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Items: 1 to 20 of 28

1.
A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis
Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou
Cancer Res Treat. 2022 Apr; 54(2): 525–540. Published online 2021 Jun 29. doi: 10.4143/crt.2021.373
PMCID:
PMC9016320
AbstractArticlePDF–3.0M
2.
Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity
Qiu-Wen Wang, Si-Yao Lu, Yao-Nan Liu, Yun Chen, Hui Wei, Wei Shen, Yan-Fen Chen, Chong-Lei Fu, Ying-Han Wang, Anbang Dai, Xuan Huang, Fred H. Gage, Qi Xu, Jun Yao
Proc Natl Acad Sci U S A. 2020 Dec 8; 117(49): 31438–31447. Published online 2020 Nov 23. doi: 10.1073/pnas.2016416117
Correction in:
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2111933118.
PMCID:
PMC7733786
AbstractArticlePDF–2.5M
3.
Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding
Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari
Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245
PMCID:
PMC7372081
AbstractArticlePDF–2.0M
4.
Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice
Wei Shen, Qiu-Wen Wang, Yao-Nan Liu, Maria C. Marchetto, Sara Linker, Si-Yao Lu, Yun Chen, Chuihong Liu, Chongye Guo, Zhikai Xing, Wei Shi, John R. Kelsoe, Martin Alda, Hongwei Wang, Yi Zhong, Sen-Fang Sui, Mei Zhao, Yiming Yang, Shuangli Mi, Liping Cao, Fred H. Gage, Jun Yao
Proc Natl Acad Sci U S A. 2020 Feb 25; 117(8): 4392–4399. Published online 2020 Feb 10. doi: 10.1073/pnas.1918165117
PMCID:
PMC7049155
AbstractArticlePDF–1.2M
5.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
6.
The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei
Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz
Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2
PMCID:
PMC6746822
AbstractArticlePDF–2.0M
7.
Membrane-Binding Cooperativity and Coinsertion by C2AB Tandem Domains of Synaptotagmins 1 and 7
Hai T. Tran, Lauren H. Anderson, Jefferson D. Knight
Biophys J. 2019 Mar 19; 116(6): 1025–1036. Published online 2019 Feb 5. doi: 10.1016/j.bpj.2019.01.035
PMCID:
PMC6428868
AbstractArticlePDF–1.5M
8.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M
9.
Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells
Zhenhua Fei, Wei Gao, Raoying Xie, Ganzhu Feng, Xiaolin Chen, Yiyan Jiang
Biosci Rep. 2019 Feb 28; 39(2): BSR20181298. Prepublished online 2019 Jan 15. Published online 2019 Feb 8. doi: 10.1042/BSR20181298
PMCID:
PMC6367206
AbstractArticlePDF–1.1M
10.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
11.
Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses
Josef Turecek, Skyler L. Jackman, Wade G. Regehr
Nature. Author manuscript; available in PMC 2018 Apr 30.
Published in final edited form as: Nature. 2017 Nov 23; 551(7681): 503–506. Published online 2017 Oct 30. doi: 10.1038/nature24474
PMCID:
PMC5892411
AbstractArticlePDF–2.8M
12.
Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed at Atomic Detail
Josh V. Vermaas, Emad Tajkhorshid
Biochemistry. Author manuscript; available in PMC 2017 Aug 15.
Published in final edited form as: Biochemistry. 2017 Jan 10; 56(1): 281–293. Published online 2016 Dec 20. doi: 10.1021/acs.biochem.6b00468
PMCID:
PMC5557660
AbstractArticlePDF–3.7M
13.
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn
Cell Syst. Author manuscript; available in PMC 2017 Sep 28.
Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001
PMCID:
PMC5455996
AbstractArticlePDF–3.1M
14.
Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells
Subhankar Dolai, Li Xie, Dan Zhu, Tao Liang, Tairan Qin, Huanli Xie, Youhou Kang, Edwin R. Chapman, Herbert Y. Gaisano
Diabetes. 2016 Jul; 65(7): 1962–1976. Published online 2016 Apr 26. doi: 10.2337/db15-1436
PMCID:
PMC5384637
AbstractArticlePDF–2.5M
15.
Plexin C1 deficiency permits synaptotagmin 7–mediated macrophage migration and enhances mammalian lung fibrosis
Xueyan Peng, Meagan Moore, Aditi Mathur, Yang Zhou, Huanxing Sun, Ye Gan, Jose D. Herazo-Maya, Naftali Kaminski, Xinyuan Hu, Hongyi Pan, Changwan Ryu, Awo Osafo-Addo, Robert J. Homer, Carol Feghali-Bostwick, Wassim H. Fares, Mridu Gulati, Buqu Hu, Chun-Geun Lee, Jack A. Elias, Erica L. Herzog
FASEB J. 2016 Dec; 30(12): 4056–4070. Published online 2016 Sep 8. doi: 10.1096/fj.201600373R
PMCID:
PMC5102121
AbstractArticle
16.
E-cadherin interactome complexity and robustness resolved by quantitative proteomics
Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar
Sci Signal. Author manuscript; available in PMC 2016 Aug 3.
Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473
PMCID:
PMC4972397
AbstractArticlePDF–3.1M
17.
Lateral Diffusion of Proteins on Supported Lipid Bilayers: Additive Friction of Synaptotagmin 7 C2A–C2B Tandem Domains
Joseph K. Vasquez, Kan Chantranuvatana, Daniel T. Giardina, Matthew D. Coffman, Jefferson D. Knight
Biochemistry. 2014 Dec 23; 53(50): 7904–7913. Published online 2014 Dec 1. doi: 10.1021/bi5012223
PMCID:
PMC4278679
AbstractArticlePDF–4.8M
18.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
19.
Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids within the CHARGE Consortium
Weihua Guan, Brian T. Steffen, Rozenn N. Lemaitre, Jason H.Y. Wu, Toshiko Tanaka, Ani Manichaikul, Millennia Foy, Stephen S. Rich, Lu Wang, Jennifer A. Nettleton, Weihong Tang, Xiangjun Gu, Stafania Bandinelli, Irena B. King, Barbara McKnight, Bruce M. Psaty, David Siscovick, Luc Djousse, Yii-Der Ida Chen, Luigi Ferrucci, Myriam Fornage, Dariush Mozafarrian, Michael Y. Tsai, Lyn M. Steffen
Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Jun; 7(3): 321–331. Published online 2014 May 13. doi: 10.1161/CIRCGENETICS.113.000208
PMCID:
PMC4123862
AbstractArticlePDF–430K
20.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
AbstractArticlePDF–630K

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