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Items: 1 to 20 of 123

1.
Targeting Xist with compounds that disrupt RNA structure and X-inactivation
Rodrigo Aguilar, Kerrie B. Spencer, Barry Kesner, Noreen F. Rizvi, Maulik D. Badmalia, Tyler Mrozowich, Jonathan D. Mortison, Carlos Rivera, Graham F. Smith, Julja Burchard, Peter Dandliker, Trushar R. Patel, Elliott B. Nickbarg, Jeannie T. Lee
Nature. Author manuscript; available in PMC 2024 Nov 9.
Published in final edited form as: Nature. 2022 Apr; 604(7904): 160–166. Published online 2022 Mar 30. doi: 10.1038/s41586-022-04537-z
PMCID:
PMC11549687
AbstractArticlePDF–6.4M
2.
Trisomy silencing by XIST: translational prospects and challenges
Khusali Gupta, Jan T. Czerminski, Jeanne B. Lawrence
Hum Genet. 2024; 143(7): 843–855. Published online 2024 Mar 9. doi: 10.1007/s00439-024-02651-8
PMCID:
PMC11294271
AbstractArticlePDF–4.5M
3.
lncRNA XIST Interacts with Regulatory T Cells within the Tumor Microenvironment in Chronic Hepatitis B-Associated Hepatocellular Carcinoma
Burcin Pehlivanoglu, Anil Aysal, Cihan Agalar, Tufan Egeli, Mucahit Ozbilgin, Tarkan Unek, Ilkay Tugba Unek, Ilhan Oztop, Safiye Aktas, Ozgul Sagol
Turk Patoloji Derg. 2024; 40(2): 101–108. Published online 2024 May 18. doi: 10.5146/tjpath.2023.13161
PMCID:
PMC11131571
AbstractArticlePDF–787K
4.
XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression
Keyi Wang, Atrayee Bhattacharya, Naoki Haratake, Tatsuaki Daimon, Ayako Nakashoji, Hiroki Ozawa, Bo Peng, Wei Li, Donald Kufe
Cell Death Dis. 2024 May; 15(5): 330. Published online 2024 May 13. doi: 10.1038/s41419-024-06684-9
PMCID:
PMC11091074
AbstractArticlePDF–4.1M
5.
Long Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box–Binding Homeobox 1 Pathway
Bin Guo, Ming He, Minting Ma, Ziqiang Tian, Jing Jin, Guo Tian
Dig Dis Sci. 2024; 69(4): 1169–1181. Published online 2024 Feb 16. doi: 10.1007/s10620-024-08269-0
PMCID:
PMC11026218
AbstractArticlePDF–1.5M
6.
Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data
Elahe Berenji, Ali Valipour Motlagh, Marziyeh Fathi, Maryam Esmaeili, Tayebeh Izadi, Parsa Rezvanian, Maryam Zanjirband, Zahra Safaeinejad, Mohammad Hossein Nasr-Esfahani
Sci Rep. 2024; 14: 6180. Published online 2024 Mar 14. doi: 10.1038/s41598-024-56524-1
PMCID:
PMC10940664
AbstractArticlePDF–4.8M
7.
Dissection of protein and RNA regions required for SPEN binding to XIST A-repeat RNA
Aileen C. Button, Simone D. Hall, Ethan L. Ashley, Colleen A. McHugh
RNA. 2024 Mar; 30(3): 240–255. doi: 10.1261/rna.079713.123
PMCID:
PMC10870365
AbstractArticlePDF–7.7M
8.
Gender dimorphism in hepatocarcinogenesis—DNA methylation modification regulated X‐chromosome inactivation escape molecule XIST
Zhihui Dai, Sijie Wang, Xinggang Guo, Yuefan Wang, Haozan Yin, Jian Tan, Chenyang Mu, Shu‐Han Sun, Hui Liu, Fu Yang
Clin Transl Med. 2023 Dec; 13(12): e1518. Published online 2023 Dec 26. doi: 10.1002/ctm2.1518
PMCID:
PMC10751514
AbstractArticlePDF–8.8M
9.
Low XIST expression in Sertoli cells of Klinefelter syndrome patients causes high susceptibility of these cells to an extra X chromosome
Liang-Yu Zhao, Peng Li, Chen-Cheng Yao, Ru-Hui Tian, Yu-Xin Tang, Yu-Zhuo Chen, Zhi Zhou, Zheng Li
Asian J Androl. 2023 Nov-Dec; 25(6): 662–673. Published online 2023 May 16. doi: 10.4103/aja202315
PMCID:
PMC10715603
AbstractArticlePDF–12M
10.
The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE
Jonathan D. Crawford, Hong Wang, Daniela Trejo-Zambrano, Raffaello Cimbro, C. Conover Talbot, Jr., Mekha A. Thomas, Ashley M. Curran, Alexander A. Girgis, John T. Schroeder, Andrea Fava, Daniel W. Goldman, Michelle Petri, Antony Rosen, Brendan Antiochos, Erika Darrah
JCI Insight. 2023 Oct 23; 8(20): e169344. Published online 2023 Sep 21. doi: 10.1172/jci.insight.169344
PMCID:
PMC10634230
AbstractArticlePDF–4.7M
11.
