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Select item 112912711.

Induced CD8α identifies human NK cells with enhanced proliferative fitness and modulates NK cell activation

Celia C. Cubitt, Pamela Wong, Hannah K. Dorando, Jennifer A. Foltz, Jennifer Tran, Lynne Marsala, Nancy D. Marin, Mark Foster, Timothy Schappe, Hijab Fatima, Michelle Becker-Hapak, Alice Y. Zhou, Kimberly Hwang, Miriam T. Jacobs, David A. Russler-Germain, Emily M. Mace, Melissa M. Berrien-Elliott, Jacqueline E. Payton, Todd A. Fehniger

J Clin Invest. 2024 Aug 1; 134(15): e173602. Published online 2024 May 28. doi: 10.1172/JCI173602

PMCID:: PMC11291271

Abstract Article PDF–5.6M

Select item 112909602.

Striking a balance: the Goldilocks effect of CD8α expression on NK cells

Paarth B. Dodhiawala, Frank Cichocki

J Clin Invest. 2024 Aug 1; 134(15): e182905. Published online 2024 Aug 1. doi: 10.1172/JCI182905

PMCID:: PMC11290960

Abstract Article PDF–550K

Select item 108937003.

Genetic and pharmacologic p32-inhibition rescue CHCHD2-linked Parkinson’s disease phenotypes in vivo and in cell models

Murni Tio, Rujing Wen, Cai Ning Choo, Jian Bin Tan, Aaron Chua, Bin Xiao, Jeyapriya Rajameenakshi Sundaram, Christine Hui Shan Chan, Eng-King Tan

J Biomed Sci. 2024; 31: 24. Published online 2024 Feb 23. doi: 10.1186/s12929-024-01010-z

PMCID:: PMC10893700

Abstract Article PDF–14M

Select item 108654974.

Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma

Fereshteh Rezagholizadeh, Fatemeh Tajik, Morteza Talebi, Seyed Reza Taha, Mahdieh Shariat Zadeh, Pooya Farhangnia, Hamideh Sadat Hosseini, Aram Nazari, Shabnam Mollazadeh Ghomi, Seyede Mahtab Kamrani Mousavi, Niloofar Haeri Moghaddam, Hossein Khorramdelazad, Mohammad Taghi Joghataei, Elahe Safari

Front Immunol. 2024; 15: 1283364. Published online 2024 Jan 30. doi: 10.3389/fimmu.2024.1283364

PMCID:: PMC10865497

Abstract Article PDF–14M

Select item 108358645.

The relationship between high ratios of CD4/FOXP3 and CD8/CD163 and the improved survivability of metastatic triple-negative breast cancer patients: a multicenter cohort study

Jeffry Beta Tenggara, Andhika Rachman, Joedo Prihartono, Lisnawati Rachmadi, Sonar Soni Panigoro, Didik Setyo Heriyanto, Noorwati Sutandyo, Intan Russianna Nasution, Familia Bella Rahadiati, Ricci Steven, Rachelle Betsy, Samuel Juanputra, Aru Wisaksono Sudoyo

BMC Res Notes. 2024; 17: 44. Published online 2024 Feb 2. doi: 10.1186/s13104-024-06704-z

PMCID:: PMC10835864

Abstract Article PDF–1.0M

Select item 102278626.

Clonally-Expanded, Thyrotoxic Effector CD8⁺ T cells Driven by IL-21 Contribute to Checkpoint Inhibitor Thyroiditis

Melissa G. Lechner, Zikang Zhou, Aline T. Hoang, Nicole Huang, Jessica Ortega, Lauren N. Scott, Ho-Chung Chen, Anushi Y. Patel, Rana Yakhshi-Tafti, Kristy Kim, Willy Hugo, Pouyan Famini, Alexandra Drakaki, Antoni Ribas, Trevor E. Angell, Maureen A. Su

Sci Transl Med. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Sci Transl Med. 2023 May 17; 15(696): eadg0675. Published online 2023 May 17. doi: 10.1126/scitranslmed.adg0675

PMCID:: PMC10227862

Abstract Article PDF–2.1M

Select item 102056627.

