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Items: 1 to 20 of 33

1.
Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis
Jie Li, Bin Zhang, Zishan Feng, Dandan An, Zhiyuan Zhou, Chao Wan, Yan Hu, Yajie Sun, Yijun Wang, Xixi Liu, Wenwen Wei, Xiao Yang, Jingshu Meng, Mengjie Che, Yuhan Sheng, Bian Wu, Lu Wen, Fang Huang, Yan Li, Kunyu Yang
J Exp Clin Cancer Res. 2024; 43: 28. Published online 2024 Jan 23. doi: 10.1186/s13046-024-02954-8
PMCID:
PMC11040697
AbstractArticlePDF–13M
2.
Neuron-secreted NLGN3 ameliorates ischemic brain injury via activating Gαi1/3-Akt signaling
Zhi-guo Chen, Xin Shi, Xian-xian Zhang, Fang-Fang Yang, Ke-ran Li, Qi Fang, Cong Cao, Xiong-hui Chen, Ya Peng
Cell Death Dis. 2023 Oct; 14(10): 700. Published online 2023 Oct 25. doi: 10.1038/s41419-023-06219-8
PMCID:
PMC10600254
AbstractArticlePDF–5.7M
3.
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism
Le Wang, Vincent R. Mirabella, Rujia Dai, Xiao Su, Ranjie Xu, Azadeh Jadali, Matteo Bernabucci, Ishnoor Singh, Yu Chen, Jianghua Tian, Peng Jiang, Kevin Y. Kwan, ChangHui Pak, Chunyu Liu, Davide Comoletti, Ronald P. Hart, Chao Chen, Thomas C. Südhof, Zhiping P. Pang
Mol Psychiatry. Author manuscript; available in PMC 2024 Apr 24.
Published in final edited form as: Mol Psychiatry. 2024 Jun; 29(6): 1620–1635. Published online 2022 Oct 24. doi: 10.1038/s41380-022-01834-x
PMCID:
PMC10123180
AbstractArticlePDF–2.8M
4.
Autism-linked NLGN3 is a key regulator of gonadotropin-releasing hormone deficiency
Roberto Oleari, Antonella Lettieri, Stefano Manzini, Alyssa Paganoni, Valentina André, Paolo Grazioli, Marco Busnelli, Paolo Duminuco, Antonio Vitobello, Christophe Philippe, Varoona Bizaoui, Helen L. Storr, Federica Amoruso, Fani Memi, Valeria Vezzoli, Valentina Massa, Peter Scheiffele, Sasha R. Howard, Anna Cariboni
Dis Model Mech. 2023 Mar 1; 16(3): dmm049996. Published online 2023 Mar 28. doi: 10.1242/dmm.049996
PMCID:
PMC10110398
AbstractArticle
5.
Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders
Zhenzhen Zhang, Mengzhuo Hou, Huaxing Ou, Daping Wang, Zhifang Li, Huawei Zhang, Jianping Lu
Front Endocrinol (Lausanne) 2022; 13: 1067529. Published online 2022 Nov 21. doi: 10.3389/fendo.2022.1067529
PMCID:
PMC9719943
AbstractArticlePDF–6.8M
6.
Neuronal-driven glioma growth requires Gαi1 and Gαi3
Yin Wang, Yuan-yuan Liu, Min-bin Chen, Kai-Wen Cheng, Li-na Qi, Zhi-qing Zhang, Ya Peng, Ke-ran Li, Fang Liu, Gang Chen, Cong Cao
Theranostics. 2021; 11(17): 8535–8549. Published online 2021 Jul 25. doi: 10.7150/thno.61452
PMCID:
PMC8343996
AbstractArticlePDF–4.3M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
The Arg451Cys-Neuroligin-3 Mutation Associated with Autism Reveals a Defect in Protein Processing
Davide Comoletti, Antonella De Jaco, Lori L. Jennings, Robyn E. Flynn, Guido Gaietta, Igor Tsigelny, Mark H. Ellisman, Palmer Taylor
J Neurosci. 2004 May 19; 24(20): 4889–4893. doi: 10.1523/JNEUROSCI.0468-04.2004
PMCID:
PMC6729460
AbstractArticlePDF–244K
9.
Gastrointestinal dysfunction in patients and mice expressing the autism‐associated R451C mutation in neuroligin‐3
Suzanne Hosie, Melina Ellis, Mathusi Swaminathan, Fatima Ramalhosa, Gracia O. Seger, Gayathri K. Balasuriya, Christopher Gillberg, Maria Råstam, Leonid Churilov, Sonja J. McKeown, Nalzi Yalcinkaya, Petri Urvil, Tor Savidge, Carolyn A. Bell, Oonagh Bodin, Jen Wood, Ashley E. Franks, Joel C. Bornstein, Elisa L. Hill‐Yardin
Autism Res. 2019 Jul; 12(7): 1043–1056. Published online 2019 May 22. doi: 10.1002/aur.2127
PMCID:
PMC6606367
AbstractArticlePDF–1.7M
10.