Long noncoding RNA X‐inactive specific transcript (lncRNA XIST) inhibits hepatic insulin resistance by competitively binding microRNA‐182‐5p
Guoqing Zhong, Qingping Yang, Yihua Wang, Yuan Liang, Xiaojing Wang, Dongli Zhao
Immun Inflamm Dis. 2023 Nov; 11(11): e969. Published online 2023 Nov 7. doi: 10.1002/iid3.969
PMCID:
PMC10629262
AbstractArticlePDF–1.6M
12.
Association of XIST/miRNA155/Gab2/TAK1 cascade with the pathogenesis of anti-phospholipid syndrome and its effect on cell adhesion molecules and inflammatory mediators
Mai A. Abd-Elmawla, Yumn A. Elsabagh, Nora M. Aborehab
Sci Rep. 2023; 13: 18790. Published online 2023 Nov 1. doi: 10.1038/s41598-023-45214-z
PMCID:
PMC10620142
AbstractArticlePDF–2.2M
13.
Silencing of long noncoding RNA X-inactive specific transcript alleviates Aβ1-42-induced microglia-mediated neurotoxicity by shifting microglial M1/M2 polarization
Kun-Peng Zhao, Xin-Yu Wang, Mei-Qi Shao, Chen-Yang He, Fu-Qiang Yuan
Int J Immunopathol Pharmacol. 2023 Jan-Dec; 37: 03946320231184988. Published online 2023 Jul 3. doi: 10.1177/03946320231184988
PMCID:
PMC10328177
AbstractArticlePDF–2.4M
14.
LncRNA XIST facilitates hypertrophy of ligamentum flavum by activating VEGFA-mediated autophagy through sponging miR-302b-3p
Yanlin Cao, Jianjun Li, Sujun Qiu, Songjia Ni, Yang Duan
Biol Direct. 2023; 18: 25. Published online 2023 May 24. doi: 10.1186/s13062-023-00383-9
PMCID:
PMC10207765
AbstractArticlePDF–5.5M
15.
Knockdown of lncRNA XIST Ameliorates IL-1β-Induced Apoptosis of HUVECs and Change of Tissue Factor Level via miR-103a-3p/HMGB1 Axis in Deep Venous Thrombosis by Regulating the ROS/NF-κB Signaling Pathway
Guangxin Cao, Hua Zhou, Dong Wang, Lei Xu
Cardiovasc Ther. 2022; 2022: 6256384. Published online 2022 Nov 18. doi: 10.1155/2022/6256384
PMCID:
PMC9699739
AbstractArticlePDF–2.4M
16.
miR-150-5p and XIST interaction controls monocyte adherence: Implications for osteoarthritis therapy
Yu-Han Wang, Chun-Hao Tsai, Shan-Chi Liu, Hsien-Te Chen, Jun-Way Chang, Chih-Yuan Ko, Chin-Jung Hsu, Ting-Kuo Chang, Chih-Hsin Tang
Front Immunol. 2022; 13: 1004334. Published online 2022 Sep 20. doi: 10.3389/fimmu.2022.1004334
PMCID:
PMC9530358
AbstractArticlePDF–22M
17.
Extracellular vesicle expansion of PMIS‐miR‐210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism
Steven Eliason, Liu Hong, Yan Sweat, Camille Chalkley, Huojun Cao, Qi Liu, Hank Qi, Hongwei Xu, Fenghuang Zhan, Brad A. Amendt
Clin Transl Med. 2022 Sep; 12(9): e1037. Published online 2022 Sep 18. doi: 10.1002/ctm2.1037
PMCID:
PMC9482803
AbstractArticlePDF–15M
18.
Long non-coding RNA-X-inactive specific transcript inhibits cell viability, and induces apoptosis through the microRNA-30c-5p/Bcl2-like protein 11 signaling axis in human granulosa-like tumor cells
Yichuan Guo, Xueping Peng, Ran Cheng, Hui Chen, Xiaoyan Luo
Bioengineered. 2022; 13(6): 14107–14117. Published online 2022 Jun 22. doi: 10.1080/21655979.2022.2080366
PMCID:
PMC9342309
AbstractArticlePDF–3.5M
19.
B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells
Bingfei Yu, Yanyan Qi, Rui Li, Quanming Shi, Ansuman T. Satpathy, Howard Y. Chang
Cell. Author manuscript; available in PMC 2022 Jun 14.
Published in final edited form as: Cell. 2021 Apr 1; 184(7): 1790–1803.e17. Published online 2021 Mar 17. doi: 10.1016/j.cell.2021.02.015
PMCID:
PMC9196326
AbstractArticlePDF–3.1M
20.
A novel lncRNA-miRNA-mRNA triple network identifies lncRNA XIST as a biomarker for acute myocardial infarction
Peng-Fei Zheng, Lu-Zhu Chen, Peng Liu, Hong-Wei Pan
Aging (Albany NY) 2022 May 15; 14(9): 4085–4106. Published online 2022 May 10. doi: 10.18632/aging.204075
PMCID:
PMC9134965
AbstractArticlePDF–3.1M

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