Shaping immunity for life: layered development of CD8+ T cells

Cybelle Tabilas, Norah L. Smith, Dr. Brian D. Rudd

Immunol Rev. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Immunol Rev. 2023 May; 315(1): 108–125. Published online 2023 Jan 18. doi: 10.1111/imr.13185

PMCID:: PMC10205662

Abstract Article PDF–2.1M

Select item 101755448.

Interferon-gamma is quintessential for NOS2 and COX2 expression in ER^- breast tumors that lead to poor outcome

Robert Y. S. Cheng, Lisa A. Ridnour, Adelaide L. Wink, Ana L. Gonzalez, Elise L. Femino, Helene Rittscher, Veena Somasundaram, William F. Heinz, Leandro Coutinho, M. Cristina Rangel, Elijah F. Edmondson, Donna Butcher, Robert J. Kinders, Xiaoxian Li, Stephen T. C. Wong, Daniel W. McVicar, Stephen K. Anderson, Milind Pore, Stephen M. Hewitt, Timothy R. Billiar, Sharon A. Glynn, Jenny C. Chang, Stephen J. Lockett, Stefan Ambs, David A. Wink

Cell Death Dis. 2023 May; 14(5): 319. Published online 2023 May 11. doi: 10.1038/s41419-023-05834-9

PMCID:: PMC10175544

Abstract Article PDF–5.6M

Select item 101649609.

Kidney allograft rejection is associated with an imbalance of B cells, regulatory T cells and differentiated CD28-CD8+ T cells: analysis of a cohort of 1095 graft biopsies

Hoa Le Mai, Nicolas Degauque, Marine Lorent, Marie Rimbert, Karine Renaudin, Richard Danger, Clarisse Kerleau, Gaelle Tilly, Anaïs Vivet, Sabine Le Bot, Florent Delbos, Alexandre Walencik, Magali Giral, Sophie Brouard

Front Immunol. 2023; 14: 1151127. Published online 2023 Apr 24. doi: 10.3389/fimmu.2023.1151127

PMCID:: PMC10164960

Abstract Article PDF–410K

Select item 987019810.

Low on-treatment levels of serum soluble CD8 (sCD8) predict better outcomes in advanced non-small cell lung cancer patients treated with atezolizumab

Anna Siemiątkowska, Maciej Bryl, Katarzyna Kosicka-Noworzyń, Jakub Tvrdoň, Iwona Gołda-Gocka, Franciszek K. Główka

Cancer Immunol Immunother. 2023 Jun; 72(6): 1853–1863. Published online 2023 Jan 23. doi: 10.1007/s00262-023-03377-8

PMCID:: PMC9870198

Abstract Article PDF–1.3M

Select item 986195911.

Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases

Yiqiao Chen, Christopher E. M. Griffiths, Silvia Bulfone-Paus

Int J Mol Sci. 2023 Jan; 24(2): 1564. Published online 2023 Jan 13. doi: 10.3390/ijms24021564

PMCID:: PMC9861959

Abstract Article PDF–1.2M

Select item 968217912.

Granzyme B in circulating CD8+ T cells as a biomarker of immunotherapy effectiveness and disability in neuromyelitis optica spectrum disorders

Ziyan Shi, Qin Du, Xiaofei Wang, Jianchen Wang, Hongxi Chen, Yanling Lang, Lingyao Kong, Wenqin Luo, Mu Yang, Hongyu Zhou

Front Immunol. 2022; 13: 1027158. Published online 2022 Nov 9. doi: 10.3389/fimmu.2022.1027158

PMCID:: PMC9682179

Abstract Article PDF–2.4M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 745424014.

