. Dicks, Jose M. Jimenez-Guardeño, Nabil H. Ali, Luis Apolonia, Michael H. Malim
Cell Rep. 2019 Nov 12; 29(7): 1923–1933.e3. Published online 2019 Nov 12. doi: 10.1016/j.celrep.2019.10.009
PMCID:
PMC7391006
AbstractArticle
13.
MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6
Linlin Xie, Lang Chen, Chaojie Zhong, Ting Yu, Zhao Ju, Meirong Wang, Hairong Xiong, Yan Zeng, Jianhua Wang, Haitao Hu, Wei Hou, Yong Feng
Retrovirology. 2020; 17: 16. Published online 2020 Jun 29. doi: 10.1186/s12977-020-00524-2
PMCID:
PMC7322711
AbstractArticlePDF–6.4M
14.
MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface
Richard J Miles, Claire Kerridge, Laura Hilditch, Christopher Monit, David A Jacques, Greg J Towers
eLife. 2020; 9: e56910. Published online 2020 Jun 17. doi: 10.7554/eLife.56910
PMCID:
PMC7299335
AbstractArticlePDF–2.9M
15.
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma
Jiyeon Choi, Tongwu Zhang, Andrew Vu, Julien Ablain, Matthew M. Makowski, Leandro M. Colli, Mai Xu, Rebecca C. Hennessey, Jinhu Yin, Harriet Rothschild, Cathrin Gräwe, Michael A. Kovacs, Karen M. Funderburk, Myriam Brossard, John Taylor, Bogdan Pasaniuc, Raj Chari, Stephen J. Chanock, Clive J. Hoggart, Florence Demenais, Jennifer H. Barrett, Matthew H. Law, Mark M. Iles, Kai Yu, Michiel Vermeulen, Leonard I. Zon, Kevin M. Brown
Nat Commun. 2020; 11: 2718. Published online 2020 Jun 1. doi: 10.1038/s41467-020-16590-1
PMCID:
PMC7264232
AbstractArticlePDF–1.9M
16.
Pro-515 of the dynamin-like GTPase MxB contributes to HIV-1 inhibition by regulating MxB oligomerization and binding to HIV-1 capsid
Fengwen Xu, Fei Zhao, Xiaoxiao Zhao, Di Zhang, Xiaoman Liu, Siqi Hu, Shan Mei, Zhangling Fan, Yu Huang, Hong Sun, Liang Wei, Chao Wu, Quanjie Li, Jianwei Wang, Shan Cen, Chen Liang, Fei Guo
J Biol Chem. 2020 May 8; 295(19): 6447–6456. Published online 2020 Mar 26. doi: 10.1074/jbc.RA119.012439
PMCID:
PMC7212661
AbstractArticlePDF–2.5M
17.
.MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid
Sarah Sierra Smaga, Chaoyi Xu, Brady James Summers, Katherine Marie Digianantonio, Juan R. Perilla, Yong Xiong
Structure. Author manuscript; available in PMC 2020 Apr 26.
Published in final edited form as: Structure. 2019 Aug 6; 27(8): 1234–1245.e5. Published online 2019 May 30. doi: 10.1016/j.str.2019.04.015
PMCID:
PMC7183857
AbstractArticlePDF–2.2M
18.
MX2 is a novel regulator of cell cycle in melanoma cells
Marina Juraleviciute, Joanna Pozniak, Jérémie Nsengimana, Mark Harland, Juliette Randerson-Moor, Patrik Vernhoff, Assia Bassarova, Geir Frode Øy, Gunhild Trøen, Vivi Ann Flørenes, David Timothy Bishop, Meenhard Herlyn, Julia Newton-Bishop, Ana Slipicevic
Pigment Cell Melanoma Res. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2020 May; 33(3): 446–457. Published online 2019 Nov 13. doi: 10.1111/pcmr.12837
Correction in:
Pigment Cell Melanoma Res. 2021 Sep; 34(5): 994.
PMCID:
PMC7180100
AbstractArticlePDF–1.8M
19.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
20.
The anti-viral dynamin family member MxB participates in mitochondrial integrity
Hong Cao, E. W. Krueger, Jing Chen, Kristina Drizyte-Miller, Mary E. Schulz, Mark A. McNiven
Nat Commun. 2020; 11: 1048. Published online 2020 Feb 26. doi: 10.1038/s41467-020-14727-w
PMCID:
PMC7044337
AbstractArticlePDF–11M

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