Significance of neurexin and neuroligin polymorphisms in regulating risk of Hirschsprung’s disease
Yanhong Li, Hui Liu, Yubin Dong
J Investig Med. 2018 Jun; 66(5): 1–8. Published online 2018 Apr 4. doi: 10.1136/jim-2017-000623
PMCID:
PMC5992363
AbstractArticlePDF–487K
11.
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma
Humsa S. Venkatesh, Lydia T. Tam, Pamelyn J. Woo, James Lennon, Surya Nagaraja, Shawn M. Gillespie, Jing Ni, Damien Y. Duveau, Patrick J. Morris, Jean J. Zhao, Craig J. Thomas, Michelle Monje
Nature. Author manuscript; available in PMC 2018 Apr 10.
Published in final edited form as: Nature. 2017 Sep 28; 549(7673): 533–537. Published online 2017 Sep 20. doi: 10.1038/nature24014
PMCID:
PMC5891832
AbstractArticlePDF–1.4M
12.
Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene
Matías A. Medina, Víctor M. Andrade, Mario O. Caracci, Miguel E. Avila, Daniela A. Verdugo, Macarena F. Vargas, Giorgia D. Ugarte, Ariel E. Reyes, Carlos Opazo, Giancarlo V. De Ferrari
Transl Psychiatry. 2018; 8: 45. Published online 2018 Mar 5. doi: 10.1038/s41398-018-0093-y
PMCID:
PMC5835496
AbstractArticlePDF–1.3M
13.
Not all neuroligin 3 and 4X missense variants lead to significant functional inactivation
Xiaojuan Xu, Zhengmao Hu, Lusi Zhang, Hongfang Liu, Yuemei Cheng, Kun Xia, Xuehong Zhang
Brain Behav. 2017 Sep; 7(9): e00793. Published online 2017 Aug 14. doi: 10.1002/brb3.793
PMCID:
PMC5607556
AbstractArticlePDF–997K
14.
FOLDING ANOMALIES OF NEUROLIGIN3 CAUSED BY A MUTATION IN THE α/β-HYDROLASE FOLD DOMAIN
Antonella De Jaco, Noga Dubi, Davide Comoletti, Palmer Taylor
Chem Biol Interact. Author manuscript; available in PMC 2017 Sep 4.
Published in final edited form as: Chem Biol Interact. 2010 Sep 6; 187(1-3): 56–58. Published online 2010 Mar 12. doi: 10.1016/j.cbi.2010.03.012
PMCID:
PMC5582339
AbstractArticlePDF–882K
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
17.
Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses
Quynh-Anh Nguyen, Meryl E Horn, Roger A Nicoll
eLife. 2016; 5: e19236. Published online 2016 Nov 2. doi: 10.7554/eLife.19236
PMCID:
PMC5098909
AbstractArticlePDF–4.5M
18.
Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort
Martina Landini, Ivan Merelli, M. Elisabetta Raggi, Nadia Galluccio, Francesca Ciceri, Arianna Bonfanti, Serena Camposeo, Angelo Massagli, Laura Villa, Erika Salvi, Daniele Cusi, Massimo Molteni, Luciano Milanesi, Anna Marabotti, Alessandra Mezzelani
Int J Mol Sci. 2016 Oct; 17(10): 1765. Published online 2016 Oct 22. doi: 10.3390/ijms17101765
PMCID:
PMC5085789
AbstractArticlePDF–513K
19.
Widespread expansion of protein interaction capabilities by alternative splicing
Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal
Cell. Author manuscript; available in PMC 2017 Feb 11.
Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029
PMCID:
PMC4882190
AbstractArticlePDF–1.9M
20.
Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion
Humsa S. Venkatesh, Tessa B. Johung, Viola Caretti, Alyssa Noll, Yujie Tang, Surya Nagaraja, Erin M. Gibson, Christopher W. Mount, Jai Polepalli, Siddhartha S. Mitra, Pamelyn J. Woo, Robert C. Malenka, Hannes Vogel, Markus Bredel, Parag Mallick, Michelle Monje
Cell. Author manuscript; available in PMC 2016 May 7.
Published in final edited form as: Cell. 2015 May 7; 161(4): 803–816. Published online 2015 Apr 23. doi: 10.1016/j.cell.2015.04.012
PMCID:
PMC4447122
AbstractArticlePDF–1.9M

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