Brain metastasis PD-L1 and CD8 expression is dependent on primary tumor type and its PD-L1 and CD8 status

Florian Camy, Georgia Karpathiou, Jean Marc Dumollard, Nicolas Magne, Jean Luc Perrot, Francois Vassal, Tiphanie Picot, Mousa Mobarki, Fabien Forest, Francois Casteillo, Sirine Hathroubi, Marios Froudarakis, Michel Peoc'h

J Immunother Cancer. 2020; 8(2): e000597. Published online 2020 Aug 27. doi: 10.1136/jitc-2020-000597

PMCID:: PMC7454240

Abstract Article PDF–2.7M

Select item 739428015.

CD4 and CD8 T Cell Immune Activation during Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7

Marta Catalfamo, Christopher Wilhelm, Lueng Tcheung, Michael Proschan, Travis Friesen, Jung-Hyun Park, Joseph Adelsberger, Michael Baseler, Frank Maldarelli, Richard Davey, Gregg Roby, Catherine Rehm, Clifford Lane

J Immunol. Author manuscript; available in PMC 2020 Jul 31.

Published in final edited form as: J Immunol. 2011 Feb 15; 186(4): 2106–2116. Published online 2011 Jan 21. doi: 10.4049/jimmunol.1002000

PMCID:: PMC7394280

Abstract Article PDF–1.2M

Select item 719487916.

Increased expression of CD8 marker on T-cells in COVID-19 patients

Ali Ganji, Iman Farahani, Behzad Khansarinejad, Ali Ghazavi, Ghasem Mosayebi

Blood Cells Mol Dis. 2020 Jul; 83: 102437. Published online 2020 Apr 13. doi: 10.1016/j.bcmd.2020.102437

PMCID:: PMC7194879

Abstract Article PDF–974K

Select item 715687417.

CD4/CD8 ratio is a prognostic factor in IgG nonresponders among peptide vaccine‐treated ovarian cancer patients

Kayoko Waki, Kouichiro Kawano, Naotake Tsuda, Nobukazu Komatsu, Akira Yamada

Cancer Sci. 2020 Apr; 111(4): 1124–1131. Published online 2020 Mar 6. doi: 10.1111/cas.14349

PMCID:: PMC7156874

Abstract Article PDF–704K

Select item 710540318.

Yonsei Criteria, a Potential Linkage to Intratumoral Foxp3⁺/CD8⁺ Ratio for the Prediction of Oncologic Outcomes in Resected Left-Sided Pancreatic Cancer

Ho Kyoung Hwang, Sung Hwan Lee, Hyoung-Il Kim, Se Hoon Kim, Junjeong Choi, Chang Moo Kang, Woo Jung Lee

Yonsei Med J. 2020 Apr 1; 61(4): 291–300. Published online 2020 Mar 25. doi: 10.3349/ymj.2020.61.4.291

PMCID:: PMC7105403

Abstract Article PDF–1.9M

Select item 649756919.

Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy

Changlong Liu, Carolyn E. Banister, Phillip J. Buckhaults

Cancer Res. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Res. 2019 May 1; 79(9): 2392–2403. Published online 2019 Mar 12. doi: 10.1158/0008-5472.CAN-18-3024

PMCID:: PMC6497569

Abstract Article PDF–2.2M

Select item 620382020.

Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy

Jean-David Fumet, Corentin Richard, Fanny Ledys, Quentin Klopfenstein, Philippe Joubert, Bertrand Routy, Caroline Truntzer, Andréanne Gagné, Marc-André Hamel, Camila Figueiredo Guimaraes, Bruno Coudert, Laurent Arnould, Laure Favier, Aurélie Lagrange, Sylvain Ladoire, Pierre Saintigny, Sandra Ortiz-Cuaran, Maurice Perol, Pascal Foucher, Paul Hofman, Marius Ilie, Sandy Chevrier, Romain Boidot, Valentin Derangere, François Ghiringhelli

Br J Cancer. 2018 Oct 16; 119(8): 950–960. Published online 2018 Oct 15. doi: 10.1038/s41416-018-0220-9

Correction in:: Br J Cancer. 2019 Jul 30; 121(3): 283.

PMCID:: PMC6203820

Abstract Article PDF–1.7M

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